fastandbulbous
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EADD Benzo Discussion V. Waking up in a Wakefield skip
- Thread starter ordinary mind
- Start date
matt<3ketamine
Bluelighter
Have you tried Nitraz? it absolutely wrecks ya, it was my fave to get a nod really going but incredibly dodgy if mixed with opi's
axe battler
Bluelight Crew
Yeah, used to love nitrazepam but yeah mixed with opiates it would fuck me up.
peace seeker 76
Bluelighter
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- Nov 9, 2022
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I had to quit my shitty job do get off benzos. easy said then done
Fertile
Bluelighter
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Yes - the Dutch study showed an over-representation of deaths due to mixing nitrobenzodiazepines and opiates. Mixing ANY CNS depressants is bad and yes, lots of deaths involved opiates and diazepam, alprazolam and oxazepam as well. (prescribed in The Netherlands) Also Z-drugs are over-represented. I suspect that it's because both the Z-drugs and the nitrobenzodiazepines have a high a1 affinity - the one that makes you sleep/nod or if you remain awake, it's the one that causes loss of executive function so loss of judgment and mood lability are common. So people do daft things.
Just yesterday my friend realized that the Z-drugs are the closest thing we have to a 'truth serum' because someone who has a1 PAM and is kept away will have no ability to control themselves.
Look at the cases of 'air rage' and even 'post rage'. People do not make good decisions if you PAM their a1 receptors. I don't know id the Z-drugs are less selective and can bind to all a1 receptors (their are 4 important ones) but their are many variations in the GABA receptor.
Social Psychiatry vol. 47 iss. 2
Ten-year trends in benzodiazepine use in the Dutch population
2011 January 23
Pages: 293--301
This is an excellent study. If anyone want's the .PDF then just ask. I'm not a sociologist so it's not my field. Someone with the appropriate education might find it of more value than it was to me (and I still find the trend a bit worrying).
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Forever Changes
Bluelighter
yeah I've done some daft/crazy things after having taken too many benzos, irrational things that I have no memory of the next day. I'm just fortunate I never did anything really dangerous and I'm more careful now. It really is like your body is capable of doing things but your mind is still in a dream-state so you're not at all acting in a rational way. It's one of the reasons I never wanted to use Zolpidem as that's notorious for that kind of thing too. I use Zopiclone sometimes, but not in mega-doses
Strange thing is, I've sometimes had the same experience with Tapentadol - waking up to find I've done irrational things I have no memory of - but that's not even a Benzo, it's an opioid!
Fertile
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Tapentadol? It's an odd drug and so close to being a potentially good one. If you put a methyl side-chain on the benzylic carbon of a phenolic benzene ring, it's antagonist. If you place an ethyl chain it's a mixed agonist/antagonist and if you place an N-propyl... it's a full agonist. Look at Picenadol. It overlays
But surprised to learn it has such effects because have NET & SERT transporters. So I had assumed it would wake people up.
Useful information - maybe it has affinity at other sites? I will hit the papers and let you know!
BTW obviously tapentadol has a (chiral) ethyl moiety.
IF people liked tapentadol, 'tahexadol' (see my claver naming) SHOULD be a lot better. As I say, picenadol is the closest and it has an n-propyl BUT it isn't enantiomer pure. So one trans isomer is an agonist, the other is an antagonist.
But surprised to learn it has such effects because have NET & SERT transporters. So I had assumed it would wake people up.
Useful information - maybe it has affinity at other sites? I will hit the papers and let you know!
BTW obviously tapentadol has a (chiral) ethyl moiety.
IF people liked tapentadol, 'tahexadol' (see my claver naming) SHOULD be a lot better. As I say, picenadol is the closest and it has an n-propyl BUT it isn't enantiomer pure. So one trans isomer is an agonist, the other is an antagonist.
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fastandbulbous
Bluelight Crew
If it has serious kappa opiate agonist activity, my experiences with pentazocine, many moons ago, is a solid no to ingestion by any route...
Smuck_Hey_Dee_Hewitt
Bluelighter
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- 80
Do not take this personally but that is all a bunch of speculative nonsense. ( Huge hypocrisy regarding this theme. ) Benzos and Opiates are 100% safe. (Here we go again ... ) if you drink a pint of lager you might feel somewhat goofier, right ? If you do drink your body weight in lager you might just die. Yeah ?
I´ve always used , at times abused, benzos and (both ) opiates/oids simultaneously with no negative side effects at all (well ,besides ruining my personal life and making others around me miserable, subsequently absent as a consequence ) .
You might see me as the "The exception " ,happens I am "The norm " (NA/AA centers are there to prove it -majority of people in there ,are there for polydrug (ab)use issues ).
Not discrediting that study 100% for obvious reasons ,but the Big majority of people in here know perfectly well that , therapeutic doses ,it is perfectly safe to combine Opiates/oids + benzos ... a lot would even use 1st generation anti histamines and others ( again ,moderation and common sense ) to add to
the sedation/oblivion .
You just have to do your research and use common sense ( as much as possible that is. ). Plus, chances are your Psychiatrist ( or whoever writes your prescriptions ) will back you up on this. Mine certainly did when I appeared with "Sleeplessness " as a side effect to Buprenorphine. Wrote me a script for Oxazepam right on spot and told me when and how to take it - that is part of his job description if I´m not mistaken.
As for the Psychosocial aspects of it ... " Cases of air rage " and all that ... . Neither benzos nor Z drugs cure "bad manners " and other pre existing personality traits .
I apologize if that sounded personal since I´m hardly "shooting the messenger " in here . It´s just far too many years of , on and off, addiction ,and to such combos in particular ,to let that one slide ... ( that and endless hours ,flying from here to there , under the influence, witnessing "normal people " unable to control their alcohol, thus abusing others as the consequence , all this whilst I nodded away peacefully, oblivious to their antics
) .Take care .
Fertile
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Why did people mix it with tripelennamine? I'm guessing someone was once prescribed the two and noted the 'euphoria'. The JAMA notes 'long abused in the medical community, it has become popular among street addicts. So one HOPES the medical profession infers people have some understanding of the interaction... but maybe not. Propofol is the new toy that anesthetists abuse. Doesn't SOUND 'euphoric' to me.
matt<3ketamine
Bluelighter
"benzos and opiates are 100% safe" would mean there has never been a death from them and legal.Do not take this personally but that is all a bunch of speculative nonsense. ( Huge hypocrisy regarding this theme. ) Benzos and Opiates are 100% safe. (Here we go again ... ) if you drink a pint of lager you might feel somewhat goofier, right ? If you do drink your body weight in lager you might just die. Yeah ?
I´ve always used , at times abused, benzos and (both ) opiates/oids simultaneously with no negative side effects at all (well ,besides ruining my personal life and making others around me miserable, subsequently absent as a consequence ) .
You might see me as the "The exception " ,happens I am "The norm " (NA/AA centers are there to prove it -majority of people in there ,are there for polydrug (ab)use issues ).
Not discrediting that study 100% for obvious reasons ,but the Big majority of people in here know perfectly well that , therapeutic doses ,it is perfectly safe to combine Opiates/oids + benzos ... a lot would even use 1st generation anti histamines and others ( again ,moderation and common sense ) to add to
the sedation/oblivion .
You just have to do your research and use common sense ( as much as possible that is. ). Plus, chances are your Psychiatrist ( or whoever writes your prescriptions ) will back you up on this. Mine certainly did when I appeared with "Sleeplessness " as a side effect to Buprenorphine. Wrote me a script for Oxazepam right on spot and told me when and how to take it - that is part of his job description if I´m not mistaken.
As for the Psychosocial aspects of it ... " Cases of air rage " and all that ... . Neither benzos nor Z drugs cure "bad manners " and other pre existing personality traits .
I apologize if that sounded personal since I´m hardly "shooting the messenger " in here . It´s just far too many years of , on and off, addiction ,and to such combos in particular ,to let that one slide ... ( that and endless hours ,flying from here to there , under the influence, witnessing "normal people " unable to control their alcohol, thus abusing others as the consequence , all this whilst I nodded away peacefully, oblivious to their antics
Take care .
tell that to any of the friends who had to keep me alive with CPR whilst an ambulance arrived, especially the one who did it for ages after a full barrel of naloxone, after just a bag of brown and a 2mg xanax bar (not tons and tons).
I've also never stole a thing in my life, so i don't have that 'bad manners' or pre-existing personality trait for pinching stuff, yet only time ive 'shoplifted' i took a drink from a can of red bull on the shelf and put it back and walked out of the shop only whilst basically out of it on alprazolam/xanax, and came to with a £80 police fine in my pocket, really confused and had to get filled in by my mates on what happened, even they didn't know why i did that (so deffo not my type of pre-existing personality). Yet i take xanax now and i don't steal or do stupid shit.
matt<3ketamine
Bluelighter
urgh propofol, lava in the veins from the milk of amnesia
Fertile
Bluelighter
- Joined
- Mar 31, 2022
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- 1,627
Do not take this personally but that is all a bunch of speculative nonsense. ( Huge hypocrisy regarding this theme. ) Benzos and Opiates are 100% safe. (Here we go again ... ) if you drink a pint of lager you might feel somewhat goofier, right ? If you do drink your body weight in lager you might just die. Yeah ?
I´ve always used , at times abused, benzos and (both ) opiates/oids simultaneously with no negative side effects at all (well ,besides ruining my personal life and making others around me miserable, subsequently absent as a consequence ) .
You might see me as the "The exception " ,happens I am "The norm " (NA/AA centers are there to prove it -majority of people in there ,are there for polydrug (ab)use issues ).
Not discrediting that study 100% for obvious reasons ,but the Big majority of people in here know perfectly well that , therapeutic doses ,it is perfectly safe to combine Opiates/oids + benzos ... a lot would even use 1st generation anti histamines and others ( again ,moderation and common sense ) to add to
the sedation/oblivion .
You just have to do your research and use common sense ( as much as possible that is. ). Plus, chances are your Psychiatrist ( or whoever writes your prescriptions ) will back you up on this. Mine certainly did when I appeared with "Sleeplessness " as a side effect to Buprenorphine. Wrote me a script for Oxazepam right on spot and told me when and how to take it - that is part of his job description if I´m not mistaken.
As for the Psychosocial aspects of it ... " Cases of air rage " and all that ... . Neither benzos nor Z drugs cure "bad manners " and other pre existing personality traits .
I apologize if that sounded personal since I´m hardly "shooting the messenger " in here . It´s just far too many years of , on and off, addiction ,and to such combos in particular ,to let that one slide ... ( that and endless hours ,flying from here to there , under the influence, witnessing "normal people " unable to control their alcohol, thus abusing others as the consequence , all this whilst I nodded away peacefully, oblivious to their antics
Take care .
Oh I can assure you that no personal offence was taken.
matt<3ketamine gave you a good counterexample.
People will read your post and make their own minds up about the reliability of you input. You have been frank and that is to be applauded.
fastandbulbous
Bluelight Crew
Personally, I'd say gross stupidity. Only reason I got to try pentazocine was some people who had a Rottweiler with bone cancer, found it growling nastily at fresh air and thought that we'll dodgy. She knew I had a huge interest in alteredstates, so she bough back either 4 or 5 scheduled for destruction. All bar two went down the outside toilet. All the terror of salvia without a hint of opioid. Now can't remember if it was quinalbarbitone or amylobarbitone sodium (vet euthanasia soln). Not sterile, tastedfucking hideous, but damned fucking nice effect, in lower doses (not Tony Hancock doses)
fastandbulbous
Bluelight Crew
Well death is pretty much the lowest common denominator! 
fastandbulbous
Bluelight Crew
Take until existential angst goes (one way or other!)
Survival0200
Bluelighter
It's usually pentobarbital.