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Dmaa bzp & mdma

Genetic Freak

Bluelight Crew
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Would consumption of 30mg DMAA & 50mg BZP several hours prior to 150mg MDMA consumption, have an impact on the action of MDMA..?
If so why..

Your thoughts pls....
 
well dmaa is as good as useless, thats a low dose of bzp too so i doubt it'd do much. Seriously dont bother with the dmaa its just rubbish, bin it!
It may add a slight more speedy feel to it, but dont expect too much!
 
I would advise anyone not to mix piperazines with MDMA.

They both attack / inhibit the CYP2D6 enzyme.

A nasty drug>drug synergy happens

If you happen to be an unlucky person like a few of us are BZP+MDMA = long term comedown.

Its a rare occurance but quite a few people take mdma for years and are fine.

They make this cobo and they get messed up.

Personally I would ditch the pipe and just take the MDMA.
 
I would advise anyone not to mix piperazines with MDMA.

They both attack / inhibit the CYP2D6 enzyme.

A nasty drug>drug synergy happens

If you happen to be an unlucky person like a few of us are BZP+MDMA = long term comedown.

Its a rare occurance but quite a few people take mdma for years and are fine.

They make this cobo and they get messed up.

Personally I would ditch the pipe and just take the MDMA.

That's what I was looking for... MDMA is first metabolized by CYP3A4 (N-demethylation) to MDA, both are then metabolized by CYP2D6.

So if CYP2D6 is inhibited, will this slow metabolism.? If metabolism is slowed, does the effect of the drug last longer.? Is the effect weakened..?
 
it causes the worst comedown of your life, read some of the posts in the thread about mixing bzp with mdma and see most of the people there have terrible comedowns lasting on average of 3-6 months
 
it causes the worst comedown of your life, read some of the posts in the thread about mixing bzp with mdma and see most of the people there have terrible comedowns lasting on average of 3-6 months

I didn't experience a severe comedown, but did supplement with 5-HTP 3-4 hours after MDMA plus a strong multi-vit and anti-oxidants, plus 5-HTP for several days after....

If anyone could explain what happens when both are metabolised by the same enzyme CYP2D6, means as regards to the strength and effect of the MDMA I'd be grateful.. Thanks..
 
what about having some DMAA a few hrs (4hr+) before the MDMA (just for the speedy effect, like a psychological acclimatiser). Would the DMAA interfere (ie, inhibit) the MDMA?
Obviously if it has a potentiating effect that's just icing on the cake lol.
 
There isnt a lot known about DMAA itself in the first place. I doubt it would have much of a potentiating effect seeing as DMAA is next to useless, but I can't comment on that because I have never combined the two and wouldn't. The stuff is banned now anyway, I would just chuck it - whenever I used it I helped me focus a little bit but it felt wierd and the comedown wasn't worth the "high" that it gave.

In terms of combining Piperazines with MDMA, its be known to cause horrible comedowns. I personally don't think that the reason for this is that they both compete for the same enzyme because a large amount of the MDMA is actually excreted unchanged. If you lack the CYP2D6 enzyme, which some people do, or it is blocked (due to piperazines or whatever agent is competiting with MDMA), it won't so much make your roll potentiated or roll harder, it will most likely just increases its duration a bit if anything.

The reasoning behind that is MDMA tolerance builds extremely fast. Say you bomb 100mg, you come up, you peak, your peak is slowly dropping off then you start comming down... Your blood MDMA levels will still be almost as high as what they were at the "peak", say you drop another 100mg, your blood levels rise even further and are probably for examples sake 80% higher than what they were at your first peak, yet you will not have a peak that is as good as the first one even though blood levels are almost double, again it is due to rapid tolerance.

Essentially blocking the metabolism of MDMA to achieve a better roll is the best part of pointless because of rapid tolerance build up. There are other ways to potentiate MDMA, but if you have your head on straight you would know not to go down that route as chances are you will wind up dead or left with permanent severe damage.
 
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