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Determining the weight/volume of your LSD?

A

adrefofadre

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I just picked up a vial of lysergic acid. It's diluted in water, so I have no idea how much I actually have. I'm going to be dropping it on blotter paper, and I want to make sure that the dosages are right. I like to know how much of a given chemical I'm ingesting, and I like the people with whom I share it to know as well. Is there any easy way of doing this?

Edit: how about verifying that it is in fact LSD in the first place and not some RC?
 
Let a few drops dry on a ceramic or glass surface, then use ehrlich's reagent and marquis reagent. The ehrlich will be positive if it has an indolic structure (5-MeO-AMT or LSD) and the marquis will turn yellowish turquoise/blue/green in the presence of a halogenated psychedelic amphetamine. The marquis will be orange-brown in the presence of 5-MeO-AMT (I think).

The only way to easily tell what it is quantitatively is to test what the minimum dose is for effect, an easy way is to put a drop on paper and then eat a quarter of the piece of the paper. If you get an effect, then there's probably 100mcg in a dose, because around 25mg is threshold. If not, wait about 5 days, then try 1/2 of the piece of paper, etc. until you find activity and estimate the dose from there.
 
Yeah...3 days is sometimes okay (Shulgin's duration between testing) but I use 5 to make sure.
 
Nuke's test is anecdotal test; nonetheless nuke is a smart bee;
that stated think hard about wha the said

at any rate do a paper chromatography test on the LSD to see if the lsd separates into the proper number of bands
 
Just put what should be a dose into a glass container with an airtight screwtop & sit it in fromt of a 500W halogen light for a day. All of the other imposters that commonly masquerade as LSD are pretty stable, whereas LSD is not, so a major/total loss of activity (due to heat & high levels of UV kicked out by halogen lamps) marks it as LSD...
 
Beenhead said:
Ive used paper chromatography before, but the average bear cant get chrom strips. I guess maybe from the internet
Click to expand...

It's cheaper and faster to just use field test reagents, and while paper or TLC would work I don't know exactly what the reference data would be for paper chromatography of LSD and related psychedelics.

Though ninhydrin may really be the simplest test to differentiate LSD from DOx or 5-MeO-AMT, as both the latter contain primary amines and will react while LSD only contains tertiary amines except for the indolic secondary amine which I don't believe reacts with it (but I might be wrong).

edit: Seems I'm correct,
Ninhydrin-acetate reagent reacted strongly only with Trp, but barely or not at all with indole compounds
Click to expand...
http://www.blackwell-synergy.com/doi/abs/10.1016/S0378-1097(03)00605-0

Thus DOx or 5-MeO-AMT should produce a purple reaction with ninhydrin

Not to mention ninhydrin is also pretty dirt cheap

Edit:
http://www.usdoj.gov/dea/programs/forensicsci/microgram/journal_v1/mjournal_v1_pg4.html

Ninhydrin reacts blue with LSD (not sure why?) but purple with primary or secondary amines on phenethylamines except for amphetamine which is brown, so I'd guess further testing is needed

This japanese paper notes the reaction of ninhydrin with 5-meo-amt but I'm not sure quite how to read it, it's sort of ambiguous:
http://www.tokyo-eiken.go.jp/issue/journal/2006/pdf/57-16.pdf
but it has the references for a lot of RCs

Engelhart, D. A.; Jenkins, A. J. J. Anal. Toxicol. 2002, 26 (7), 489-492 has refs for color reagents/spectra of 5-MeO-AMT but I don't have access
 
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