Complexing 25C-NBOME Hcl (HPBCD + Distilled Water)

[quantumtryptamine]

Dear Bluelighters!

This is my first post in here, i've been reading the website for a long time due to my good relationship with psychedelic chemistry (I've made several extractions from plants and try them out! ) but never registered in, now i'm here to ask you something and see if i'm making the correct...

I've owned from a good vendor a 100mg sample of the famous and wellknown 25C-NBOME HCL. My idea it's try to complex it with some HPBCD that i've got recently, then put this in distilled water and drop it into a 200 1X1CM blotter (so 1 1x1CM square would be around 500ug 25C).

The question is, i've read that the scale it's 1:9 (25C-HPBCD), should i mix the 100mg of the 25C with 900mg of HPBCD and then drop the mix into distilled water (I've read that the best option it's to put 8mg 25C/1ml of distilled water, following this, i must use 12,5ml of distilled water for this test). Or should i go in a different way?

My idea as i told before it's to first make the 25C-HPBCD mix, then drop the 12,5ml distilled water into a jar where the 25C-HPBCD is, mix the solution until everything seems to be disolved and then using a insulin syringe i would drop +/-0.0625ml of solution in every 1x1CM blotter, wait until it's dry and then try it out.

I've also read that ethanol it's a great solvent for this chems because it evaporates really fast, any idea of 25C solubility in ethanol to make this?

Anooooooother tek i've read it's to get a plate where the blotter fit exactly and then pour the 25C-HPBCD-DISTILLED WATER soultion into it and wait until it got dry.

Opinions? Is HPBCD needed to make HCL more efective in blotters? Also, i've read in several posts that freebased 25x-NBOMES are not soluble in water, but HCL it's, and if you have a freebase you should use HPBCD to complex it and make it more soluble and able to be absorbed sublingually, is this the same for the HCL?

I'm so in doubt with this, help would be so useful!

NOTE: IM NOT TRYING TO SELL THIS AS ACID, I'M JUST TRYING TO DOSE IT IN BLOTTERS BECAUSE I DON'T LIKE THE NASAL ADMINISTRATION.

Thanks.

 

[Solipsis]

Hello and welcome to Bluelight / PD, as an active participant.

Please read this:
http://www.bluelight.ru/vb/threads/604282-NBOMe-Subthread-Complexing

It should allow you to adjust your own calculations since I seem to recall a number of your questions being answered in that thread.

Also, check the Beginner's FAQ to get a better understanding of how to use the forum and find what you are looking for. We do encourage discussion in general, but obviously it is a shame if there is a thread effectively covering a topic while in a whole new thread someone is asking about it.

But I do understand you have some extended questions about this technique.

25C-NBOMe in HCl form should dissolve in water, but a number of people have reported difficulties with this. It can take some time and stirring apparently.
HPBCD is very soluble in water (should be over 500 mg/ml as a possible concentration)

If you mix the powders before adding to water, nothing will happen. There is no interaction and it will be the same as adding them to the water separately. In other words: it doesn't matter.

[Please don't say 25C-HPBCD, it will confuse people into thinking that you are talking about another compound]

Putting drops of solution onto blotter paper is a controversial, or just plain bad way to lay blotter unless you are using an excess of paper. If you are using small squares it is likely to oversoak / oversaturate the paper and it will spill. If you drop solution onto a larger sheet, the doses can easily bleed out to other hits and the result will just be terribly uneven.

I don't think you can measure 62 microliters with an insulin syringe like you suggest. There are microliter pipettes on the market that can do this but they cost some precious moneys. 62 microliters is near the volume of how a drop will form naturally, but there would be too much variance to actually just use drops to measure hits.

The proper way is to measure the absorbancy of the paper by first using the same solvent (distilled water, alcohol or a mix of the two) that you will be using for the actual drug, to check exactly how much liquid the paper is able to absorb without dripping or coasting puddles.
This can be checked by weighing the paper dry and completely wet. But it can be easy to mess up because of an excess of water or incomplete saturation. Because that can be easy to miss.

If you know how much liquid 'fits', you can calculate new concentrations and you then make that specific volume in that specific concentration. You allow that solution to be soaked up evenly and there should be no spills or dry zones. Let dry and you're done.


Freebase NBOMe compounds don't dissolve in water at all, but the HCl salts do in moderation. The water solubility corresponds (to some extent) to how well it can be taken up via saliva into the body. HPBCD is thought to facilitate absorption of something like the freebase which would be tough to put into solution in the first place, but beyond that point should be carried by the HPBCD. The same may be true for the HCl but I don't think we actually know by what ratio it improves effectiveness.