Opioids DXM to boost Hydrocodone

[YEAhp]

Okay so I have heard of DXM boosting hydrocodone. How much does it take and you take it like 1hr before right. Also I only have these cough pills with 10mg of dxm, 325mg apap, and 2 other active ingrediantes. im assuming these pills are no good for this.

Also what are some other ways to boost Hydrocodone.
I heard good old mary jane does the trick but not too much.
Grape Fruit Juice... Heard bout this and it boggles my mind. I will have to try once cause im sure it could do no harm.
anything else besides more hydro or other drugs.

 

[laCster]

Marijuana doesn't potentiate, it synergizes. for you first time, take 60mgs atleast half an hour before you dose hydro. I think dxm goes well with opiates, though some prefer not to take any at all. I would explain what the difference between potentiation and synergy but I am on a smart phone.

So, 60mgs 30mins before, don't expect much though besides a duration of hydrocodone

 

[ErgicMergic]

^ 60mg is a bit much for a first time DXM-as-potentiator user, imo. I would use 30mg half an hour before an oral dose of opiates, this way you get a feel for DXM, which has psychoactive, stimulant effects, even at a non-dissociative dose. DXM's NRI and SRI effects can be uncomfortable to some.

Generally, 15-60mg are stimulant doses, depending on how many 2D6 enzymes you have to convert it in to the nmda antagonist prodrug, DXO, which is why some people feel strangely dissociated at doses as low as 45mg. Personally, I use 45-60mg half an hour before dosing opioid, 60mg if it is an opiate, and 45mg if it is an opioid like Kratom, which contains an NMDA antagonist alkaloid on its own.

 

[teological]

To help out laCster, SYNERGY (taking into account this post is about opiates) is when a substance works well with the opiate. So the opiate with the weed feels good because you are both stoned and getting euphoria at the same time. Amphetamines and heroin go well because they synergise well. They work on different nervous systems and feel good at the same time, but these examples are not the same as potentiating.

Potentiating is when a substance is usally taken before the opiate is administered so it actually boosts the opiate affect on you. For instance, Promethazine inhibits liver enzymes responsible for converting Codeine into Morphine, so it makes the Codeine more effective by helping it convert into more Morphine. Another potentiator is an NMDA antagonist like DXM (not taking it's psychoactive elements into consideration). An NMDA antagonist helps reduce tolerance/help maintain a low tolerance, in effect making your opiate stronger. This is potentiation.

The DXM is both synergy and potentiation because it is psychoactive in it's own right. You should take the required dose for a cough about 45 min before you dose your opiates to avoid the psychoactive elements of the DXM, which in my opinion can suck and make the opiate warmth feel way more spaced out and distant. Still, IMHO the boost to your opiate with DXM is not really noticeable...each their own. Also make sure the DXM is DXM ONLY, not with other active ingredients.

Grapefruit is a potentiator and should be administerd 45min before. Anta-acids to lower the PH level in your stomach is also a good way to help the duration of your drug (if taking oral doses). Tagamet, quinine found in tonic water and the list goes on. All similiar dosage timing. They can work, expecially if you use alot of potentiators.