Ecstasy, effexor, concerta, alcohol, weed

[glowglow]

If I take concerta and effexor in the morning and then before a concert a night, take an xtc pill and drink and smoke a little, would it enhance the effects of the xtc?

 

[Darksidesam]

Effexor and mdma (ecstasy) , combined, there is a risk of Serotonin syndrome (which is potentially a fatal reaction, at the least a very unpleasant and nasty one)
http://en.wikipedia.org/wiki/Serotonin_syndrome

 

[somedud]

Effexor will block the effects of MDMA almost completely, even if youve been on it for a while.

 

[ChronicHD]

Depends on how much Effexor you are prescribed (dose), and the half-life. If you take an SSRI, you need to stop taking it for at least a few days before the roll in order to feel the full effects.

Effexor is not an SSRI, because by definition SSRIS (selective serotonin reuptake inhibitors) ONLY inhibit the reuptake of serotonin. Effexor also inhibits the reuptake of norepinephrine, which SSRIs do not significantly do. Thus, Effexor is an SNRI (serotonin norepinephrine reuptake inhibitor) and has properties of SSRIs as well as its own norepinephrine properties.
Because Effexor strongly inhibits the reuptake of serotonin, just like SSRIs do, it is not possible to roll on Effexor.

However, some people find that the withdrawal effects from SSRI's are too horrible and not worth abstaining from just for a roll. Some people can get away with it, but others become very anxious, panicked, dizzy, light-headed, etc, from SSRI withdrawal.

 

[Folley]

^ MDMA works on norepinephrine too, so if its blocking sert and norp that your probably not going to notice anything from the MDMA

Weed is ok to use with any drug, ever. Alcohol is safe with most, just be careful when mixing with downers and dont drink stupidly. Concerta is like speed, so your going to have a lot of added neurotoxicity if you use that withing the days leading up too and after your roll.


I would say dont even bother with the E...

 

[severely etarded]

stop doing drugs

 

[gooballs]

This sounds like a great way to get serotonin syndrome.. take it from me because i got it myself mixing drugs similar to effexor with MDMA stop taking all that other shit if you want to roll.. I honestly would advice you not to roll for a couple weeks after stopping the other medications, but thats because I've recently experienced SS first hand and it currently remains to be the worst period of my life. Don't roll on that shit man, you probably shouldn't roll at all for the time being. Not only will you have to do what someone abose me said to roll, which is stop taking any anti-depressants for a period of time before your roll, but you also should not take any SSRI's or SNRI's for several days after you roll.

 

[MikeRWK]

Effexor is only an SNRI at doses >150mg. It will kill your roll anyways, unless you take alot of pills then you'll get a short lasting speedy high that i compare to coke.When i was on paxil i took 4 beans at once, was fucking HIGH for 2 hours, then went to sleep.I also drank about 18 beer that night, but ive always drank a ton of beer then popped e to bring me out of it. Looking back on it now it was beyond stupid.