Hey everyone!
So, I decided to post for the first time in this thread. I've been lurking around and trying to find answers for my questions for a while now.
I had a drug-induced psychosis last November and I was hospitalized because of that.
First I was treated with risperidone which helped me get back to reality.
And like everyone, I was also poisoned with Xeplion a.k.a Invega. The first shot was just after New Years Eve this year (150 mg) and the second one (100 mg) was 2 weeks after the first one. Then I discontinued.
I first thought I was just so anxious and depressed back in the hospital that I got the negative side effects because of it and that they would just disappear after I'd been released,
but when I got home, none of the symptoms disappeared and this really made me panic.
Some of them just became even worse after getting home from the hospital.
It happened to somehow cure my HPV, I'm still confused about that. (at least the visible symptoms)
But anyways, since the day I got home from the hospital, I tried to look for a "cure" like almost everybody in this thread has tried to.
As for the negative symptoms I have/had were;
- terrible akathisia, I literally couldn't stay still for longer than 5 seconds, when I stood up, I had to walk around or move my legs or I'd feel horrible. (Akineton/biperiden diminished most of the akathisia after few weeks of usage)
- brain fog
- derealization
- no motivation to do anything
- no emotions, almost felt like a robot
- problems staying asleep, especially in the morning, I just wake up at the same time every morning, no matter what time I go to sleep
- anxiety / depression
- dark and suicidal thoughts which really made me scared
- muscle spasms all over my body
- difficulty concentrating
- erectile dysfunction and low libido due to high prolactin and probably low testosterone
- weight gain
- parts of songs getting stuck in the head
- pain on the right side of my head
- vivid nightmares
Now a bit over a month since my last shot I've started to feel a lot better. The first day I noticed a difference was exactly 1 month after the last shot.
The first thing I noticed was that by the end of the day I noticed I had no negative or suicidal thoughts for one day which felt amazing.
And after that day I've been noticing that everyday I just feel better and better. And I'm pretty sure it's because of the supplements I've been using.
My anhedonia has diminished a little during this week and my thoughts aren't racing that much anymore. I even tried to smoke some MJ but that didn't help at all.
I read this article about supplements which was really good;
https://www.optimallivingdynamics.c...diazepines-induced-guide-vitamins-medications
The supplements I've been using are;
5-HTP - 200 mg in the morning - 100 mg in the evening (precursor for serotonin, this made my anxiety/depression disappear on the first day I took it - I really recommend trying it but make sure you're not on antidepressants or on any other serotonergic drug since they interact with each other and it might result in a serotonin syndrome)
L-Tyrosine - 500 mg (precursor for dopamine, bought today, been feeling motivated enough to write to the forums, but can't tell for sure yet if it's doing anything or not)
L-Arginine - 500 mg (bought this one today too, can't comment on this one yet either)
Soy lecithin powder - 1 tablespoon (good source of choline / inositol, I take this for akathisia, seems to work)
Triple Magnesium - 270 mg (Invega depletes this)
Triple Zinc - 30 mg
CoQ10 - 200 mg (Invega depletes this too)
Liquid Iodine (helps to detox fluoride from brain, also helps with thyroid function)
Selenium - 100 mcg (should be taken together with iodine)
C vitamin - 500 mg (Invega depletes C vitamin)
B-Complex 50 (Invega depletes B vitamins)
P-5-P 100 mg (active form of vitamin B6, effective for lowering prolactin, also has some dopaminergic functions)
Boron - 3 mg (this should clear out the poison faster)
Glutathione - 50 mg (an antioxidant which prevents damage to important cellular components)
Omega Duo - EPA 900 mg / DHA 400 mg (this is just good for brain in general)
Vitamin E - 150 mg (this lowers prolactin)
Mucuna pruriens - 400 mg (this contains 15% L-DOPA which is a precursor for dopamine, also seems to lower prolactin)
Ginkgo biloba - 60 mg (this should lower prolactin)
Ashwagandha powder - 1 tablespoon (lowers prolactin, also a good source for iron)
I take all of these once I wake up in the morning, except for L-Tyrosine which I'm taking 2 hours after supplementing with 5-HTP.
They have some kind of supplement-supplement interactions and I read a recommendation that they should be taken at least 2 hours apart.
The supplement I recommend the most is definately 5-HTP. I'm no longer feeling suicidal/depressed/anxious which I still was like a week ago. This really made a difference in how I feel.
After I started using 5-HTP I feel like I got some of my cognitive abilities back and now I'm able to hold conversations and watch TV shows and actually laugh at them.
I also drink valerian tea and take 6 mg melatonin in the evening for sleep.
Valerian works on GABA so it relaxes you almost the same way as benzos do but in a natural way.
I've also been drinking a detox tea containing hibiscus, nettle and liquorice root.
This kind of stack of supplements may be hard for your liver or kidneys to process so take it easy with them. I just risk it for the biscuit.
Also drinking plenty of water is recommended for kidney health because most of the poison is excreted in urine by your kidneys apparently.
The circadian rhythm is messed up due the irreversible antagonism at 5HT7 receptors, which are involved in thermoregulation, circadian rhythm, learning/memory, and sleep.
But I managed to find an interesting article about clozapine and some other competitive antagonists which are able to reactivate the receptors which are deactived by risperidone/paliperidone.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052287/
I'm thinking of trying clozapine in an effort to reverse this antagonism, I'd really like to sleep well again.
I need to do a bit more research on this about dosing it etc. though before I'm trying it.
I'd also like to thank everyone who posted useful tips on these threads because without them I might be dead right now.
And I also want to tell everyone who has been poisoned by this awful drug that there is HOPE FOR EVERYONE.
You're not alone with the condition. I've made a lot of progress after just the first month by doing a lot of research so I'm pretty positive that it's possible to recover if not fully, then at least pretty darn close.
Brain is a very complex organ and the receptors etc. are recycling and you can speed up the process with the right tools.
Just eat healthy, have a positive attitude towards life, use the right supplements, go outside for a walk / exercise, spend time with your family and friends and take a day at a time.
What I do when I get anxious is that I think about the worst days I've had on this drug and compare those days with the day I had today.
Everyday is a progress. And research is the key.
I wish you all the best!
- Phuc
(I'm sorry for my English, it's not my native language so..)
I'll leave some useful links here;
https://www.reddit.com/r/steroids/wiki/the_estrogen_handbook/prolactin_supplements