Dark chocolate consumption improves leukocyte adhesion factors and vascular function in overweight men
Diederik Esser,*,? Monica Mars,*,? Els Oosterink,*,? Angelique Stalmach,?
Michael M?ller,*,? and Lydia A. Afman*,?,1
ABSTRACT: Flavanol-enriched chocolate consumption increases endothelium-dependent vasodilation.
Most research so far has focused on flow-mediated dilation (FMD) only; the effects on other factors relevant to endothelial health, such as inflammation and leukocyte adhesion, have hardly been addressed. We investigated whether consumption of regular dark chocolate also affects other markers of endothelial health, and whether chocolate enrichment with flavanols has additional benefits.
This study provides new insights on how chocolate affects endothelial health by demonstrating that chocolate consumption, besides improving vascular function, also lowers the adherence capacity of leukocytes in the circulation. ?Esser, D., Mars, M., Oosterink, E., Stalmach, A., M?ller, M., Afman, L.A.
Dark chocolate consumption improves leukocyte adhesion factors and vascular function in overweight men. FASEB J. 28, 1464?1473 (2014). www.fasebj.org
https://sci-hub.tw/10.1096/fj.13-239384
Diederik Esser,*,? Monica Mars,*,? Els Oosterink,*,? Angelique Stalmach,?
Michael M?ller,*,? and Lydia A. Afman*,?,1
ABSTRACT: Flavanol-enriched chocolate consumption increases endothelium-dependent vasodilation.
Most research so far has focused on flow-mediated dilation (FMD) only; the effects on other factors relevant to endothelial health, such as inflammation and leukocyte adhesion, have hardly been addressed. We investigated whether consumption of regular dark chocolate also affects other markers of endothelial health, and whether chocolate enrichment with flavanols has additional benefits.
This study provides new insights on how chocolate affects endothelial health by demonstrating that chocolate consumption, besides improving vascular function, also lowers the adherence capacity of leukocytes in the circulation. ?Esser, D., Mars, M., Oosterink, E., Stalmach, A., M?ller, M., Afman, L.A.
Dark chocolate consumption improves leukocyte adhesion factors and vascular function in overweight men. FASEB J. 28, 1464?1473 (2014). www.fasebj.org
https://sci-hub.tw/10.1096/fj.13-239384
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