Znegative
Bluelight Crew
I cant really get if you guys are dissagreeing or not, but this is how I see it.
Buprenorphine is a partial agonist. That being said, it is an incredibly potent partial agonist, with opioid agonist effects equivalent to 30-50 mg of methadone.
Bupe blocks in a different way than methadone does. Methadone raises your tolerance to the point where your opiate receptors are so saturated with methadone, that other opiates just cant touch it. You can no longer experience euphoria, just increased resperatory depression.
Buprenorphine binds strongly to the opiate receptors, so that when you take a percocet, it acts as an antagonist. The bupe is so tightly lodged into that receptor (again, I'm sure this is very simplified), that the oxycodone has no where to connect, and it just swims around in your blood. However, after a certain ammount of time without buprenorphine in your system, it begins to fall off these receptor cites, and when enough fall off, you start to enter withdrawal, and full agonists will work again (though after repeated dosing of bupe, your receptors get a little muddied, so the high's are not quite as euphoric). You still will be left though with the tolerance from bupe, after say, 72 hours, because like I said, it is a very potent opioid, partial agonist as it may be.
Even after five days, I would think it would be almost impossible to get high off of a weak drug like codeine. (remember .3mg bupe is = 10 mg morphine I.V.)
In the end it is a combination of bupe's high affinity, as well as the fact that it raises your tolerance. If you taper though, you will have a lot easier time getting off for one, as well as getting high off of other opiates. I gaurantee that 36 hours off of 2mg you will get way higher on oxy than you would 72 hours after 16 mg.
Buprenorphine is a partial agonist. That being said, it is an incredibly potent partial agonist, with opioid agonist effects equivalent to 30-50 mg of methadone.
Bupe blocks in a different way than methadone does. Methadone raises your tolerance to the point where your opiate receptors are so saturated with methadone, that other opiates just cant touch it. You can no longer experience euphoria, just increased resperatory depression.
Buprenorphine binds strongly to the opiate receptors, so that when you take a percocet, it acts as an antagonist. The bupe is so tightly lodged into that receptor (again, I'm sure this is very simplified), that the oxycodone has no where to connect, and it just swims around in your blood. However, after a certain ammount of time without buprenorphine in your system, it begins to fall off these receptor cites, and when enough fall off, you start to enter withdrawal, and full agonists will work again (though after repeated dosing of bupe, your receptors get a little muddied, so the high's are not quite as euphoric). You still will be left though with the tolerance from bupe, after say, 72 hours, because like I said, it is a very potent opioid, partial agonist as it may be.
Even after five days, I would think it would be almost impossible to get high off of a weak drug like codeine. (remember .3mg bupe is = 10 mg morphine I.V.)
In the end it is a combination of bupe's high affinity, as well as the fact that it raises your tolerance. If you taper though, you will have a lot easier time getting off for one, as well as getting high off of other opiates. I gaurantee that 36 hours off of 2mg you will get way higher on oxy than you would 72 hours after 16 mg.
I think we're pretty much agreeing. 
but I am pretty sure there is some bomb dope in AZ. Not like you are better off going back to that (I know I wouldn't be). How long has it been since you last took any bupe/sub?