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  • BDD Moderators: Keif’ Richards

Diminished Effects From Amphetamine Usages

D

d1430

Greenlighter
Joined
Jun 3, 2010
Messages
26
I used to get an intense speediness and dopamine high out of adderall. I had been using it in moderation to study until I abused it for school for a few days in a row taking around 100mg a day at most, and didn't take it for months after that. At another occasion I abused MDPV, binging and staying up for 3 days until I couldn't walk. Anyway now stimulants affect me entirely differently. I get very jittery and somewhat paranoid if I take adderall, ritalin, even five hour energy. It makes me feel shitty, jittery, sweaty palms, very worried and agitated until it passes. It feels really uncomfortable and I can't even converse with people. Perhaps it's good I cant enjoy stimulants anymore because I'm somewhat impulsive.

Just wondering if anyone has heard or seen this phenomena before. Why does this happen? How did my brain change to not being able to enjoy amphetamines or any stimulants at all?
 
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yeah i have this with ritalin. its more of a mind set. i would do like fourty mg of ritalin and get super paranoid. then other times i would be enjoying the high. its all in your head. take a month or so break than do it again with the right mind set. the best mind set for me was knowing i had more for some reason, probably he addict in me haha. i dont do that stuff anymore, especially ritalin, cuz i would always just get paranoid and jittery. but every few months, when your phycological tolerance has gone down, you can do it.
 
Interesting. I have been getting this way with mdma lately. Took a fair amount of m when I was at the Toronto Marijuana March this past weekend and I was mad paranoid the whole day. Everyone was just chilling smoking their bongs in the park and I was hiding from cameras and running from the voices in my head. What a fucked up day that was. Id like to believe that its just a state of mind thing, but this sort of thing has been happening to often recently for me to buy that.
 
This is a pretty basic effects question so I'll shoot it over to Basic Drug Discussion.



OD>>>BDD
 
Just wondering if anyone has heard or seen this phenomena before. Why does this happen? How did my brain change to not being able to enjoy amphetamines or any stimulants at all?
Click to expand...

This is called tolerance. The only way to get it back is to take a break from using amphetamines and let your brain and body repair itself. Amphetamine tolerance is one of the hardest ones to get back down to the level of getting euphoria from taking amphetamines.

I'm going to edit the title of your post for easier searching in the future.
 
I never had them as side effects before. Now they are the only effect. I took more than a semester off (around 5 months) basically with no stimulant use, tried adderall afterwards and I still get this.

Stimulants now make me sick. Mentally. I get a combination of miserable depressed and paranoid. Very very odd. Since my break I tried ephedrine, adderall, and caffeine tablets. Every stimulant has this effect on me. Actually last time I drank a five hour energy, I got really scare and miserable for about 40 minutes. Started getting very jittery and shaky, pale, palms sweaty, confused, the whole ordeal. It more or less passed after that 40 minutes, but the point is mild stimulants like 5hour energy and caffeine tablets make me feel like this. Sucks. I honestly get nothing good out of stimulants anymore.

It has nothing to do with mindset. It's literally impossible to relax when this happens and it's irrelevant how relaxed or happy you are before.

Don't know, just very weird having this happen. Would love for this to go away so I can use addy for finals next time around, but it won't
 
i think its mental. youve had bad experiences and now in the back of your head your afraid itll happen again so it does. at least this was my case with weed. had an anxiety attack once than after that kept almost having them because i was afraid it'd happen again. i eventually got back in a good mental state before i smoked. fortunately amphetamines still do good on me. i could be wrong about your situation though it could have just done something permanent to your brain maybe? and now you cant enjoy them. best to just not do them anymore but if you do really make sure your in a good fun setting and good mind set
 
Take magnesium, it lowers amp tolerance.
Make sure you get the non laxative kind though... Lol
 
It's important to understand how all amphetamines work on the brain. I don't want this to freak you out, but amphetamines are one of the few drugs that actually change brain chemistry in a pseudo permanent capacity.

First off, all stimulants have come downs. That goes for coke, adderall, dexedrine, ritalin, obviously mdma, and even caffeine. These come downs get worse after binges. Adderall is probably the smoothest of all typical amphetamines. That's because its a mixture of L and D amphetamine in 2 different salt forms each. So the rate at which it leaves your body isnt alarmingly quick. But building tolerance to it isnt like building tolerance to other drugs because its not purely receptor based. In other words...theres no amphetamine receptor that gets down regulated with too much use.

Amphetamines work by actually ENTERING your cell and signaling the cell nucleus to release DA, SERT, and NE. The stronger the amphetamine (pure D amphet like dexedrine, methamphete, or just high doses of addy) obviously increases the strength of that release. Then, the amphets also act as allosteric modulators on the transporter proteins outside the cell that are responsible for bringing extra DA, SERT, and NE back for recycling. They reverse this process and make the transporters forcibly remove all those extra neurotransmitters your nucleus pumped out. It effectively causes a 'shredding' of the synapse. In low-moderate doses, this effect is negligible. But a few really strong binges will twack your cells out. That's why you see meth addicts with parkinsons. Even after a meth addict gets clean...their dopaminergic transmission is so F'd up that they develop parkinsons symptoms.

So...I'd suggest avoiding the gnarly comedowns and crashes and lack of a good high but NOT trying to get high...at least for a few months. Also...the neurotransmitters that amphets release come from protein. So if youre not eating enough meats and cheeses...your cells won't have anything to release. And when they do...the synapses are so damaged and your metabolism (bi-product of tolerance) has gotten so good at washing out the amphets that DA, SERT, and NE release no longer happens on a nice, slow, smooth scale but just kinda stops. Then you crash. Let your brain heal for a bit.
 
Unfortunately with my experience with amps, is that even after several weeks without using it, it really does not feel the same.

The binging, while it is awesome, also sacrifices future effectiveness of the drug. I have binged off of amps before, and you will require a ton more next time, not to mention the stupid side effects never fade away, they are always just as shitty as before.

I have built up a tolerance with opiates in the past, then stopped for several months. When I came back to them, they felt like the first time I ever took opiates. My tolerance also fell way back down to day one. It is quite easy, you just take an opiate after a long break, and enjoy the buzz, and nothing is different about it.

With amps its like you have memory you will never forget. I have unfortunately had a couple "near OD" experiences with adderall. My heart was pounding, I took too much, had severe anxiety and fear of having a heart attack. When I got over it, I noticed that it totally fucks up your tolerance and it ruins the pleasant experiences next time. I've experienced this type of "super man" feeling with adderall. You think you can do so much more, so you do. With other drugs, once I feel good, I discontinue use for the time being.
 
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Adderall is probably the smoothest of all typical amphetamines.

really? when the word "smooth" comes to my mind, and alot of others that ive read, smooth means less speedy. which adderall is probably the most speedy because of the l-amphetamine
 
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