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  • BDD Moderators: Keif’ Richards

Dihydrocodeine recreationaly and poternators

P

pillboxskid

Bluelighter
Joined
Oct 21, 2012
Messages
111
Hi ya folkz for about 6 months now i,ve been using recreationaly dihydrocodeine at 300mgs.Also poternators 20 ml diazepam 20 zolpidem and 100 mgs diphydryamine. The last 2 months i.ve been using the same poternators at a dose of 410mgs feeling only a little. Would it hurt to go up to 530mgs and use the usual potenators?
All sujjestions welcome thankyou 8(


ps. do Gabapentin and Diazepam poternate each other? Thanks again!!!! :D
 
You won't be in trouble if that's what you want to know. But be very careful, you're facing here a double addiction, two particularly nasty ones.

Is your DHC OTC? And that's quite a big combo with all the benzos and non benzos added... Anyway, I urge you to go see a doctor for him to try to regulate with you your consumption. Two months of this regimen, you're already on a tight rope imo.
 
You mean "potentiators" I assume? Both diazepam and DPH are good potentiators of opiates, although I cut down the diphenhydramine dosage personally due to unwanted side effects. I'd leave the zolpidem out completely, I can't see it bringing much to the table in terms of recreation. Be careful with mixing the diazepam or the zolpidem with your DHC. It's a potentially dangerous cocktail.

Yes, gabapentin certainly potentiates diazepam or any other benzo.
 
You don't want to take diphenhydramine because it inhibits action of the enzyme 2D6. Dhc is a prodrug for dihydromorphine , or in other words, dhc must be metabolized into dihydrmorphine by the enzyme 2D6 for euphoria and pain killing effects . If 2D6 is inhibited, dhc will seem weaker than usual

Second there is a difference between synergy and potentiation . For example, Diazepam synergizes well with dhc because it doesnr increase the amount of dhc absorbed or metabolized, but rather it adds cns depression, muscle relaxation, and anxiolytic properties combine well with dhc pain killings effects and dopamine release in the cns. On the other hand, white grapefruit juice would be a potentiate dhc by indirectly increasing the amount of dihydrmorphine that can bind to mu opiate receptors . Eating a raw grapefruit contains the most amount of alkaloids that are moderately strong at inhibiting 3A4 which is the enzyme that converts dhc into inactive metabolites which will be flushed out of your body. By blocking 3A4 , dhc has s strong probability of being metabolized into dihydromorphine by 2D6 instead of inactive shit by 3A4

Gabapentin is an synergizes exceptionally well with opiates. I would definitely add some in, neurontin will increase analgesia from dhc, and it will make your diaZepam feel stronger. Good thing is that gabapentin causes minimal cns depression and almost extremely impossible to od on if you have a toleranc

I also recommend smokn weed, but only if you are a regular smoker. Marijuana creates the best synergy with opiates and almost every drug IMO


Make sure you exercise if your condition allows for light exercise. Exercise is the best natural painkiller; like 15 mins of walking around the block, or s bike ride, or tennis, ect..sometging not so intense but will still get your heart rate up
 
Last edited:
pillboxskid said:
Hi ya folkz for about 6 months now i,ve been using recreationaly dihydrocodeine at 300mgs.Also poternators 20 ml diazepam 20 zolpidem and 100 mgs diphydryamine. The last 2 months i.ve been using the same poternators at a dose of 410mgs feeling only a little. Would it hurt to go up to 530mgs and use the usual potenators?
All sujjestions welcome thankyou 8(
ps. do Gabapentin and Diazepam poternate each other? Thanks again!!!! :D
Click to expand...

How often do you recreationally use the Dihydrocodeine? I would,nt bother with the Zolpidem, the Diazepam will help potentiate somewhat but im not so sure about the Zolpidem.

Im more of an extremist and i dont recommend followingf what im doing, but i use anywhere between 600-1200mg Dihydrocodeine at a time.

As for the antihistamines i use as little as possible (just to get rid of the itch and possible nausea) Either 25 mg Diphenhydramine (but the post below warns against this) i also sometimes use 20-40mg Promethazine or very ocassionally Chlorphenamine.




laCster said:
You don't want to take diphenhydramine because it inhibits action of the enzyme 2D6. Dhc is a prodrug for dihydromorphine , or in other words, dhc must be metabolized into dihydrmorphine by the enzyme 2D6 for euphoria and pain killing effects . If 2D6 is inhibited, dhc will seem weaker than usual

Second there is a difference between synergy and potentiation . For example, Diazepam synergizes well with dhc because it doesnr increase the amount of dhc absorbed or metabolized, but rather it adds cns depression, muscle relaxation, and anxiolytic properties combine well with dhc pain killings effects and dopamine release in the cns. On the other hand, white grapefruit juice would be a potentiate dhc by indirectly increasing the amount of dihydrmorphine that can bind to mu opiate receptors . Eating a raw grapefruit contains the most amount of alkaloids that are moderately strong at inhibiting 3A4 which is the enzyme that converts dhc into inactive metabolites which will be flushed out of your body. By blocking 3A4 , dhc has s strong probability of being metabolized into dihydromorphine by 2D6 instead of inactive shit by 3A4

Gabapentin is an synergizes exceptionally well with opiates. I would definitely add some in, neurontin will increase analgesia from dhc, and it will make your diaZepam feel stronger. Good thing is that gabapentin causes minimal cns depression and almost extremely impossible to od on if you have a toleranc

I also recommend smokn weed, but only if you are a regular smoker. Marijuana creates the best synergy with opiates and almost every drug IMO


Make sure you exercise if your condition allows for light exercise. Exercise is the best natural painkiller; like 15 mins of walking around the block, or s bike ride, or tennis, ect..sometging not so intense but will still get your heart rate up
Click to expand...
What antihistamine do you recommend?
 
I use Dihydrocodeine recreationally as much as possible .I get 60 30 mgs a week so maybe 4 times a week!
 
Hey guys, I read the whole thread and this is my first reply on this thread. I am also a dihydrocodeine user & love the feeling it gives me. I get somewhat energized and motivated so usually I just pop (currently) 8x30mg and I'm about to go up to 9 of them..I've been trying to watch how many I pop at once because $ and obviously overdose. I don't know how common or easy it is to OD on dihydrocodeine. Can someone tell me?
Also I've been trying to find some good "potentiators" but I guess according to a couple posts up im actually looking for a "synergy" I think..something to make the feeling of the high stronger but using the same amount of dihydrocodeine to prevent going up in dosage and to make my stash last longer. I've used 25mg of Benadryl which has the diphenhydramine in it and I've drank white grape fruit juice. I guess I must be a noob at this because Pally Pete above said he pops 600-1200mg..I'm a baby I guess lol
Any ideas/advice that would help me get the synergy affect? I don't want to over do it either..that would blow.
 
I take DHC and normal codeine. I either use Diphendryamine or Promethazine to increase sedation and to reduce itching and nausea from the codeine.

If it were me, personally, I'd drop the zolpidem altogether and change the anti histamine to something other than Diphendryamine and see how you go.

I'm not sure if moving up to 530mg of DHC is good idea as there is a ceiling effect for codeine at 400mg I think? However, I'm not sure if this applies for DHC to.
 
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