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Mental Health Coming off Invega/Xeplion (paliperidone) injections v 8.0

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bowandsparrow said:
I can officially feel joy again, so I'm going to consider myself recovered from here. I'll share more details when I'm back from my trip.
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Notice - you being able to trip isn't full recovery. You could compare your trip with how it was before, which is more accurate than just realizing you can trip again.
 
paliperidonevictim2005 said:
this shit is fucked man im only 18 years old my life has been hell since 10 or 11 my ex girlfriend set me up to be robbed at gunpoint by 4 guys i trusted that evil bitch and she did that this led me to have a big mental breakdown 2 days later they took my weed so i couldnt calm myself down with that and all my money phone etc and it led me to go to the mental hospital where they misdiagnosed a severely depressed kid with schizo and forced this evil poison on him at 18 i hope i recover but when i see people say they didn't recover it just makes me so fucking hopeless😔 i have some improvements but its not as much as i wanted
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Can you tell what improvements are you talking about ? I wonder if I have the same ones
 
dontGiveUp said:
Hello folks. Used to read these forums when I was suffering from these meds but I've got my head back now and feel much better.

Don't give up, it definitely gets better for most people (I really hope that's true, I've seen a lot of people recover).

The year it took me to Recover was hell, I felt awful but I just persevered and eventually my head began to fix itself. Sleep is better, dreams are back. For those that are interested 420 works (a little too much sometimes ;)), nicotine and drinking affect me as you'd expect.

There are some issues that remain but all in all I'm feeling good now.
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Hi, thank you for the support, I was wondering when you recovered your emotions and feelings, did it come back very slowly with ups and downs or did it happen rather quickly ?
 
All2027 said:
Hi, thank you for the support, I was wondering when you recovered your emotions and feelings, did it come back very slowly with ups and downs or did it happen rather quickly ?
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It was gradual for me. There's a lot of time with no improvement but after about 12 months I seem to have recovered over the proceeding 5-6 months where the mental abilities came back. I first realised it when I was laughing at old TV shows again. Also coffee, cigarettes (yes I'm unhealthy in that regard) and other things started to work well again. Some of it even seems stronger than it used to.

The science is confusing but I think the receptors cycled or the brain begins to adapt. All receptors recycle after 7 years maximum anyway but it's a continual process. Anyone who has been suffering for long term will get function back after 7 years anyway but for most of us 95%, from what I can tell reading this forum, we bounce back sooner.

t_xeplionhell said:
Notice - you being able to trip isn't full recovery. You could compare your trip with how it was before, which is more accurate than just realizing you can trip again.
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I trip hard on shrooms again and 420. In my case these things feel as powerful as when I first took them years and years ago. 420 is less of a 'trip' I know but the effect is hardcore - I spend hours looking at NASA space photography (those huge starfield photographs from telescopes) xD.
 
dontGiveUp said:
The science is confusing but I think the receptors cycled or the brain begins to adapt. All receptors recycle after 7 years maximum anyway but it's a continual process. Anyone who has been suffering for long term will get function back after 7 years anyway but for most of us 95%, from what I can tell reading this forum, we bounce back sooner.
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Brain cells are not recycled as you age apart for certain cells in the hippocampus (the area of the brain responsible for memory) which are replaced at a rate of about 1.75% per annum. So neurogenesis does occur, but not throughout the brain and certainly at nowhere near the rate of other cells of the body.

What the brain is able to do is to make up for deficits via neuroplasticity.
 
Woke up missing the way i was before and thinking of suicide. Life is not fun like this, i just want to leave the world behind. These drugs are murder. I don't think i'll heal.
 
Doea anyone even believe in the science of these drugs saying that they block dopamine and shit? If they merely blocked dopamine we were supposed to feel better as soon as we stopped taking them. I think what these drugs do is just a chemical lobotomy. It doesn't show up on a CT scan or a MRI but so does Chronic Traumatic Encephalopaty and it doean't make it less real. The question here is why the government think it's okay to lobotomize people.
 
lurker689 said:
Doea anyone even believe in the science of these drugs saying that they block dopamine and shit? If they merely blocked dopamine we were supposed to feel better as soon as we stopped taking them. I think what these drugs do is just a chemical lobotomy. It doesn't show up on a CT scan or a MRI but so does Chronic Traumatic Encephalopaty and it doean't make it less real. The question here is why the government think it's okay to lobotomize people.
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Well, chlorpromazine's nickname is 'the liquid cosh' and in the UK at least, psychiatric nurses refer to the the combination of 5mg haloperidol + 2mg lorazapam (for psychiatric emergencies) as a 'B52'.

The thing is, neuroleptics are dirty - they bind to dozens of receptor subtypes. The reason is that it's VERY hard to produce animal models of mental illness and unethical to develop new drugs using people as models.
 
AlsoTapered said:
Well, chlorpromazine's nickname is 'the liquid cosh' and in the UK at least, psychiatric nurses refer to the the combination of 5mg haloperidol + 2mg lorazapam (for psychiatric emergencies) as a 'B52'.

The thing is, neuroleptics are dirty - they bind to dozens of receptor subtypes. The reason is that it's VERY hard to produce animal models of mental illness and unethical to develop new drugs using people as models.
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It's also unethical to give such dangerous and lobotomizing drugs to "prescribed" people, which throw people into suffering and agony up to the point of where they'll beg for death, worse than heroin withdrawal and lasts much much longer even after quitting it.
 
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AlsoTapered said:
Well, chlorpromazine's nickname is 'the liquid cosh' and in the UK at least, psychiatric nurses refer to the the combination of 5mg haloperidol + 2mg lorazapam (for psychiatric emergencies) as a 'B52'.

The thing is, neuroleptics are dirty - they bind to dozens of receptor subtypes. The reason is that it's VERY hard to produce animal models of mental illness and unethical to develop new drugs using people as models.
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Injectables also stay long in the organism and the doses are overkill - Invega Sustenna for example.

Receptor tearing/wear-up by such drugs is also a serious issue which postpones recovery. There is also irreversible antagonism on few receptor types which means body must replace the whole receptor once invega binds to it, for the receptor to work again.
 
paliperidonevictim2005 said:
parkinsons is gone, i can laugh and smile sometimes, dont feel like zombie anymore
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How long did it take for the tremor or parkinson's to go away. This symptom is really starting to bother me. Plus i have been using nicotine as a way to gauge recovery. I could feel it 100% a few days ago but now it is back to being diminished. Being that it has been 122 days since I got the shot I just think this is proof of how the half life works. It's almost 4 30 days cycle on the money for it going through the system again and then continues to get less and less as the month goes. I'm almost positive i will heal but one a fucking mission this is, by far the most difficult thing I have ever been through. This shit fucks with your mind if you don't track progress. This is why people people see progress around month 4-8 because it is all getting out of your system. This truly is a year of recovery from one shot. Unbelievable!
 
Do you guys feel disconnected from people a little. Like you are there but since there are no emotions you don’t feel the presence internally. Also does music feel off cuz I don’t think it is hitting the same
 
AlsoTapered said:
Brain cells are not recycled as you age apart for certain cells in the hippocampus (the area of the brain responsible for memory) which are replaced at a rate of about 1.75% per annum. So neurogenesis does occur, but not throughout the brain and certainly at nowhere near the rate of other cells of the body.

What the brain is able to do is to make up for deficits via neuroplasticity.
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Did you have invega and recover?
 
Robchanna said:
Do you guys feel disconnected from people a little. Like you are there but since there are no emotions you don’t feel the presence internally. Also does music feel off cuz I don’t think it is hitting the same
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Yes and yes. Been with a girl for 24 hours I feel wack asf man I used to chill with this same girl when I was normal makes me really sad deep down.
 
AlsoTapered said:
Brain cells are not recycled as you age apart for certain cells in the hippocampus (the area of the brain responsible for memory) which are replaced at a rate of about 1.75% per annum. So neurogenesis does occur, but not throughout the brain and certainly at nowhere near the rate of other cells of the body.

What the brain is able to do is to make up for deficits via neuroplasticity.
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I think the receptors are cycled back into the brain cells and new ones emerge. I did talk to some biochemistry friends who work on this stuff and they have the same belief but it's a largely unexplored system, research is ongoing though. I'm a mechanical engineer so the most I use is calcium triggering systems you find in brains, the rest is not my field.
 
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