• N&PD Moderators: Skorpio

Drugs inducing neuro-regeneration

jamshyd, do you actually know the answers or are you just asking someone specific for them ? because i think you are asking yourself there but not answering. lame.
 
No, I frankly don't know why I want to achieve a non-specific growth in neurons, nor do I understand what a few lost Purkinje cells translates into.

While you're at it, you might want to take a stab at explaining how, exactly, are Olney's Lesions (assuming they exist) are bad, aside from looking like holes when photographed, making them subject to aesthetic debate, but not much more...

My point? "Neurogenesis" seems to be the new "increasing serotonin" in its utter uselessness as an object of aspiration...
 
jamshyd, problem i have with neurogenesis is that im not sure at all what it actually happens. not like you have control of what neurons form and how they form or which region etc. i assume it can have detrimental effects YET the idea behind it is; that it might prevent, or help people with neurodegenerative diseases. do you think this can be possible ? if so, maybe its prolly more bad than good ?
anyway a lot of natural things cause neurogenesis, like sleep, exercise, ability to adapt in new surrondings etc. if those natural ways cause it, then i guess its practically safe and you can experiment with drugs that do it too, no ?
 


My point? "Neurogenesis" seems to be the new "increasing serotonin" in its utter uselessness as an object of aspiration...

we dont know what having more neurons will do to a person, surely different ways to cause it will affect different types of neurons in different ways. we cant yet know if this is bad or good but to blindly assume it is positive isn't really the best idea. the way that neurons send signals from one area of the brain to another is poorly understood and increasing the signal from one part to another (within a system) could be just as destructive as decreasing it can be (parkinsons). within a circuit one part can inhibit and another part can stimulate and this goes round in a weird loop, affecting an inhibitory part can cause stimulation and vice versa in places far away.

i personally think glucose metabolism in the brain has more to do with mental health isssues and how to go about improving them than new neurons generation will (try eating less sugar)

http://www.sciencedirect.com/scienc...8f34b7ff8e618aabf6196d79217d5441&searchtype=a

http://www.biologicalpsychiatryjournal.com/article/S0006-3223(00)00975-6/abstract

excercise etc. are probably fine, but ect is maybe pushing it a little bit
 
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No, I frankly don't know why I want to achieve a non-specific growth in neurons


I view the brain as analogous to a muscle in a way. Neurons are to muscles as tendons are to synaptic connections and strength of signals passing along them. If you use steroids (or increase neurons), but don't focus on increasing the strength of your tendons (or promoting synaptogenesis), you end up with many a health issue. Not to mention the problems associated with steroid use (eg related to cognitive enhancement, exacerbated mental health issues) that come along with all of that enhancement.

And not to mention the possible ramifications if you could increase neurons reliably, and enhance synaptogenesis, yet did not utilize this enhancement efficiently. What use would having all that excess do without proper stimulation to use it on. Extra horsepower, and you're stuck in traffic (or, extra brain power and you work 9-5 and come home to browse bluelight until you fall asleep).

The problem with enhancing brain power isn't the act itself, but knowing what to do once you get on that road. I'm sure of it.
 
^ Therefore, it appears to me that the only reasonable thing to do to keep the brain healthy is eating a reasonably-healthy diet and doing something that combines both fresh-air and a sense of awe. I think most people under-use their brain as-is.

To me this translates into saving all the money I'd have wasted on those "life-extension" chemicals and using it to buy a ticket to, say, Croatia or Lebanon where I can go for a hike in the mountains with a bag full of Mediterranean food :).
 
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