N&PD Moderators: Skorpio | someguyontheinternet
when one considers that NBOMe-2C-C is about 100 times more potent than 2C-C, then an educated guess would be that NBOMe-DOC could be active in the 10 microgram range.
when one considers that NBOMe-2C-C is about 100 times more potent than 2C-C, then an educated guess would be that NBOMe-DOC could be active in the 10 microgram range. that is only speculation, of course, but it still gets my imagination going. even think of its dragonfly analogue, or what happens if you conformally restrict it (a la TCB-2), or if you replace the chloro by a trifluoromethyl group... sorry, my fantasy goes trough with me.
According to Erny: "NBOMe amphetamines are about ten times weaker than their phenylethylamine counterparts."
NBOMe-2CB-Fly is a known compound and has very high binding affinity at 5HT2A, though seems to be a fairly weak partial agonist.
Could you mention what study you are thinking of that showed it to be a weak partial agonist?
And as nuke notes, alpha methylation of the phenethyl portion dramatically reduces both affinity and efficacy, so NBOMe-DOC will be weak at best.