Stereo, I think it was useful -- we got a lot of good, real-life replies on how meth negatively impacted people's lives. The OP was correct in that a lot of E users assume that meth is a "bad drug", but I think this thread had challenged and reaffirmed that assumption. Pharmacologically speaking, I think the two are comparable. Meth and MDMA are both amphetamine analogues, and they both reverse the action of reuptake inhibitors. Meth just happens to be strongly dopaminergic and brutally effective, which apparently makes all the difference in terms of its addiction profile.
Personally, I don't believe that there is such thing as a "bad drug"; even a drug like methamphetamine has something to offer. Any disturbance from one's natural state helps to more clearly define the boundaries of that state and meth, like any other psychoactive drug, definitely does disturb the natural state.
As always, there's a risk/benefit ratio, and meth is *strongly* skewed in risk direction. In the spirit of harm minimization, I agree, people should avoid meth; it's simply not worth the risk. Nevertheless, one must admit that it's just a drug -- it's not good or evil in and of itself, and has use both medicinally and for (albeit limited) self-exploration.