APAP is water soluble, It's not some big secret. It's not nearly as soluble as opiates though so while some APAP gets into the solution a large portion is filtered out during a cold water extraction.
The tobacco thing is news to me. I don't smoke or consume tobacco very often luckily.
so this means its just as soluble as codeine and we might be giving ourselves real liver damage (well you guys giving YOURSELVES DAMAGE because i get the quality pure codeine 60 mg phosphate tabs jajajajaja) this is breaking and needs to be put out their IT IS THE VERY FOUNDATION FOR HARM REDUCTION GOD DAMNIT BECAUSE ONCE YOUR LIVER GOES PFFT