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Database of Designer Drugs

B

blowjay

Bluelighter
Joined
Jan 7, 2010
Messages
372
I somehow stumbled across this while trying to see if doxylamine succinate could maybe be converted to something recreational. This proved to be a very interesting find. GOBS AND GOBS of designer drug names and structures and mass spec to wash it down!

I am sure someone on here would find some of the stuff on the site worth purchasing. Seems to be a very very easy way to compile data related to structure, synthesis, and metabolites.

Here are some copy pastas
______________________________________________________________

10,450 chemical compounds
12,312 mass spectra, about 1,300 more spectra than the 2009 edition
Chemical structures

Compound Classes
Class Number

amphetamines 1030
methylenedioxyphenethylamines 533
phenethylamines 1340
tryptamines 317
piperazines 361
opiates 233
fentanyles 320
cathinones 267
phencyclidines 14
tropines 73
indoles 145
barbiturates 58
cannabinoids 84
cannabimimetics 57
steroids 63
arylpropan-2-amines 109
arylbutan-2-amines 394
1-aryl-2-nitro-ethenes 41
1-aryl-2-nitroprop-1-enes 65
1-aryl-2-nitrobut-1-ene 44
benzaldehydes 141
designer drug isomers 606
derivatives 3587
metabolites incl. derivatives 2596
chemical warfare agents 67
designer drug precursors 639
pharmaceutical drugs incl. metabolites 3357
pesticides 199
explosives 25
controlled compounds 1148

... and that is about all i feel like posting to gain interest.

It would be nice if someone would buy their stuff and format it so it can easily be shared, for the sake of research.

I would gladly seed it for eternity if it was put in a torrent.

Just thought I would be kind.
 
Added their other spreadsheet to the "free chemical databases" sticky
 
blowjay said:
http://www.sisweb.com/software/ms/wiley.htm

I found prices.

Its worth it.
Click to expand...

It really isn't worth several thousand Euro for a database that is out of date unless you are in to analysing RC samples from around the year 2000. Also all the compounds mass spectra are available elsewhere. There is practically no value in having spectra for homologous series.

the database is also packed out (some would say padded) with compounds that are in the NIST and other Wiley databases.

something that would really be worth the money are big pharmas internal databases, but they are never ever going to be public.
 
Bah, typical coming from Wiley, they are greedy corporate slugs, who care bugger all for the furtherance of scientific progress and the dissemination of information to those who can advance the state of the art knowledge.

Wiley are well known for a bunch of bloated moneygrubbing parasites.

You should see how much they want for a journal article. I would have no problem paying royalties to liscence a product or drug for commercial use if I were in business, that is fair, and it rewards the inventor, or at least, it should reward the deserving who put the effort and work in.

But paying through the nose to read the research? that is disgusting practise I think.

And worse, I have many times seen those pricks at Wiley give an 'abstract', which is intended to let one see at least a quick summary of the actual content and spirit of the article, their 'abstracts' are sometimes no more than the journal name, date, title and DOI identifier, they try and palm that off, then still expect people to eat dog shit and crap platinum.
 
Last edited:
vecktor said:
the OP has vision. reduction of doxylamine to the piperidine and then cleavage of the ether followed by esterification would give a interesting reverse ester related to ritalin.
Click to expand...

I know this gets close to synthesis discussion, but by my understanding of what this forum says, this type of post is allow.

I have been having some novel thoughts of seeing aspartame pop off everything facing offwards of the carbonyl groups and then transform the previous carbonyls to methyls.


aspartame.jpg


methamphetamine.gif


No idea if/how it could be done, but if aspartame was "cut" at the two carbonyls and methyl groups "grown back" instead in their place, that would make for some sweet results.

The terminology was a joke, but I am curious as to whether aspartame could yeild anything. Not just meth, just curious if a sugar substitute could be used to make something.
 
Aspartame to (meth)amphetamine is possible. Question A is: Is it feasible? Question B is: Can we really discuss this here?

Answer to B is clearly: NO! Answer to A I leave to you...


- Murphy
 
I was hoping for more of a clear answer towards this, but I would be very interested in figuring this out for myself. I need this kind of project. At least in writing, no way I would try carrying this out, a lot to go with purifying it and separating the unwanted from the wanted, all kinds of fun.

I am glad that you think it atleast possible. That is mainly what I am asking.

Does anyone else think this possible? That is the last question I will ask on the matter.

On a related note, does anyone have anything to contribute that is related to my original goal of having a large database? I mean something shareable, like a program of some sort just to compare chemicals. Offline programs preferably. I think we need to start getting some project like this together to share. I know I'm a noob here but this would be a great idea (unless its already been done).
 
methyl phacetoperane. Had wondered about about the doxylamine derivative, though as the pyridine, not the piperidine. Makes more sense though.

With the millions of threads devoted to stupid stimulants and the tens of millions devoted to acetyl loperamide, I'm amazed this hasn't been brought up even once before.
 
Well could we get some comparative pics of the molecules of methylphenidate, doxylamine and the proposed chem posted? I am too new at using this, can't embed the images right.
 
Oh and does methyl ethyl ketone to 2-methyl-2-butanol sound reasonable also? I have just been getting a little crazy lately with the ideas.
 
Oh and does anyone know anything about 3,4 dimethoxyphenethylamine? Is it active/why isn't it?
 
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