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  • BDD Moderators: Keif’ Richards | negrogesic

Stimulants Does IV methylphenidate give bellringers?

bluecollartweeker

bluecollartweeker

Bluelighter
Joined
Nov 7, 2023
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224
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Canada
I Love the tinitus that comes alongside the rush of IV cocaine, dimethocaine, and dichloropane. I love that ring and rush but i only have ritalin now until i can salt back some more hard. I have a srip for 90 10mg IR monthly and i have a tolerence high enough that i sometimes take 120mg in a day. I have real chemistry experience and can seperate and isolate methylphenidate, ive done similar chemistry ordeals to grow crystals of bupropion so dont give me any lip about talc.
WIll a shot of 30-60mg ring my bell?
 
No one can say. Everyone is different and what someone else would need has nothing to do what you would need
 
Well i tried 3 times, with very carefully extracted, multiple filterd 50mg/cc shots in my bicep, forearm, and calf intravenous, and didnt get much more than a whiff of the memory of euphoria. Cant beleive this didnt work on me, and now im out 15 pills. I cant fucking wait till i can get more cocaine or DMC im in such a fix im so pissed this was a flunk.
 
Methylphenidate (Ritalin) is roughly 2X more potent than Cocaine at the DAT (ED-50) effective dose to inhibit 50% of DAT dopamine transporters (which is required to induce euphoria)

Ritalin DAT>NET
Cocaine DAT>SERT>>NET

Both are nearly identical as “Inverse Agonists” at monoamine transporters, causing their increase by transporter inhibition, as well as their release through other MOA different from the classic Amphetamines.

Ritalin orally taken with a meal speeds absorption, and consumption of Ethanol increases the active d-threo-MPH by 40% significantly enhancing the euphoric pleasure of Ritalin.

Injecting Methylphenidate is MUCH more potent than oral obviously……a CWE to remove all the excipients/bulking agents and just have pure MPH HCL powder to inject

Methylphenidate (Ritalin) and Oxycodone (Oxy-IR) were the only two drugs in my entire lifetime to ever give me true euphoria. Overwhelmingly happiness, dopaminergic & opioid euphoric bliss. Ritalin is an amazing dopaminergic stimulant and Oxycodone is a non sedating slightly stimulating mu-opioid agonist …both Extremely Euphoric & Pleasurable
 
Dextro .45 said:
Methylphenidate (Ritalin) is roughly 2X more potent than Cocaine at the DAT (ED-50) effective dose to inhibit 50% of DAT dopamine transporters (which is required to induce euphoria)

Ritalin DAT>NET
Cocaine DAT>SERT>>NET

Both are nearly identical as “Inverse Agonists” at monoamine transporters, causing their increase by transporter inhibition, as well as their release through other MOA different from the classic Amphetamines.

Ritalin orally taken with a meal speeds absorption, and consumption of Ethanol increases the active d-threo-MPH by 40% significantly enhancing the euphoric pleasure of Ritalin.

Injecting Methylphenidate is MUCH more potent than oral obviously……a CWE to remove all the excipients/bulking agents and just have pure MPH HCL powder to inject

Methylphenidate (Ritalin) and Oxycodone (Oxy-IR) were the only two drugs in my entire lifetime to ever give me true euphoria. Overwhelmingly happiness, dopaminergic & opioid euphoric bliss. Ritalin is an amazing dopaminergic stimulant and Oxycodone is a non sedating slightly stimulating mu-opioid agonist …both Extremely Euphoric & Pleasurable
Click to expand...
Do you think it must be a tolerence issue then, that it didnt work for me? I.V 4-mmc still works at 100+ mg i love that. Dimethocaine i actually still prefer over cocaine and found it more addictive
 
Maybe just take 100mg of IR Methylphenidate orally…..with a light healthy fatty meal (toasted egg sandwich, cooked ham, little cheese, chased with OJ containing 100mg of pulverized MPH powder)

then make several spirit cocktails 40% Ethanol Rum/Gin, little ginger ale and OJ ….2.oz each drink. After the 3rd drink in 45min-1h the onset of dextro-threo-methylphenidate will be Significantly more robust, faster acting, harder hitting, and significantly more euphoric & pleasurable.….a higher AUC & C-Max / T-Max

40% higher d-MPH (Focalin) concentrations due to ethanol DDI with racemate Ritalin

Try this method…..it is VERY effective. Sure it isn’t a bellringer (which I’ve taken 50+ speedballs & bellringers) but oral ROA shouldn’t be underestimated. Obviously a slower onset as it enters the bloodstream much slower, but this method was documented in a medical journal with study participants v.s. controls ….and I’ve done it myself over 100 times and I concur with the study findings

Very euphoric & pleasurable

Also very interesting, another medical journal study with cocaine dependant individuals, they were injected intravenously with either Cocaine or Methylphenidate (Ritalin) and most had difficulty distinguishing which drug they received….which is odd because Cocaine has VERY prominent Serotonin after Dopamine….with Norepinephrine lagging behind…..where as Ritalin has Dopamine 3-4X greater over Norepinephrine, with negligible Serotonin properties.

My beloved I.V. injection was….

Heroin - 4 parts
Cocaine - 1.5 parts
Ketamine - 0.5 parts
 
I made an extraxt of 100mg and cooked it down to 1cc and slammed it, felt the warm hug like bliss but no instant rush, ill probably stick with other ROAs and save my veins for coke and mephedrone
 
nznity said:
You're gonna die young if u keep doing this. IV cocaine almost destroyed mu life
Click to expand...

I don’t know your situation, but it fucked my life up significantly. I was really close to dying. The amount of damage I did to myself, and everyone I loved, makes me sick to my stomach :/.
Hope you’re doing well these days
 
bluecollartweeker said:
In vivo conversion to ethylphenidate
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I'm not sure that you make the active isomer of ethylphenidate via transesterification.

The paper below refers to the presence the inactive (-) isomer of ethylphenidate in post mortem blood samples, and compares (+) and (-) ethylphenidate and methylphenidate, showing that the methylphenidate is more potent, but both are primarily active at DAT.

The fact that (even the correct isomer of) ethylphenidate requires a higher dose than methylphenidate is the nail in the coffin, as it is being metabolized into a weaker compound.

 
Skorpio said:
I'm not sure that you make the active isomer of ethylphenidate via transesterification.

The paper below refers to the presence the inactive (-) isomer of ethylphenidate in post mortem blood samples, and compares (+) and (-) ethylphenidate and methylphenidate, showing that the methylphenidate is more potent, but both are primarily active at DAT.

The fact that (even the correct isomer of) ethylphenidate requires a higher dose than methylphenidate is the nail in the coffin, as it is being metabolized into a weaker compound.

Click to expand...
Oh thats fascinating i gotta read into the pharmacodynamics
 
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