Drug combo tramadol with hydrocodone

[strgchris]

Hey everyone really just looking for experiences on this combo and if there are any significant interactions besides cns depression. I searched the web and can't find much out there.

 

[Johndoedoe.junk]

While I haven't had any personal experience with the combo, my wife has and she said the Tramadol interferes with the hydro making it less euphoric, although mileage does vary from user to user.

 

[Nether Animal]

The stimulant-like effects from the tramadol might indeed interfere with the hydro buzz.