It bears repeating - no drinking for a WHILE after consuming 150 mg butalbital. That dose will leave significant levels of that barbiturate active, in the blood, for quite some time, even if you do not "feel" it. To be cautious, I would wait even more than 24 hours before drinking after consuming the butalbital. It feels much stronger when it comes on - the feeling of the barbiturate drops much more quickly than the active CNS depressant effects of the barbiturate, again even if you do not feel it. Seriously, not a single drink. Barbiturates are incredibly dangerous drugs, on the whole, and drinking is not that safe by itself, either. The combination could EASILY result in death - like scary easily.