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Could you get more out of weed if you breathe out you nose.

D

denotsneo

Greenlighter
Joined
Apr 29, 2009
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4
I was just sitting thinking about this does anyone have any idea if it would make any difference. My thinking was that as the blood vessles in the nose are very sensitive would they absorb some of the THC.
Apreciate anyone who might have a idea about it.
 
Well, the cannabinoids aren't very water soluble, so they aren't absorbed intranasally well if at all. It may make no difference at all.

I've been blowing my hits out of my nose for years, just in case. I also hold my hits in until my lungs are going to burst, every time.
 
there is no need for that.

i remember once my friend flipped the blunt over and put the lit side in his mouth to blow the smoke outwards. i then snorted the smoke and it gave me a pretty big head rush, but nothing noticeably different
 
what's nasty about taking a shotgun to the dome(through the nose)?

:) shotguns = win

and for the OP: As for your nasal cavities actually absorbing a significant amount of cannabinoids, if any, to have an effect, that's just wishful thinking.
 
http://www.sciencedirect.com/science?_ob=ArticleURL

Intranasal absorption of Δ9-tetrahydrocannabinol and WIN55,212-2 mesylate in rats

The aim of this study was to examine the potential of the nasal route for systemic delivery of Δ9-tetrahydrocannabinol (Δ9-THC) and WIN55,212-2 mesylate. Anesthetized rats were surgically prepared to isolate the nasal cavity, into which Δ9-THC (10 mg/kg) or WIN55,212-2 (150 μg/kg) in propylene glycol alone or propylene glycol and ethanol (9:1) were administered. Rats were also administered Δ9-THC (1 mg/kg) and WIN55,212-2 (150 μg/kg) intravenously in order to determine absolute bioavailabilities of the nasal doses. Plasma Δ9-THC and WIN55,212-2 concentrations were determined by liquid chromatography/mass spectroscopy (LC/MS). The pharmacokinetics of the drugs after intranasal administration was best described by a one-compartment model with an absorption phase. WIN55,212-2 was absorbed more rapidly (Tmax = 0.2–0.3 h) than Δ9-THC (Tmax = 1.5–1.6 h) and to a higher extent than Δ9-THC.

Addition of ethanol (10%) to the formulations had no significant effect on the Cmax after nasal administration (p > 0.05). Furthermore, it had no significant effect on the absolute bioavailability (Fabs): Fabs = 6.4 ± 2.4% and 9.1 ± 3.0% for Δ9-THC in propylene glycol, with and without ethanol, respectively. For WIN55,212-2, Fabs = 49.9 ± 6.9% (propylene glycol alone) and 56.6 ± 14.1% (propylene glycol with 10% ethanol).

The results of the study showed that systemic delivery of Δ9-tetrahydrocannabinol and WIN55,212-2 could be achieved following nasal administration in rats.
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http://www.ukcia.org/research/pipes.htm

Marijuana Water Pipe and Vaporizer Study
 
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ok so without all those MDHSFUSFNEFE things in that paragraph are you basically saying it is effective and if it is, it's more effective??
 
After I got my wisdom teeth out, I could only take hits through a bowl THROUGH MY NOSE!!

Shit!!!!! Burned like a mofo, was probably a dumb thing to do, but it killed the pain and I only did it for 2 days. I feel as if I got more high from smaller hits.

As a side note, I almost always french inhale my hits, and it makes a noticeable difference.
 
chainer3k said:
After I got my wisdom teeth out, I could only take hits through a bowl THROUGH MY NOSE!!

Shit!!!!! Burned like a mofo, was probably a dumb thing to do, but it killed the pain and I only did it for 2 days. I feel as if I got more high from smaller hits.

As a side note, I almost always french inhale my hits, and it makes a noticeable difference.
Click to expand...

8o
I HIGHLY do not recommend this. The oropharynx (your mouth and nose) is one connected airspace, except momentarily when you swallow. If you close your mouth and suck through your nose, the pressure in your mouth drops too. If you get dental work done, no sucking or forced inhalation means just that.

OP, the active chemicals in marijuana are absorbed in your lungs, so inhaling though your nose doesn't change absorption. It may reduce the amount of chemicals that REACH your lungs though, because the interior of your nose is convoluted and covered with hair, mucus, and skin folds, whose entire purpose is to keep things besides air from ever reaching your lungs.
 
Swift Serenity said:
ok so without all those MDHSFUSFNEFE things in that paragraph are you basically saying it is effective and if it is, it's more effective??
Click to expand...
LOL!

There is absorbtion but not as effectively as through your mouth, and the high diminishes much quicker, so why waste it? Plus it can be harmfull, as posted above by someone else!
 
I think the most effective way to inhale is to take the biggest hit you can take without choking it out, then let a bit out, hold it, let a bit out, hold it etc till its gone. When you let some smoke out then hold it it causes little microscopic tears in the lining of your lungs and more thc gets in..

Using this method with a volcano I'd expect 99% bioavailability.. lol :0
 
Hyperventilating hash is a sure-fire way to get the thc straight to your brain. drop it on top of a coal, and suck it up with a straw, in through mouth, out through nose repeatedly until the hash is gone.
 
GlassAss420 said:
I think the most effective way to inhale is to take the biggest hit you can take without choking it out, then let a bit out, hold it, let a bit out, hold it etc till its gone. When you let some smoke out then hold it it causes little microscopic tears in the lining of your lungs and more thc gets in..

Using this method with a volcano I'd expect 99% bioavailability.. lol :0
Click to expand...
wow....thats almost as stupid as the people who think that putting glass in E pills cuts the stomach and helps the MDMA get absorbed.
 
Yeah I don't think it would make much of a difference if you breathed thru your nose. Your lungs are a pretty reliable transporter of THC to the brain considering it has thousands of nerve endings connected to the walls of the lungs. Idk, this just sounds like your desperate for a little bit higher rush or something. Just enjoy what you get out of a normal lung beating. haha.
 
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