Droxypropine

[Ham-milton]

Except that it wasn't a question.

 

[Smyth]

I'm not really interested in getting into the pedantics.

If you look back at my posts, I was clearly interested in establishing to what extent this is of real-world significance or if it is another pointless theoretical spiel wrapped in fantasy like most of the other hapless time wasters.

 

[haribo1]

Ketobemidone without that meta -OH on the phenyl ring is very weak. The trick of forming thr quat to remove the other N substituant is a good one. A bare NH would be better since a CH2-CH(OH)-CH2- phenyl could be added which should be powerful and would be legal.
That quat nitrogen trick is so cool. Replace the N-methylcyclopropyl off nalfemene with a methyl for x80 morphine fun. Acetylate for even more bang per buck...

 

[haribo1]

BTW, do you have access to droxypropene, or just a strong desire to do some mental synthesis?

 

[Ham-milton]

Again, the rule about suppliers...


Mostly I'm wondering duration of action (ie: how many times would one need to dose a day), potency and equivalency. And toxicity. Toxicity would be a major issue.

It's something I'm really considering. More than I ever thought I would have.

I'm confused about how that would be legal? (You're talking British laws, I take?)

 

[haribo1]

the potency of the none meta -OH of ketobemidone is 0.3 times pethidine so it's SOOOweak...

 

[LuxEtVeritas]

that's is what i though and one reason why in regards to this compound i assumed it is negligible in the effect postulated