Hi i suffer from chronic depression since the age of 12 . I have used alot of antidepressants without any beneficial effects and it even harmed me significantly (paxil) i am interested in the use of other meds for depression . I have used ghb for depression (not advisable addiction) kratom and suboxone . Opioide based medication/drugs seems to rlly help . But i know this is very well known and isn't most of the times an option to treat depression in the long run because of addiction . Now i am interested in esketamine , it seems a nasal spray is fda approved . The only thing what bugs me is that it has strictly to be used in a "medical setting" while they regulate blood pressure . I rlly don't understand why this is so strictly regulated ? I mean i can get stimulants prescribed with ease . Also why can strong opiode based medication like oxy be used at home while esketamine in nasal spray not ? What is the purpose of this ? Is it because its a dissociative? I know ketamine is extremely safe even in overdosis (you can't die from od) so why can this only be used in medical setting? . Also the bp increase seems very minimal compared to stimulants. Any people here used ketamine for depression with succes ? Anhedonia is my worst symptom which ssri's only worsen . Any advice is appreciated . Also i would like to say i have done ketamine recreational and i rlly don't see myself ever getting addicted to that . Ketamine high feels weird and cold and there is zero Euphoria or good feelings associated .
Thanks for reading and Greetings !
Thanks for reading and Greetings !