Dissociative Tolerance Question

[ElScorcho420]

I have never used Ketamine before, but I am going to have a very nice personal amount very soon.

I used MXE between four and two months ago pretty frequently, but in somewhat low doses. By the end of the two months, I could barely feel 25mg, and I required 60mg to feel dissociated. That special euphoria and psychedelic insight that I had the first few times was not there. I loved MXE, but I didn't really feel like buying more and getting my tolerance too high.

I have also been using nitrous oxide recently, not too much, maybe a couple packs of chargers in the past few months. I don't have much of a tolerance, but like with MXE, the high is not nearly as "psychedelic" as the first few times. I only use it now during the peaks of psychedelics, which is once or twice a month.

I used DXM at 300mg once under the influence of ambien, about one month ago. Don't remember anything, never would have taken it if I were sober. For those of you who have experienced Z-Drugs like zolpidem: 8(

I have not used any dissociatives since the DXM a month ago, except for nitrous oxide maybe once or twice.

My question is: In your personal experience, for someone who has an NMDA antagonist usage pattern like mine, how much Ketamine would they need to start with to achieve a sub-hole "sweet spot" dissociation? Of course this can't be a guaranteed tolerance conversion, but I'm curious to know how much a person with my exact tolerance to dissociatives should be recommended to start with in regard to Ketamine dosage.

 

[Asante]

Well, of course they are crosstolerant, so a MXE tolerance will translate directly to a Ketamine tolerance even if you havent used. I saw several people with experience with the genuine article claim that sublingual MXE is 1.5x as potent as snorted K, that people who get into a sublingual hole of 80mg MXE will do so equally but in shorter duration if they snort 120mg K.

Theres two levels of dissociative tolerance, reversible and irreversible. Most of your tolerance will revert if you wait a few months but if you used high doses often you may have built a permanent tolerance - which can mean both permanent desensiutization and permanent loss of magic - meaning NO dose will feel anymore like it did in the beginning.

 

[ElScorcho420]

if you used high doses often you may have built a permanent tolerance - which can mean both permanent desensiutization and permanent loss of magic - meaning NO dose will feel anymore like it did in the beginning.

I've never holed on any dissociative before, so my dosages have never exceeded maybe 80mg methoxetamine insufflated.

 

[Asante]

I recommend you to switch to sublingual, for MXE. In my experience the period that you Hole is equal to the period that the drug levels rise. For sublingual this lasts about 2.5 hours per increment. Snorted comes up faster so you pop out of the hole faster. If I get in the Holey Land I take 30mg sublingual bumps and these put me usually in the hole by minute 30-45, and back out again 2-3 hours after. Then, repeat until dead exhausted ^_^

 

[Survived Abortion]

Dissociative tolerance tends to last a long time - months or even years for some people depending on how heavy the usage was (dose and regularity). Someone who uses sporadically will only have to wait a few weeks for tolerance to return to noramls after a heavy night.

So I would expect some tolerance to linger from your MXE use. However, ketamine is a different drug with a slightly different pharmacological profile. If I were you I would begin with a normal dose, as if you were a dissociative virgin. You will easily be able to gauge the intensity of the effects from the first dose, and work out subsequent doses accordingly.

120-150mg sounds like a good dose to reach the fringes of the hole if you have little tolerance. If you are only looking for a "sub-hole sweet-spot" I would start with something around 60mg and work up from there.

Theres two levels of dissociative tolerance, reversible and irreversible. Most of your tolerance will revert if you wait a few months but if you used high doses often you may have built a permanent tolerance - which can mean both permanent desensiutization and permanent loss of magic - meaning NO dose will feel anymore like it did in the beginning.

No tolerance is ever permanent. That's physically impossible. It's just that dissociative tolerance can take a very long time to return to normal, meaning sometimes you may have to wait a couple of years to be able to get back to a good k-hole at the doses you were taking when you started. It may seem permanent, but of course that's just because you're comparing it to how long it takes for tolerance to psychedelics to return to normal.

 

[Asante]

These are neurotoxic drugs, you can actually damage the neural net irreversibly and that would give permanent tolerance. Think of users of MDMA who get complete loss of magic and find the magic is gone even after a decade of no use. Poke a neural net hard enough often enough and you change it.

 

[Survived Abortion]

^Show me some evidence.

The myths of MDMA neurotoxicity have been greatly exaggerated, and they don't even apply to dissociatives. As I've just recently pointed out in another thread, the human nervous system is very adaptive and resilient, and is constantly repairing and regrowing. If it wasn't, then we would have all succumbed to dementia and died straight after birth due to the constant assault of environmental toxins found in the air we breathe and the food we eat.

Of course you'll become a k-tard if you snort 5 grams a day for 3 years. That's nothing to do with the drug being inherently neurotoxic in itself, it's a case of unbalancing your system by overloading it with extreme amounts of the same molecule day in day out. The same would be true if you had chronic toxic levels of any of the essential minerals required for bodily health. If you ate a kilogram of spinach every day for 5 years you would also poison yourself.

 

[Survived Abortion]

^Show me some evidence.

The myths of MDMA neurotoxicity have been greatly exaggerated, and they don't even apply to dissociatives. As I've just recently pointed out in another thread, the human nervous system is very adaptive and resilient, and is constantly repairing and regrowing. If it wasn't, then we would have all succumbed to dementia and died straight after birth due to the constant assault of environmental toxins found in the air we breathe and the food we eat.

Of course you'll become a k-tard if you snort 5 grams a day for 3 years. That's nothing to do with the drug being inherently neurotoxic in itself, it's a case of unbalancing your system by overloading it with extreme amounts of the same molecule day in day out. The same would be true if you had chronic toxic levels of any of the essential minerals required for bodily health. If you ate a kilogram of spinach every day for 5 years you would also poison yourself, but it doesn't mean spinach is poisonous.

 

[slo mo]

Well, of course they are crosstolerant, so a MXE tolerance will translate directly to a Ketamine tolerance even if you havent used. I saw several people with experience with the genuine article claim that sublingual MXE is 1.5x as potent as snorted K, that people who get into a sublingual hole of 80mg MXE will do so equally but in shorter duration if they snort 120mg K.

Theres two levels of dissociative tolerance, reversible and irreversible. Most of your tolerance will revert if you wait a few months but if you used high doses often you may have built a permanent tolerance - which can mean both permanent desensiutization and permanent loss of magic - meaning NO dose will feel anymore like it did in the beginning.

I am grateful for such information. The last thing anyone wants is to lose the magic. So, how often can one do MXE, 3MeO PCP or K and not lose the magic?

 

[Asante]

I'm afraid it will turn out to be about the same as for psychedelics, to preserve the magic dose modestly once every 2 months or so.