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DOB vs DOI?

fairnymph

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Jan 16, 2000
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It is possible that I may have a chance to sample one or both of these substances and I have a few questions.

There is alot of comparison between DOB and 2cb that I have seen, especially on erowid. I particularly DISLIKE 2cb and do not tolerate it well (very negative body load: temp problems, nausea, muscle tension, GI issues). I also seem to be highly sensitive to it. Furthermore, DOB reportedly has very similar side effects to those I experienced on 2cb. As a result I am hesitant to explore DOB, and I suspect I have developed a sligthly irrational fear/dislike of brominated compounds.

The DOI seems more appealing to me, but there much less information about it than for DOB. If it's worth anything, I've also experienced 2ci, with minimal effects overall and no noticeable negative effects.

Bottom line, I fear the body load with either of these substances and at this point in my psychedelic exploration I'm not sure I want to suffer through more physical discomfort. 2cb, for me, was not worth the discomfort at all -- yes, there were some visuals, but for me no sparkle, nothing special about it, no insight. If DOB/DOI has truly outstanding potential for insight, I would be more willing to deal with discomfort.

Thoughts?
 
Thoughts? Not really, you probably know that DOB is just the isopropylamine(amphetamine) version of 2c-b. So, if I had had bad reactions to 2c-b, I'd be very hesitant to take DOB - or even DOI, since it's like DOB, only with a slightly heavier halogen (iodine).
 
^You are right about it's heavier halgon. But still, 2c-b and 2c-i are very different in effects. So, I would go with DOI if I have chance and If I'm you. Maybe there's something about bromine that makes thees negative effects on you?
 
Yeah, it's too bad that even though DOI is one of the most studied exotic chemicals (I remember it being used in positron emission topography, since it's easily radioactivated or something..), there's not really very much qualitative information about it. Maybe it's not available for too many people - I know I've never seen any.
 
DOB and 2c-b are and are not similar. On the bodily note, of three who took it 2 normally are not bothered at all by 2cb, 1 is. None of the group had significant issues with DOB. The onset was somewhat disturbing not because of anything in particular, but instead because of its eerieness, its energy, etc. The whole experience reminds me of a 2c-b experience MERELY stretched out across 24hrs with added energy. It changes the character somewhat, but not all that much. So in that vein you might be hesistant to take it.

... On the other hand many of the reports on DOI mention even more extreme stimulant push, body load, and less psychedelic activity. Then again very very few people have done it so it is all speculation, but either way it is a big choice as once you take one of these you will be stuck for a long long time.

One other thing, DOB will make you rather hungry. I have a high metabolism and had to eat every 15 minutes, it was bad. I would prep for that and have lots of easily prepared food around. Good luck
 
oh one more thing, the bromine or iodine or heaviness wouldn't be the problems, it would be the bromine in the structural configuration it is in (which DOB and 2c-b share). Once you leave the 4-X-2,5-dimethoxy-pea formula the bromine and iodine would operate differently in your body.
 
DOI

If you didn't find the stimulant edge of 2C-I too uncomfortable, then I would say starting with a low dose of DOI (less than 1mg), should give you some sort of idea as to how your body will react to a larger dose. As for the DOB, I would be inclined to avoid it in your case, but if you're really, really curious, then take a 250ug (0.25mg) dose to monitor how your body reacts, but also make sure you have a decent supply of a benzo (pref long acting like diazepam), in case things take a turn for the worse.

Although there is some correlation between 2C-B/DOB and also 2C-I/DOI, the amphetamine derivs have a less limited range of effect w.r.t receptor binding (DOI is used for PET scans as it acts purely on 5HT2A receptors). Also, the amphetamine derivs are a lot more resistant to metabolic breakdown, and as a consequece last a lot longer than the eq. PEA derivitives.

PS. I'm also quite envious of your access to these two compounds! Ah, I can but dream
 
I do not think there is as much of a correlation between the effects of 2CB and DOB as their structure would indicate. For example thing of the difference in effect between 3,4,5-trimethoxy-phenethylamine and 3,4,5-trimethoxyamphetamine.

Hopefully in 6-12 months I'll be able to answer this question for you (I can't exactly fit 2 trips of this caliber in my life any sooner than that). But for now the best person to ask would be: http://www.cognitiveliberty.org/shulgin/
 
all I can say, is that from close friends of mine who've tried DOB, it was the most intense (in a good way) trip they've ever had. like MDMA and LSD x 20, for at least 24 hours if not more. They could see the soundwaves pullsating from the speakers (they were at a club) and all they could do was lay there in intense euphoria.

sounds to good to be true to me, but who knows.

all I know is that I wouldn't mine sampling some :)
 
DOB and DOI are quite similar and dissimilar at the same time. The same way that 2C-B and 2C-I are similar yet not.

I usually find that 2C-B and 2C-I are lovely friendly compounds, whereas their amphetamine counterparts have a much more serious overtone to them.

From my experience DOI is less euphoric than DOB but has a bit more depth. DOI is almost a depressant of sorts. DOB has more anti depressing/sensual qualities. DOI is good for giving you a clear head, cold focus more like meth-amphetamine. Whereas DOB has a softer feel to it and is perhaps more "fluffy".
 
^^^Ill keep that in mind. Still, I wonder how methamphetamine-like either can be, based on their selectivity for 5-HT2A receptors over dopamine and serotonin transporters.
 
on nausea: 2cb (which i really like) usually messes with my stomach pretty badly during the comeup. dob did basically the same thing, but less intense and over a longer timescale...instead of battling severe nausea for 15min before giving up and making myself vomit, as with 2cb, i spent a good 90min battling moderate nausea on dob before getting abruptly and violently ill. in both cases i felt better immediately afterwards.
 
Im glad to see these compounds gaining wider acceptance. I remember doing morning paper rounds 9 years ago. I read 'dangerous new drug 33 X stronger than XTC being sold to ravers'. Everyone was too scared to take something 33X stronger than XTC. But the fact of the matter is it is a stronger drug so you take less. It lasts about as long as amphetamine.

Pros of DOB over amphetamine: Can still eat, can still sleep. DOB is not hallucinogenic on the lower end of the dosage scale.

Conclusion: DOB is better than amphetamine.
 
P.S. if you dont want to go in for a drug as brutally potent and dominant as DOB, DON is the 'black & white' version of DOB. DOI is DOB's demented brother. Choose whichever you prefer, I would still say a CLEAN dose of DOB in the morning is your best bet. Really make sure it is analytically pure though. Dont worry 2 much about wasting product when it is of this order of potency.
 
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It definitely lasts a LOT longer than amphetamine...a LOT longer.

My fiance enjoyed his experience with DOB, as did his friend. No bad effects for them but then they don't get any from 2cb either.

Even with a bunch of downers, however, only one of them could sleep...the other has been up for over 24 hours.
 
Hmmm, I wonder this also... I never found DOI to be demented. DOI is less 'pleasurable' than DOB, but it can also be very fruitful especially in meditation and introspection. It is less debilitating than DOB, in that you can still talk and interact on DOI, with DOB I think your much more likely to be floored.
 
dob definitely lasts longer than straight amp - i had the shortest dob experience of anyone i have ever talked to and it still lasted a good 18 hours - and i don't think i was baseline foir another 4 or so.

and ronald - don is NOTHING like dob.
 
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