i-POOP-outside
Bluelighter
..........CWE-30-Tabs-8mg-codeine-300mg-Acetaminophen..........And 2-4 Promethazine-25mg to go with it......Good or Bad Idea? And...........is it close to that "Purple Drank" stuff from the south?
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BDD Moderators: Keif’ Richards | negrogesic
CWE & Promethazine...............
- Thread starter i-POOP-outside
- Start date
Psychedelic Jay
Bluelighter
It sounds just about right to me.
I would only take 2 of those promethazine pills though.
I would only take 2 of those promethazine pills though.
Psychedelic Jay
Bluelighter
It will add a little drowsiness and body load to the codeine.
Not much to the euphoria.
I'd rather you have a glass of wine.
People are concerned with liver problems with APAP and alcohol.
But here he is going to eliminate most of the APAP, and a couple of beers or a glass of wine is less than three alcoholic beverages. Plus the alcohol will help turn more of the codeine to morphine in your system. Then, I would leave the promethazine alone.
Not much to the euphoria.
I'd rather you have a glass of wine.
People are concerned with liver problems with APAP and alcohol.
But here he is going to eliminate most of the APAP, and a couple of beers or a glass of wine is less than three alcoholic beverages. Plus the alcohol will help turn more of the codeine to morphine in your system. Then, I would leave the promethazine alone.
Psychedelic Jay
Bluelighter
For the added painkilling, not so much for recreation.
It is for the nausea too, don't get me wrong.
It is for the nausea too, don't get me wrong.
Levvytation
Bluelighter
- Joined
- Feb 2, 2009
- Messages
- 439
What everyone in the above posts say is right. But no-one has pointed out that with codeine its VERY important to wait until the codeine has reached its peak before you take your promethazine.
Codeine is unique among opiates because it needs to be metabolised by the liver into morphine. Promethazine effects that metabolisation process, effectively lessening the effects of your codeine. Take your prometh after the codeine kicks in, then the promethazine/enzyme/liver metabolism thing works to your advantage, helping to keep all that lovely cvonverted morphine where it is, in your system.
Psychedelic Jay
Bluelighter
In most cases I would leave anti-histamines alone with codeine.
Codeine needs to be taken with an inducer to give it a real "boost", not just a "synergism".
I wouldn't sweat promethazine if it were missing, but to me 30 mins is too soon to take them.
I'd wait an hour.
Codeine needs to be taken with an inducer to give it a real "boost", not just a "synergism".
I wouldn't sweat promethazine if it were missing, but to me 30 mins is too soon to take them.
I'd wait an hour.
Psychedelic Jay
Bluelighter
What? It is so my friend.
Psychedelic Jay
Bluelighter
Thank you. Captain Obvious.
drug_mentor
Bluelight Crew
In my experience 50mg of promethazine taken a bit over an hour after drinking CWE adds a little sedation, reduces itching and reduces nausea.
I find doxylamine succinate is a good antihistamine because I can take it before the codeine and it works fine. One I took 50mg of diphenhydramine on the peak of a codeine high and it killed the high 15 minutes later.
I find 60mg of DXM 45 minutes to an hour before dosing with codeine is helpful to increase the high, as is having a few units of alcohol (2-3).
I find doxylamine succinate is a good antihistamine because I can take it before the codeine and it works fine. One I took 50mg of diphenhydramine on the peak of a codeine high and it killed the high 15 minutes later.
I find 60mg of DXM 45 minutes to an hour before dosing with codeine is helpful to increase the high, as is having a few units of alcohol (2-3).
Psychedelic Jay
Bluelighter
DXM is an inhibitor, and taking it with codeine is blocking some of codeine's conversion to it's active metabolites.
DXM causes it's own euphoria in it's own right, which is why you felt great.
If you take the DXM with an opiate that is already orally active without conversion, you will see a big difference.
Anti-histamines only stop nausea, and add numbness and drowsiness to the opiate, not euphoria.
And no anti-histamines should be added before or too early after the codeine, or you could reduce the amount converted in your liver.
Alcohol and other inducers greatly add to the sedation and numbness of the opiate, but it boost the amount converted, rather than inhibit it. When it comes to opiates with more powerful metabolites, using inducers GREATLY add to the euphoria. And there are better inducers out there than just alcohol alone.
Soma, and other drugs that induce similar actions to barbiturates, increase this conversion so much, that codeine can feel like hydrocodone and other more powerful drugs that act on the same receptors.
Many have concerns on duration after inducers are added. This is of no real concern, because there is so little difference.
DXM causes it's own euphoria in it's own right, which is why you felt great.
If you take the DXM with an opiate that is already orally active without conversion, you will see a big difference.
Anti-histamines only stop nausea, and add numbness and drowsiness to the opiate, not euphoria.
And no anti-histamines should be added before or too early after the codeine, or you could reduce the amount converted in your liver.
Alcohol and other inducers greatly add to the sedation and numbness of the opiate, but it boost the amount converted, rather than inhibit it. When it comes to opiates with more powerful metabolites, using inducers GREATLY add to the euphoria. And there are better inducers out there than just alcohol alone.
Soma, and other drugs that induce similar actions to barbiturates, increase this conversion so much, that codeine can feel like hydrocodone and other more powerful drugs that act on the same receptors.
Many have concerns on duration after inducers are added. This is of no real concern, because there is so little difference.
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