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Bupe Euphoric or Not?

Bupe33309 said:
same here. this is my second go around been on since dec 2009 and first time was in 2001. I feel no pain relief, euphoria, nothing!! even with 4 valiums on top of it. Now if i take a few somas with them i get kegless. but sometimes i like adderall better which i get also cause subutex is just keeping me normal. beats chasing the dope man and running out every month though.
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It's because methadone is pretty much the rich mans heroin, it's just like switching from OXY to Heroin... You're addiction is more focused on the euphoria and the rush. Suboxone is designed to just stop your receptors from bitching, it fills them so they don't want more, It's not designed for the euphoria and analgesia.
 
Captain.Heroin said:
I disagree; I have tried subutex and Suboxone (film and tablets) at similar dosages for all three, and all produce identical effects for myself.
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Not so for me though.

A subjective experience of chemical combos and variant body reactants, means experienced will vary.
 
I really wouldn't consider Sub's to be a combo.


The Naloxone isn't an active drug, only there to scare people from abusing them, which doesn't work haha.
 
ok now I know you can shoot subs from doing it myself a lot in the past, but for all those who have shot high doses of tex AND suboxone, was there a difference? what I noticed with suboxone was that a dose over 1 mg I.V, just doesn't hit the same way that one mg or under does. for instance if you shoot .5 mg of suboxone, you'll start to feel it immediately, granted full effects take about 10 minutes or so. but if I shoot 2 mg, I will feel it, but it seems to take about half an hour or longer, as if I had taken it sublingually. This experience leads me to wonder if that's just the general way I.V bupe works, or if at this point the .5 mg of naloxone does briefly combat the buprenorphine for a little while, before losing.
 
Jordie said:
It's because methadone is pretty much the rich mans heroin, it's just like switching from OXY to Heroin... You're addiction is more focused on the euphoria and the rush. Suboxone is designed to just stop your receptors from bitching, it fills them so they don't want more, It's not designed for the euphoria and analgesia.
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"methadone is pretty much the rich mans heroin' What Th ?
it's just like switctching from OXY to heroin" WHAT THE ???
 
I'm not comparing prices, I'm comparing the use. If you go from Oxy to Heroin and Heroin to Methadone, its basically the same as going from Heroin to Oxy. You are just switching drug names, they all effect your receptors the same way. With Suboxone it isn't designed to be like other opiates, it's only designed to fill the receptors so they stop bitching for more opiates.
 
Nope. Not for me after the first three doses.

First dose is always the strongest. Rule of thumb for pharmacology for most drugs, anyways.
 
Jordie said:
It's because methadone is pretty much the rich mans heroin, it's just like switching from OXY to Heroin... You're addiction is more focused on the euphoria and the rush. Suboxone is designed to just stop your receptors from bitching, it fills them so they don't want more, It's not designed for the euphoria and analgesia.
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Uh, no.

You are thinking of Oxymorphone.

How do you even get methadone as being the rich man's heroin? It costs $80 to be maintained on methadone a week at a methadone maintenance clinic, and produces very little euphoria while screwing up the body.

I am doubting you know anything about opiates right now, sir.
 
I used to have an euphoric feeling first times I shoot it iv. But now even 4-8mg iv. doesn´t make any feeling at all so it get´s you a tolerance quite fast. The high and euphoria from bube is nothing compared to Morphin or Oxycodone but the great feeling from it last´s like for ever... ;) Fentanyl is the last substance I´ve been getting out of patches to inject and it gets you high for a short while and then it goes down instantly. Then you should shoot another load in a small while, expensive and tough for veins.

-Hooddood78
 
Znegative said:
ok now I know you can shoot subs from doing it myself a lot in the past, but for all those who have shot high doses of tex AND suboxone, was there a difference? what I noticed with suboxone was that a dose over 1 mg I.V, just doesn't hit the same way that one mg or under does. for instance if you shoot .5 mg of suboxone, you'll start to feel it immediately, granted full effects take about 10 minutes or so. but if I shoot 2 mg, I will feel it, but it seems to take about half an hour or longer, as if I had taken it sublingually. This experience leads me to wonder if that's just the general way I.V bupe works, or if at this point the .5 mg of naloxone does briefly combat the buprenorphine for a little while, before losing.
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For myself I consider 0.2mg IV/IM a large dosage, as I've currently tapered to roughly 1/3rd of that, or lower. :) I had to restart my tapering plans starting the beginning of this year.

Anything above 0.2mg, IMO, for someone with my sensitivity/tolerance, is a total waste. I would only ever use a whole 0.2mg shot again in case I was in severe pain. Trust me, you don't want to ruin your tolerance to bupe and then be in severe pain. Trust the Captain on this one ;) when I broke both bones in my arm, I had already tapered down to 0.026mg per shot, and had plans for tapering further from there as well. So when I went all the way back up to 0.2mg, it actually did work kind of well compared to whatever they would have given me at the ER (hydrocodone/APAP, or weaker).

Personally if you're noticing differenes between dosages over 0.2mg, it's because you're doing too much in a single shot.
 
jesus CH .026mg?? haha thats fucking awesome that you got that low. Was there any point where you actually felt that you started feeling the buprenorphine even after you stabilized on a dosage? I ask because I know i felt more sedation and stuff on two mg/day but at one mg (the dose I've been on for about three weeks) feels more energizing, though It's starting to have the same side effects when it wears off that I hate about higher dosages of suboxone, apathy, lethargy etc.. so I figure I'm going to taper down to .5 mg once I get my next prescription. I'm going to get the 2 mg strips now (I got on medicaid, take that R&B!) which I figure will make tapering a bit easier through the SL ROA as I'm getting sick of cutting the 8 mg films into 16 different tiny pieces. (not to mention they're cracked to shit) But I guess what I want to know, is what the lowest dosage buprenorphine could be active at?
 
Znegative said:
ok now I know you can shoot subs from doing it myself a lot in the past, but for all those who have shot high doses of tex AND suboxone, was there a difference? what I noticed with suboxone was that a dose over 1 mg I.V, just doesn't hit the same way that one mg or under does. for instance if you shoot .5 mg of suboxone, you'll start to feel it immediately, granted full effects take about 10 minutes or so. but if I shoot 2 mg, I will feel it, but it seems to take about half an hour or longer, as if I had taken it sublingually. This experience leads me to wonder if that's just the general way I.V bupe works, or if at this point the .5 mg of naloxone does briefly combat the buprenorphine for a little while, before losing.
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I don't know if that is possible, I guess it could be but from what I understand the Naloxone under the tongue or IV'ed is not water soluble so it won't get into your blood stream unless maybe you eat it. But if it does work the way you are proposing, it would definitely do exactly what you are saying by combating it and then finally losing.
 
I don't think Naloxone has a higher affinity at the mu receptor sites than Bupe.

Although if you are using a smaller amount of the drug it's possible the naloxone binds FIRST just by luck, before the sub kicks it off. That brief second of being stimulated by an antagonist might make the agonist effects of the bupe so much better? Like it puts you into withdrawals (at least your brain thinks it) so it's more of a relief gap between that and where the bupe brings you, compared to say normal and the sub?

brief naloxone withdrawal -> bupe high +10
feeling normal -> bupe high +5
 
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