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Ether Addiction?

Ether.

It's fucking great.
It eats your brain if you over do it.
If you do over do it, you will know about it! Worst bloody 'hangover' of my life.
Interesting time stopping/travel 'experiences'.
Exceedingly addictive in the short term, up there with crack.
Your breath will smell for up to 4 days afterwards, I don't think it's metabolised and just diffuses from your system. The fatter you are the longer it lasts.
It's fun to give people for some reason.
 
Many anesthetics are addictive. Ketamine is mildly addictive. Fentanyl is habit forming. Demerol is addictive. Benzodiazepines are mildly addictive. Morphine is addictive. But ether (and the halothanes) are right up there with over the counter Duster (aerosol computer keyboard cleaner) or Freon (air conditioner fluid) in my opinion.

Sorry, but you'd have to be pretty hard up to get hooked on that shit. Then again, I know someone who went on a recent drinking binge and ended up hitting the isopropyl alcohol and acetone before it was over--he landed in the hospital for 3 days, by the way--so I guess one should never say it won't happen to them when it comes to addiction which is, to use Alcoholic Anonymous's phrase, no doubt, "cunning, baffling, and powerful."

Propofol (2,6-diisopropylphenol), on the other hand, is one anesthetically employed drug which I could easily get addicted to in a heartbeat. I've only done it IV--total blissful, euphoric relaxation--but I bet it's just as good by mouth (just a hunch). Achtung!: My Physicians' Desk Reference claims many a anesthesiologist has died from propofol overdose, so be careful if you go that route.

Ether is best used on crystallizations.
 
<pyridinyl_30> said:
Propofol (2,6-diisopropylphenol), on the other hand, is one anesthetically employed drug which I could easily get addicted to in a heartbeat. I've only done it IV--total blissful, euphoric relaxation
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Dosages?
 
drinking IPA and tone? sheesh bugger me upside down if that doesn't reek of desperation (and nail varnish remover:P)

I recall reading someone state that propofol must be injected, and isn't active orally, not that I wouldn't give it a go or three.

Compared to drinking ethanol, I don't see why ether should be particularly worse, taken orally at any rate, which is my preferred ROA, AFAIK it doesn't have the hepatotoxicity of ethanol (anyoke know how its metabolised/more on its pharmacology in vivo?)

Not something I would want to do too often, but I used to do it sometimes, I didn't find it a particularly social drug, but then again I am autistic, so I don't really get much out of 'doing social' in the first place, it used to go down a bomb though when I brought it to outdoor parties, people loved the stuff.
 
I was legitimately addicted to huffing ether for the span of about 6 months. I repeatedly broke into my school's chemistry lab to steal 1-L bottles of 99.9% diethyl ether. A liter of ether would last me about a month if I didn't binge too hard. Total I consumed maybe around 6-7 L all to myself.

I think the key to discovering ether's power is administering it CORRECTLY. Most people probably just douse a rag and put it on their face, which will put you on the fast track to vomit-land. What I did was punch a tiny hole in the cap of my ether bottle. I would tip it over and let about a dozen drops form a small wet spot. This would give me about 3-4 metered huffs before it evaporated. Then repeat as needed. This will gradually increase the amount of ether in your system so you don't get overwhelmed, and you can feel what's happening at every stage of the high. Interestingly, ether kind of smells like peppermint or camphor at high concentrations.

Inhaling ether was EXTREMELY addictive! Like one poster said, up there with crack. I would sit on my porch for upwards of 6 hours continually pouring ether on a shirt and huffing it. Pharmacologically it feels very similar to a combination of nitrous and booze, but the rapid onset of action is what makes it addictive. In about 60 seconds I would go from sober to 12-pack hammered. The background noise of trees rustling and cars passing by would amplify until it sounded like a rushing waterfall. My air conditioner's hum would fragment into a choppy sound. Colors became intensely bright and music sounded completely alien. And there was INTENSE euphoria, all I could do was tip the ether jug, soak the rag a little bit more, and keep it going...

Use with caution!!!
 
Have you noticed any long term consequences of your binging?

It's often said that inhalant use is equally bad for you, bar nitrous, but this was used for so long, and I see fairly little information about toxicity. Sure there is some, but specifically what?
 
I did abuse it horrendously at one point, for quite some time, and I haven't noticed any long term sequelae.
 
Ham-milton said:
It's often said that inhalant use is equally bad for you, bar nitrous, but this was used for so long, and I see fairly little information about toxicity. Sure there is some, but specifically what?
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i've heard that inhalant use pretty much fucks you up except ether and nitrous, with the former being irritant to your airways and the latter depleting your cobalamine. of course i'm not sure on that and i don't have anything to back that up but i would love to see some data on how harmful these 'safe'(?) inhalants really are.
 
^
I dont think its by far as unhealthy as duster and that kind of stuff

doesnt cause those bad headaches either more like a hangover

I do think its worse than alcohol

also i suspect the withdrawals to be hell and even dangerous (seizure risk)
 
Anyone know what diethyl ether is metabolized to (if anything)?
 
tobala said:
Anyone know what diethyl ether is metabolized to (if anything)?
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not in significant quantities as far as i know. it is simply exhaled instead.
 
Ether is not in any meanings as bad for you're brains as gasoline or glue. Ether is one of the most safest anesthetic for the brains that have ever been used. The reason why it isn't used as anesthetic anymore (in america & europe) is that its highly dangerous, by having really low flame-point. The real bad sides of ether are because ether will transform to ethyl acohol if you drink it.

Ether is like poppers and N2O, its an safe "inhalant". Only some an ignorant fool would think that ether is like huffing glue or gasoline.

So please people, do not talk about something that you dont know (I mean those who think that ether make you retard like glue huffer)...

As for Ether Addiction, I have heard that it can cause something like delirium tremens from really long use.

I know that ether can be pretty addictive, when you start to take it you cant stop til the ether has finished. Pretty much same as with N2O. Ether is dissociative drug, it gives with high amounts pretty much same effects as with DXM 3. plateau.
 
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All so scientific...

I'd like to see some evidence for what you're saying.

Poppers are NOT a safe inhalant at all, either.
 
I don't think ether should be characterized as "safe". Like I had mentioned before, there are probably some hepatotoxicity issues with issues.

Acetaminophen (Tylenol) is a widely used analgesic/antipyretic drug which is enzymatically bioactivated, or toxified, by the cytochromes P-450 to a hepatotoxic reactive intermediary metabolite. Brief general anesthesia with diethyl ether has been shown to inhibit both the toxifying cytochromes P-450 and enzymatic glucuronidation, the latter constituting up to 60% of acetaminophen elimination via a nontoxifying pathway. Thus ether potentially could produce a temporally differentiated inhibition of bioactivating and "detoxifying" pathways, resulting in an enhancement of acetaminophen hepatotoxicity if the balance favored bioactivation. To evaluate this possibility, separate groups of male NIH strain mice were treated with acetaminophen at different times after 5 min of anesthesia with ether. Ether produced a 40-fold enhancement in acetaminophen hepatotoxicity as determined by plasma glutamic-pyruvic transaminase (GPT) concentrations. This toxicologic enhancement was observed only if acetaminophen administration was delayed, with a maximal enhancement when acetaminophen was given 6 hr after ether, and no effect with a delay of 16 hr. Similar studies in male CD-1 mice were carried out using halothane (Fluothane) as the general anesthetic given either over 5 min or over 1 hr. While halothane given over 5 min had no effect, a 1 hr anesthetic duration produced a 10-fold increase in acetaminophen hepatotoxicity as determined by peak GPT concentration, with no observed hepatotoxicity in the halothane controls. Toxicologic enhancement occurred only with delayed administration of acetaminophen; however, the maximal enhancement observed with a 6-hr delay was still evident with a 12-hr delay. Conversely, inhibition of acetaminophen hepatotoxicity was observed if acetaminophen was given either 2 hr or 18 hr after halothane.(ABSTRACT TRUNCATED AT 250 WORDS) http://www.ncbi.nlm.nih.gov/pubmed/3699320?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=4&log$=relatedarticles&logdbfrom=pubmed
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In a number of things i've read, halothane is somewhat more toxic when compared to diethyl ether (halothane is not as commonly used as it once was), but both can cause liver damage...
 
They stil use diethy ether as a emergency anaesthetic in Australia, ambo's generally have it on hand.... It made me vomit my face off.
 
negrogesic said:
I don't think ether should be characterized as "safe". Like I had mentioned before, there are probably some hepatotoxicity issues with issues.



In a number of things i've read, halothane is somewhat more toxic when compared to diethyl ether (halothane is not as commonly used as it once was), but both can cause liver damage...
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Yes, it can be hepatotoxic (by drinking or inhaling?), but I was speaking about neurotoxicity. Some stupid people think that ether kills your brain cells and make you retard like huffing gasoline or glue, maybe they themselfs have huffed too much jenkem or something...

Maybe ether is hepatotoxicy because it turns to ethanol when you drink it?

And when I used word "safe" with ether, poppers and N2O, I meant that they aren't neurotoxins so they do not cause any sort of brain cell losses or make you retard.
 
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