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Drug anxiety and reaction to strange nerve on front shoulder just above left breast?

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theGirlWithBlueHair

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Okay so I just received cannabinoids and usually when I approach the high dosage end I tend to get some anxiety and chest pain and I have gotten this - and of course it is to be expected from this class of drugs - amphetamines, as well

Now I've discovered if you take your fingers, and rub in a circular motion, and rub the area just above your left breast by your crevice of your underarm and going in about 2 - 3 inches in and the nerves around that area, it helps the pain and removes any anxiety, returning my high to a nice comfortable relaxing state.

I can tell it's a nerve effect because when I hit the right spot I can feel a strange sensation that goes down a nerve in my arm and tingles in my hand.

PS I have neuropathy. I know what nerves feel like. This eliminates all anxiety and fear from drugs. HOW does this have CNS effects and potentiate the high and immediately abolish any negative effects?

What is going on with the nerves and my nervous system?

There is some interaction; it is not placebo. You hit something in there as you can physically feel it, and it does something centrally.

Does anybody know or have any experience?
 
theGirlWithBlueHair said:
Okay so I just received cannabinoids and usually when I approach the high dosage end I tend to get some anxiety and chest pain and I have gotten this - and of course it is to be expected from this class of drugs - amphetamines, as well

Now I've discovered if you take your fingers, and rub in a circular motion, and rub the area just above your left breast by your crevice of your underarm and going in about 2 - 3 inches in and the nerves around that area, it helps the pain and removes any anxiety, returning my high to a nice comfortable relaxing state.

I can tell it's a nerve effect because when I hit the right spot I can feel a strange sensation that goes down a nerve in my arm and tingles in my hand.

PS I have neuropathy. I know what nerves feel like. This eliminates all anxiety and fear from drugs. HOW does this have CNS effects and potentiate the high and immediately abolish any negative effects?

What is going on with the nerves and my nervous system?

There is some interaction; it is not placebo. You hit something in there as you can physically feel it, and it does something centrally.

Does anybody know or have any experience?
Click to expand...

If the point you are describing is just above the collarbone, at the left side of the base of the neck, it is called the brachial plexus. Stimulation of the brachial plexus causes feedback to all the nerves connected. The feedback may provide some type of anxiolytic action.

Of note, a strike to the brachial plexus can cause unconsciousness -- it is a target is some types of martial arts.
 
No. That is nowhere near it. Just below the shoulder, by the crevice above the left breast. Around that area, and up to two to three and a half inches in. What you described is far from it.

Also on the bottom left side of my left breast, if I rub there it stimulates a nerve that reduces chest pain as well. What is this? I can feel nerves react there, but only when high and there is too much chemical causing the pain...?
 
The upper one is above the breast by the corner around the corner of the should above/near the corner of the crevice formed by the arm and torso. The other one is by just above left breast and it activates a nerve that is likely directly over your heart that seems to have to directly affect your heart as well.

I did it right now with cannabinoids in me and it mitigated chest pain and kind of gave of revitalized feeling. What is this? It is a nerve thing as I can feel nerve-type effects going on and it spreads through nerves, through my chest and shoulder and arm, and my hand.

I do not make a habit of this.

It also kills anxiety and sort of dulls/ruins the high a lot, so how is it CNS active - me rubbing my body?
 
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This happens mostly when I rub the area around the breast on the left side by the area of the heart so there must be a nerve there so it is neurological - and being cardiovascular as well maybe - and since it helps with chest pain, kills anxiety yet almost kills the high/really dampens it - it is indicative of of nerve activity - also responsible for causing CNS activity.

So what could be going on?
 
You might have thoracic outlet syndrome and costochondritis from chest breathing, the pec minor (armpit area) and other inhalation muscles are well known to cause such issues, subclavius/1st rib is also an area where nerves can be compressed. I think shugenja is right about the brachial plexus, it's something I've had a lot of issues with personally as well.

I'm a bit confused on your description of the location though - if you could tell us something like "it's between the first rib and collar bone in about the middle of the chest laterally" then that would be more helpful.

Nerves consume more than 20% of the bodies oxygen and they have tiny arteries running inside of them, when they get compressed their bloodflow is reduced and they get cranky - sympathetic mediated constriction can worsen bloodflow as well as increase chest breathing and muscle tension.

I would examine thoracic outlet syndrome and stretch pec minor and scalenes for starters. The office tests for thoracic outlet syndrome generally involve checking for diminished function with the arms held high above the head as if you were reaching for the ceiling.
 
No it's some type of natural nerve thing in the body as there are "nerve points" if you look for them you should try to do it, the motions I describe on the front shoulder part but pushing in whilst doing in and moving around too.

those of you who are high on marijuana it will work a lot better.

And breathing is fine.

Location: Above the left breast to the top of the shoulder, just to about the top of the left of the crevice formed between the arm and the torso, and from the start of there to about 2 - 3 inches in. Spot on description you can follow with your hand.
 
I'm really sorry lol I'm still having a very hard time with the location - can you tell me the muscle/nerves located in that area? But we're not talking about the armpit or pec minor are we?

Do you ever get the ASMR feeling? (Wiki explains ASMR)
 
That isn't what it is.

Cotcha Yankinov said:
I'm really sorry lol I'm still having a very hard time with the location - can you tell me the muscle/nerves located in that area? But we're not talking about the armpit or pec minor are we?

Do you ever get the ASMR feeling? (Wiki explains ASMR)
Click to expand...

It isn't exactly a euphoric feeling and occurs when not high - I can get a response right now - too. It's a physical thing, with nerves, but not what that's describing.

What I meant is that it seems to stimulate the heart.
 
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It does not feel good; it is rather odd and uncomfortable feeling. But I feel good afterward. It has like a good afterglow But it ruins the high. And it kills the chest pain too. both spots do
 
Beta blockers - metoprolol, which is beta 1 selective - block the nerve feelings I get in my hand from this.

Epinephrine possibly involved and beta receptors and adrenergic and cholinergic innervations in the blood vessels?

Explains it...?

Cannabinoids directly inhibity cholinergic transmission and increase adrenergic activation via GABA inhibition, which is how they cause chest pain - immediate release and turn over of acetylcholine causes this directly.

So this explained mechanism of action could make sense for the symptoms I listed, as least with the drug described.
 
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I would wiki vagus nerve and valsalva maneuver - valsalva maneuver is known to have profound effects on the heart and as I recall works by stimulating the vagus nerve. And I do believe the parasympathetic nerves mostly use acetylcholine.
 
What does the valsalva maneuver have to do with what I explained? I'm rubbing parts my body. That nerve thing makes sense. Thank you! What about the epinephrine and metoprolol: what do you think of that?

How does it ruin the high though, it like aborts it, even right after I take a massive hit if I do it? Release of acetylcholine and rebound of cholinergic activity? How would it do that in the CNS though and how would it reverse CB1 activity and displace the cannabinoid at the receptor/antagonize its effects?
 
Valsalva maneuver can alter pressure on nerves within the body and the spinal cord, especially very upper craniocervical junction.

I think sympathetic activation is important for rewarding effects and parasympathetic stimulation might diminish that or affect neural circuitry in some way. There might be some way for afferent spinal cord pathways to affect a high.
 
hello once again blue haired girl

I'm reading the thread and I'm extremely surprised no thought of Chinese medicine like acupuncture which may seem to some as non legit but It has science behind it while not completely recognized by the scientific community I think it has real value spiritually and scientifically in terms of nerve points,blood circulation,and endorphins (dopamine Epinephrine ect)

it could be the endorphin effect kinda like the choking game (where you choke another person almost to the point of being knocked out then waiting for the feeling to comeback with a euphoric head rush) or like when you hit your funny bone then the feeling of it coming back I think its a possibility if its where I'm thinking (is it the area of the arm where if you do ALOT of push ups it will be sore for a long time afterward or in other words the crevice between where your shoulder connects and where your breast is?)

if so maybe your limiting blood flow and then when it returns it could flood endorphins to the brain

any thoughts?

-streetcow
 
No endorphin activity as it causes more chest pain and then gets rid of it. It is causing physical sensations more than mental ones: it's main mental activity is killing the high.
 
I have a feeling that this is little more than a psychological trick used to distract attention from the negative effects you're experiencing. The Scientologists call this sort of stuff "touch assists" and while their explanation for the underlying mechanism is a bunch of horsecrap, the fact remains that focusing one's attention on a stimulus away from what's bothering you can provide relief for all sorts of symptoms. The mind is a powerful thing and it's well known that stuff as simple as meditation/mindfulness can produce major improvements in mood.

Just 'cause there's an observable effect doesn't mean you can discount it from being a placebo, though. "Placebo" doesn't mean a treatment that has no effect entirely - you can, for instance, see reliable improvements in diseases/ailments using placebos in some cases, probably due to the fact that something as simple as intention to treat can have strong effects. That's why we compare medications against placebo and not against no treatment.
 
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