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Mental Health Coming Off Invega Sustenna (Paliperidone) v.2

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I stopped takiing it a little under a month ago. I would like to connect to some friends on here and possibly chat on the phone so I can speak to someone who can relate to me. I experienced a temporary psychosis last year and was able to get back in line without any meds. I got into an argument with my case manager while I was in the hospital and then they would not release me unless I agreed to take this injection of invega. My vision is blurry, I have no sex drive, I have gained a lot of weight and my blood sugar is around 300 now. I am not motivated to get a job, I am living in a boxing gym on an old couch and I used to be well off. I dont have any self esteem to pick myself up and I noticed my face is changing. I am not getting paid and I am working just to have this place in the gym to live. I was in a relationship for 2.5 years and he left me so I feel alone all the time. I really need someone to talk to. People I know just say for me to get a job but I lost everything in my storage shed, including all my clothes so I have nothing for a job interview. This medicine has messed up my memory and I dont seem to comprehend instructions well like I used to. I feel like such a loser and I think about killing myself all the time since I started taking this medicine. I hate my life so badly! My number is 602 832 1422 if anyone feels like talking
 
Hi guys, I thought I'll post something really quickly (It actually took me 45 minutes to write this lol...). It is necessary for us to review the Bill of Rights. I was doing that just now for history. Here is a link to it, perhaps you can find a better one. https://www.billofrightsinstitute.org/founding-documents/bill-of-rights/

I was looking over it and I noticed that the Bill of Rights doesn't protect the rights of people with "mental illnesses". People with mental illnesses are not protected by Amendment VI(A6) against "criminal prosecutions" or against incarceration. Being held by gov't law against your will inside any facility makes that a prison. Going in front of a judge is a prosecution. You will clearly notice that the MH system bypasses the laws. In fact, even the laws that were made to protect people with mental illnesses did not exist until a case was bought up in State Courts. Other "rules" that doctors, nurses, rest of the staff follows, are not laws. By law they should abide rules, but not necessarily, that depends on the judge and the interpretation as I know from watching TV court. Guys using the BoR defense may not work, as they will get smarter, and keep us locked up with more BS on interpretation of the BoR...ect.

A8 "...Nor cruel and unusual punishments inflicted." Invega... and so are the rest of these 1st gen, 2nd gen atypical... name changing 3rd gen, 4th gen...

A4 "The right of the people to be secure in their persons, houses, papers, and effects, against unreasonable searches and seizures, shall not be violated, and no warrants shall issue, but upon probable cause, supported by oath or affirmation." Asking about a persons personal life, and refusal may get subjected to an unreasonable search. I suppose extending the hold on the person, saying that they are a danger because of not speaking with the doctor...

A5 "No person shall be held to answer for a capital, or otherwise infamous crime, unless on a presentment or indictment of a grand jury..." Except when it comes to Mental Health, because there is no crime to begin with, which goes back to A4.

A9 "The enumeration in the Constitution, of certain rights, shall not be construed to deny or disparage others retained by the people."

A1 "Congress shall make no law respecting an establishment of religion or prohibiting the free exercise thereof..." What is your religion guys? If you don't have one, find one. Scientology? They can not prohibit religion through forced drugging. https://ronsorg.ch/wp-content/uploads/Dianetics-Modern-Science-Of-Mental-Health.pdf

PS
There is power in numbers. There is power among us in numbers. A single man will never win this situation?.. Please everyday just exercise, eat good, don't leave me and the rest of us here all alone...it happens everyday... we need to come together. I am here for you, I will always be, whether my mind isn't but you will always be in my heart. Push yourself to the limit. I can tell you that I have truly significantly improved after my single shot. It has been 3 months, and I am nearly back, guys I exercise (HARD) and eat good, I did this all without hope, I am hopeless, but I am doing it anyway, and I am recovering, and there is hope you will too, if that thing didn't kill you instantly, or in a few months, then you can recover from the worst of it, and being here means that you did survive it. Things am doing to stay strong: I am exercising, eating healthy, doing things to simulate the mind, i.e. games, books, brain training, playing chess, listen to music. I like listening to rock music, linkin park is a good band. Learn to play CHESS guys, it is a good game. Please don't let my writing get wasted, I wrote it because I know it will do good. Please improve on what I said...

Love.
 
I didn't take Invega Sustenna, but rather Zyprexa (another antipsychotic), and I have the same symptoms as the people in this thread - no motivation, impaired sense of pleasure, etc. I've been off of Zyprexa for 11 months, and I have yet to notice any significant improvement. This is just speculation, but I wonder if maybe these medications permanently altered our epigenetics so that the drugs turned on/off certain genes that gave rise to our symptoms. I actually asked a doctor this very question (specifically about Zyprexa, not Invega), and he said "your epigenetics will not be altered by this pharmaceutical." Yet, on the other hand, I've heard other experts (mainly chiropractors) suggest that drugs may alter epigenetic homeostasis - kind of like how certain individuals are likely develop permanent psychotic disorders from prolonged marijuana intoxication. In any case I've read conflicting information in the PubMed literature about whether these changes are transitory or permanent.
 
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I would like to say that it has taken me ten full months since my last injection to start feeling better. Now I am almost fully healed. My insomnia was very bad and it remained so for the past 9 months. However, it's almost gone now and so is the minor lack of pleasure I experienced. Hang in there everyone, better times will come.

I used to post here when I was very ill but I stopped as I got better. I did not want to revisit this chapter in my life.
 
AbleArcher83 said:
I would like to say that it has taken me ten full months since my last injection to start feeling better. Now I am almost fully healed. My insomnia was very bad and it remained so for the past 9 months. However, it's almost gone now and so is the minor lack of pleasure I experienced. Hang in there everyone, better times will come.

I used to post here when I was very ill but I stopped as I got better. I did not want to revisit this chapter in my life.
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Minor lack of pleasure? At my worst, the first couple months after getting off the medicine, I had an extreme lack of pleasure. I would just sit and stare blankly and not even attempt to entertain myself because it did nothing. Weed wasn't even getting me high. I can't try it again because I am going to be a CDL driver. However I did/do try drinking and noticed I'm really not even getting drunk. Did you experience any of this? Surely the ability to catch a buzz comes back right? I am 5 months off the medicine and I notice small improvements. I have faith as the brain has an amazingability to heal itself, and I am still young and I managed to stay thin so I think those are all good signs. I hope everyone is doing well.
 
I'm taking liposomal glutathione that I get from my naturopathic doctor, and it helps me a little bit. Here's a quote I found from a medical doctor about glutathione and dopamine receptor sensitivity: Dr. Perlmutter: "Eighty to ninety percent improve dramatically. It's felt that the mechanism that allows it to work is in increasing the sensitivity to certain receptors to dopamine. Glutathione doesn't raise dopamine levels, but it allows the dopamine in the brain to be more effective. That's not a new idea in medicine. Diabetic drugs work not by increasing insulin, but by increasing the receptors to insulin. Glutathione not only increases sensitivity to dopamine, but also to serotonin, which may explain why many of our depressed PD patients have a remarkable improvement." Source: http://www.prozactruth.com/glutathione.htm It may be wise to consult a naturopathic doctor who provides glutathione therapy. The most effective form of oral glutathione supplementation is liposomal glutathione.
 
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Please Help

I am currently working at a boxing gym and I also live there. The boss and other trainers think that I am acting this way because of other drugs. I am asking for help that people comment below about what invega does to you regarding being exhausted, lethargic, unmotivated, poor hygeine, non creativity, non enjoyment of things. Please comment to this and in short tell them what this drug does to you!
 
jennefren said:
I am currently working at a boxing gym and I also live there. The boss and other trainers think that I am acting this way because of other drugs. I am asking for help that people comment below about what invega does to you regarding being exhausted, lethargic, unmotivated, poor hygeine, non creativity, non enjoyment of things. Please comment to this and in short tell them what this drug does to you!
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Response: Invega is a majorly disabling drug. By blockading d2 dopamine receptors it renders the user debilitated, demoralized, and de-energized. It disrupts the limbic system in the brain which removes the pleasure from life and blocks cognition. It does this by blocking d2 dopamine receptors in the brain, which is HUGE in its effects. Most notabley ,it greatly diminished signaling in the frontal cortex and basal ganglia. This eliminates personality, will, motivation, co-ordination, and drive to move about. Basically, the signals are there but the receivers are broken. The mind/body go numb,then from lack of stimulation eventually the signals die out. Think about what this means, this is the horrible process of a person watching nerve disability and breakdown in their own body. Invega is a nerve poison that makes it impossible to enjoy music, the body go limp, and the mind go empty, dull, and useless. People who have had invega find it difficult to express themselves, make decisions or plan for themselves due to brain damage in the frontal cortex. It is very important they should be made comfortable and treated with sympathy, kindness, and dignity during their trial with a deadly nerve poison which induces great suffering.


TL;DR: Invega is serious chemical straight-jacket that restrains you mentally,physically, and spiritually in a profound way. You will no longer experience emotions, fun, or pleasure which makes life very difficult and uncomfortable. Since Invega is an artificial drug, this state of being is unrelatable and unheard of for most people, therefore they cannot sympathize or show proper compassion. This is VERY unfair and needs to be addressed. Invega victims are disabled cripples ungoing sincere misery and deserve to be treated with kindness.
 
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Hi Jenne,

I know this is tough the first few months, but it does get better, very slowly, I am struggling here too, 15 weeks after my shot. You see the oil that drug comes in takes about 3 weeks to metabolize and then the drug starts building up to the the level in blood, slowly, some drug goes out through urine while more gets released. So if your last shot was 1 month ago, you are just about getting the drug going through your system now. The best you can do here is some light exercise, good supplements, and food. Avoid things that stress and scare you. Stop caring about anyone, just care about your self, and you will make through the worst of it... nothing but scars.
If you want, you can drink 2-3 cups of green tea a day. It is a natural diuretic, and can help you go to the restroom more often. Also, remember to drink plenty of water, make sure that it doesn't have fluoride in it. Drinking more water than you are going, should help with clearing the drug out. Sweating through exercise will clear out the drug. You are lucky to be in a MMA gym, I also like to do martial arts once a week, that stuff really rocks the body.


So, here is what I know, and this may be the harsh news some of you don't want to hear, but it is the truth, and possibly it will help you with how to manage now after the shot. This drug is a tranquilizer, will make you very weak for a long time (it probably just kills the nerve synapses, so waiting for it to come off and be ineffective is not going to help), and that just makes life harder, exercise impossible. The chemical probably works just like cocaine, and is a harsher, longer lasting, exact copy of it, except instead of enhancing receptors from sensing dopamine and serotonin, it desensitizes them. For the first few weeks it actually acts like a SSRI, like the Pdoc who gave me the shot said it was, but once that ends and the receptors are being killed off, the real effect of the drug comes into play. You will notice that you have very constricted pupils. This is mainly due to not having serotonin, or dead serotonin receptors. Maybe noticing pupil size could help with indicating recovery, I remember I had very dilated natural eyes before the shot, now they are pin size holes. I guess that pretty much once this drug attaches to the receptors D2... HTPs, the receptor is dead completely. And that leads to very high volume of brain shrinkage. Best way to keep generating new receptors and up-regulating them as quickly as possible to combat this is through exercise and brain training games, being a kid again and going through the growing up process again. Supplements will help too. BUT, mainly this is a tranquilizer for the hypothalamus and pituitary gland, so exercise will be very important here as that helps with keeping the hypothalamus and pituitary gland healthy. The drug does effect everything else, like the whole brain and the peripheral nervous system, D2 receptors are also in the pancreas, exercise should help with everything for the organs of your body, the muscles, and the hormones. So anyway, you are going to experience severe hormone changes, like you are now. I for example was unable to grow a beard 6 weeks out, my face become round, now 15 weeks after my beard is growing but at 1/3rd the pace, face is getting back into shape. Your growth hormones, sex hormones, TSH T3 T4... all your hormones will be effected DRASTICALLY, endocrine organs will be damaged severely. It increases prolactin, which is the big one that I hate. However, 15 weeks out, my libido has vastly improved, and like it said, the beard is picking up pace is growing back, body hair is coming back... My motivation is also improving along with stamina and lethargy. But as for the muscle weakness, lack of muscle growth and soreness, feeling the heaviness of intelligence decline, I suppose that will go away after 3 years of lifting weights, good brain training, and rebuilding the nerve connections. The white matter is the cells, and grey matter is the synapses, the chemical kills the grey matter first, so just trying to keep the synapses from dying will greatly help with keeping brain mass, and that is easier to do than saving white matter. I read that the decrease in testosterone for rats did not improve back to baseline even after the chemical was discontinued over a long period of time, but it did increase somewhat from the lowest soon after the drug was gone. As far as the hormones go, I can see not being able to get sore, or build muscle is going to be hard one for me. Perhaps going to an endocrinologist for hormonal issues and getting cabergoline for might help with repairing the damage done after the drug is gone sooner, and help with keeping the brain cells alive. I personally suppose, I might get cabergoline too after a while EDIT: Or probably Glutathione first, only for a few weeks or so, just to see if that speeds up the process of getting better.

...Who knows, as humans, we are intelligent enough to know how to increase brains and intelligence, so if we keep at the good stuff i.e. exercise and brain training... Like I said, just keep keep trying to re-gen the receptors. The chemical stays attached to the cells for a very very long time. I mean risperidone has half life of 3 hours while 9-hydroxyrisperidone has a half life of 30 hours. Invega is a life sentence. You are going to have to get up and do something about it. Good luck, I'm here with you on your journey.
 
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Hey All,

Thought I'd return to share some positive news. At 4 months off antipsychotics I made a huge recovery. Imagination and creativity returned; I felt happy and energetic once more.

Recovery is certainly possible.

I spent 2 years in isolation. Dumb. Real dumb. It's been difficult to return to normal human conversations... Parts of my brain don't work like they once did. I don't believe any damage is permanent though.

Best wishes to those still suffering

ZM
 
@Zombiemode- - I thought you were off of APs for much longer, like 11 or 12 monthes? Did you have to go back on or something? How much did you do in total?
 
No it's not a virus. Maybe your right about fluorine (-) attracting calcium (+), but virus are DNA sequences themselves, and even if Aps would bind to DNA, a virus or molecule would need some kind of process to cross the nuclei.
 
It took a few months of pills, but one injection for the disAbilify to reach full antagonistic effect.
 
Is there anything we all have in common I wonder? I'm trying to figure out why some of us are affected so negatively, while others I know were not affected negatively. Are all of us young-ish? Were any of us drug addicts like myself? Were all of us struggling with depression prior to this? Did anyone else take this really close to or on top of other APs or other meds? It just seems like there must be a reason for a group of us to have been affected the way we have been. Maybe it's just completely random or based on our biochemistry? I noticed a lot of us who were addicts seemingly couldn't catch a buzz from anything after this experience, what do you guys make of that? I noticed a couple days after I got the "loading dose" I was able to get high much to my relief at the time. One week later when I got my next shot, I was unable to get high or drunk... or even feel relaxed from a cigarette for that matter. I don't do drugs anymore or smoke but I am noticing alcohol is starting to work again, I'm almost 6 months out thankfully. No matter what lets try to stay positive everyone! For example, one good thing I take from this is being able to kick my 16 year drug addiction. Due to the effects of drugs not working for me I was able to quit. Now I am going to CDL school to be a truck driver. This is something I always wanted to do, but drugs held me back. We will come out better on the other side guys. Stay strong. If nothing else just keep in mind this experience is building our character and making us stronger. We will come out better for it on the other side. On an unrelated matter, I just tried kratom for the first time and it does seem to be helping. If anyone ever needs to talk PM me, I can give my number too. Thanks for reading guys, and be well!
 
I took about the last month just vegging around the house and walking when I needed to. I had been experience pretty intense uneasiness starting around mid-december which forced me out of work. After the last month of Netflixing I have begun to venture out for various reasons. It may be the spring Sun but I am starting to feel the light in my life once again. This is really good news because frankly, I was feeling defeated by Invega, and probably suggested that in my posts. I am starting to believe that if I give a good push, and I have realistic expectations, that over the next three monthes I could get my head above water.

@Copperdome - I think you are asking some good questions but I would venture to guess Invega effects everyone about the same. People's standard over what constitute's functional or acceptable health vary greatly, probably. Like other people, I received the 234 initial then the 134 booster only (if that gives you some idea of my dose((160 lb 5'11 male.)) The brain is very subtle , and the drug changes what we are used to. Maybe some people don't use their 5-ht7 receptors much anyway!
I think I just have to let this whole experience go and get over being bitter about what the poison did to me. I am starting to believe like you that if I have a positive attitude I can see this thing through.

Anyways- I don't want to overcomplicate things by ranting over this, I'll just say that I'm going to start doing my best now that I'm starting to see the light crack Ithrough this experience finally. I believe the poison acts as a real physical/mental straight jacket when it's in your system but after that? It's up to you to make the push and do the things that would normally get you back to solid health. I encourage you all to find the balance between being gentle/reasonable and pushing yourselves in the rehabilitation from this major tranquilizer. I believe it is possible that the body regains function after the 6-7 month period, it's up to us to yank it out of the ditch. I am going to do my best to be consistent in my effort from now on, and I will be certain to post my progress as it is helpful. Thanks for your well wishes and I wish everybody reading this the best in health.

I'm looking to start a new career maybe go in to become a customs official, I hear they are hiring right now because of Trump! I think that'd be a good gig if I could get it.
 
@copperdone, I'm so piss off I actually need an Ap lol. They threat like I'm schizophrenic, but the way the stuff works it's the perfect tool to keep you away from the scene. I was court ordered after acting like a complete moron, but really I didn't knew they were waiting for me at the psych ward. People affected positively by Aps are on higher dosages.

I'm a recovering addict, but I grew up. I'm not really having fun while sober, but I'm no hardcore user either.

@invegauser, I don't believe in the calcium build-up theory, it's a strong antagonist for me, it's just as effective as it gets

@nnnbbvvv Thanks for giving us hope
 
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I never did any drugs in my life guys. And neither did I plan on ever taking them. I feel the same exact thing all the rest of you feel. Ironically, I was never in psychosis either. They just gave me this shot.

Be positive and live positively, live to get better, live to improve everyday, live to love and cherish. BUT never move on from this experience, I mean, never forget about it, like my fortune cookie 3 days ago said "Live for Today but never forget Yesterday".
 
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