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Do other drugs become less euphoric after losing magic?

Jackie Chan

Jackie Chan

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Nov 16, 2010
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Do other drugs become less euphoric after losing the mdma magic?

Well, long story short, I abused mdma when I was in high school and now I've completely lost the magic. I still take mdma from time to time in the hopes that the magic will somehow return but it never does.

Anyways, I've noticed with certain drugs, like shrooms for example, it's impossible for me to get any euphoria from them. I never tried shrooms before I lost the magic with mdma. Whenever I have eaten shrooms my body feels cold and really uncomfortable. I also get really depressed and anxious on them. I basically never experience any of the positive effects that I read others have. I do get f'ed, but never in a good way. Zero euphoria or any type of good feelings.

I've read that a lot of the good effects from shrooms are due to the effects it has on serotonin. This is why I think my past mdma use has made it impossible for me to have a good trip on shrooms.

I was wondering if other people who've lost the magic have noticed that other drugs that affect serotonin, aren't as euphoric or enjoyable anymore?
 
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Both mushrooms and MDMA use serotonin so that may be the cause of the lack of euphoria.
 
i use to be a daily heroin user but i stopped and after a period of taking mdma consistently and losing the magic, i no longer find opiates euphoric at all. opiates dont effect serotonin but i think i just associate feeling awesome with mdma now, so i find opiates much less euphoric than i use to.

personally i dont find mushrooms euphoric at all. if youre looking for psychedelic euphoria, lsd is the way to go. but yea even that is incomplete without mdma.. thats just my personal opinion though.
 
theotherside26 said:
Mephedrone/methylone can lose the magic if you use them more often than once a week. MDMA loses its magic for me if I use it more than once a month.
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I meant do other drugs become less euphoric after losing the mdma magic, even if it's ur 1st time doing those other drugs.

For example, drug z creates euphoria by affecting serotonin. Let's say I've never tried drug z before. I have however abused mdma and lost the magic with mdma. After losing the magic with mdma, I try drug z for the first time. I get almost zero good effects from drug z because the serotonin system in my brain is damaged due to my past mdma use.
 
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I've found that regaining the magic isn't just about time off from mdma, although that's obviously a key factor. Other factors that may be less important before you've lost the magic become bigger issues afterwards.

Besides time off, who you're with when you roll, the music you're listening to, the environment and your state of mind going into it all need to be dialed in. These are more important IME than getting super strong pills (they should of course be clean).

Take time off and come back and try rolling again on occasion, say once every few months or whatever. Eventually, I think the 'stars will be aligned' and you'll have the cathartic experience you're looking for.

As far as other drugs being less euhporic after prolonged mdma use, I haven't found this to be the case. I think you're just basing it on mushrooms, which aren't necessarily all that euphoric anyway IME. Despite the claim that they may release seratonin, it's not on a level anywhere near mdma, so I don't think you'd notice it anyway.
 
LSD was not euphoric for me. Not even when I took ecstasy to MAKE it euphoric. Nope. Swallowed any euphoria and replaced it with mindfuck.
 
Mushrooms aren't euphoric for me either, but that's just how they are with me. LSD, Mescaline & all sorts of other psychedelics are very euphoric. Other MD drugs & cathinoes are really great too.

It's been a year or two since I've done MDMA, it was pretty decent the last time (after a 8 month or so break), so hopefully if I try it again it'll be almost back to normal.
 
once you lose the magic for good your serotonergic system for all intents and purposes is pretty shot, so any drug that involves serotonin will obviously be affected.

Opiates DO involve serotonin (this is not widely known) and its necessary to have some working receptors (not many) to get the strong euphoria associated with opiates, although the relaxing effects should still be active as opiates bind to receptors all over the body and not just in the brain.

I have lost all analgesia and euphoric effects from opiates as a consequence of mdma.
I have lost almost all euphoria from alcohol (it just feels dirty now).
I have lost the ability to enjoy weed.
Amphetamines now make me psychotic (likely due to no serotonin inhibiting dopamine release).

So in conclusion, the serotonin system plays a strong role in almost all drug euphoria and if it is damaged you will suffer the consequences, that being any drug that affects serotonin will be down graded substantially.

Anyone else loss opiate euphoria from mdma, im curious.

Curiously, the only thing that can bring back serotonin receptors and axons/dendrite growth once you have completely destroyed your serotonin system is electroconvulsive therapy!! (without proper terminals and axons to act on all antidepressants and ssris are useless).
 
bben said:
Anyone else loss opiate euphoria from mdma, im curious.
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I recently tried kratom, took 10 grams on Saturday. I don't have much of a tolerance to opiates, and while I did get a buzz from it that lasted hours, there was no euphoria at all. I basically got the buzz, but I also felt depressed and anxious on it. I definitely didn't experience any of the euphoric effects I've read others experience on it.

But with codeine, I do get euphoria (never tried it before losing the magic so not sure if it would've been more enjoyable before losing the magic.)

I've only tried weed, alcohol and cigs before I lost the magic with mdma.

Weed has definitely been less enjoyable after losing the magic, but I still get positive and euphoric effects from it.

alcohol is also still enjoyable but not as enjoyable as it was before I lost the magic.

I think the reason I can still enjoy weed and alcohol is that they both affect dopamine.
 
Jackie Chan said:
I recently tried kratom, took 10 grams on Saturday. I don't have much of a tolerance to opiates, and while I did get a buzz from it that lasted hours, there was no euphoria at all. I basically got the buzz, but I also felt depressed and anxious on it. I definitely didn't experience any of the euphoric effects I've read others experience on it.

But with codeine, I do get euphoria (never tried it before losing the magic so not sure if it would've been more enjoyable before losing the magic.)

I've only tried weed, alcohol and cigs before I lost the magic with mdma.

Weed has definitely been less enjoyable after losing the magic, but I still get positive and euphoric effects from it.

alcohol is also still enjoyable but not as enjoyable as it was before I lost the magic.

I think the reason I can still enjoy weed and alcohol is that they both affect dopamine.
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Sure most drugs do still give some euphoria through dopamine I just feel its substantially downgraded, in particular with opiates for some reason.
 
The axons are not completely gone though. If they were you would be miserable, not be able to sleep, and your appetite would be irregular. Try taking some 5-HTP on a daily basis. Also, look into some brain drugs i.e. any racetam or centrophenoxine which is a derivative of DMAE. I find weed not enjoyable because i don't like the high anymore. I stooped smoking way before I rolled. I think to much when I am high on weed, and it intensifies everything. Like if my back hurts I notice it more. I am super sensitive to all drugs period. I have been rolling for going on 12 years on and off, and the magic is still there for me.
 
warmachine22 said:
The axons are not completely gone though. If they were you would be miserable, not be able to sleep, and your appetite would be irregular. Try taking some 5-HTP on a daily basis. Also, look into some brain drugs i.e. any racetam or centrophenoxine which is a derivative of DMAE. I find weed not enjoyable because i don't like the high anymore. I stooped smoking way before I rolled. I think to much when I am high on weed, and it intensifies everything. Like if my back hurts I notice it more. I am super sensitive to all drugs period. I have been rolling for going on 12 years on and off, and the magic is still there for me.
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You just defined tons of former mdma users. People often dont realize that losing the magic with mdma usually means losing the magic with everything in life.... thats a large trade off for a few months fun.
 
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bben said:
Anyone else loss opiate euphoria from mdma, im curious.
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I tried oxycodone for the first time last night, ate 4 percocets which is 20mg of oxycodone. The thing is, even I have low tolerance the 20mg didn't provide me with much euphoria. There was a strong buzz, but I didn't get any of that warm happy feeling I read about.

I'm not positive though if it's due to my past mdma abuse cause I never tried opiates before I lost the magic with mdma. I still feel like I damaged parts of my brain from using mdma too much and now my brain just isn't capable of producing the euphoria other drugs like oxycodone give most people.
 
Just thought I would drop by to let you know OP that there is no answer to your question because there is no such thing as "losing the magic". Not really magical - just a drug inducing a reaction in your brain that doesn't have some arbitrary finite limit influenced by an "abuse" period that makes up maybe 1 or 2% of a human beings entire lifespan.
 
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