To my knowledge, antipsychotics may lead to brain shrinkage, but only to a very small, insignificant amount. Can you provide a source? Thanks.
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Mental Health Coming Off Invega Sustenna (Paliperidone) v.2
- Thread starter TrustInGod
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www.ncbi.nlm.nih.gov/pubmed/15756305
Study in monkeys up to 20% shrinkage ?. Studies with people are often falsify by saying that the major loss of gray and white matter is due to the mental illness itself ?.
I think APs are worse than some street drugs and nobody takes this stuff just to be more clever or to improve physical strenght. There is no data in sports about any athlete that has taken this drug to win a gold medal or a new world record ( contrary to steroids, meldonium, etc...), it sounds hilarious.
APs ?? are venom ?
That study is over ten years old, and isn't in humans or chimps.
This is a longitundinal study with humans, conducted by Cambridge, and is less than two years old: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101689 results: "The mean annual total brain volume reduction was 0.69% in participants with schizophrenia and 0.49% in control participants". That means .2% more per year.
This is a longitundinal study with humans, conducted by Cambridge, and is less than two years old: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101689 results: "The mean annual total brain volume reduction was 0.69% in participants with schizophrenia and 0.49% in control participants". That means .2% more per year.
iridescentblack
Bluelighter
I thought I'd share some information that I believe has led me closer to "recovery"... and other stuff
So I've been drinking coconut water almost every day ever since October or November of last year. I also eat spicy food almost every day. Not sure if these two things have sped things along but it sure seems like it. I can finally eat some of the foods I haven't been able to eat for so long because of allergy-like symptoms... raw carrots, cucumbers, broccoli and bell peppers... peaches, nectarines, apricots, mangoes, plums, pears, apples, and cherries. My creativity is coming back. 'Finally able to draw and my drawings don't suck nearly as much as they used to. Playing synthesizer again and it's sounding amazing. Not getting headaches as often. Loads of energy.
So I've been drinking coconut water almost every day ever since October or November of last year. I also eat spicy food almost every day. Not sure if these two things have sped things along but it sure seems like it. I can finally eat some of the foods I haven't been able to eat for so long because of allergy-like symptoms... raw carrots, cucumbers, broccoli and bell peppers... peaches, nectarines, apricots, mangoes, plums, pears, apples, and cherries. My creativity is coming back. 'Finally able to draw and my drawings don't suck nearly as much as they used to. Playing synthesizer again and it's sounding amazing. Not getting headaches as often. Loads of energy.
Aiden21
Bluelighter
http://www.ncbi.nlm.nih.gov/books/NBK1853/
Article about the receptors that bind with our dopamine after invega. Invega nullifies the decensitized and recensitizing process and internalization of these.
In other words, it makes learning impossible because you can't recycle new information nor can you challenge another mentally.
Think about it like this. Someone sniffles to decenditize another, no one reacts except you, then someone does something that decensitizes you. You then take it internally and recensitize your reaction(correcting your error). Then someone gets the "oh" moment.
No "oh" moments for invega sustenna patients.
Decensitizing and recensitizing because without it we would still be eating bugs and throwing poo.
Article about the receptors that bind with our dopamine after invega. Invega nullifies the decensitized and recensitizing process and internalization of these.
In other words, it makes learning impossible because you can't recycle new information nor can you challenge another mentally.
Think about it like this. Someone sniffles to decenditize another, no one reacts except you, then someone does something that decensitizes you. You then take it internally and recensitize your reaction(correcting your error). Then someone gets the "oh" moment.
No "oh" moments for invega sustenna patients.
Decensitizing and recensitizing because without it we would still be eating bugs and throwing poo.
To take years to recover from a medicine is a fucking joke especially when your not even skitzo on the other hand I was diagnosed with bipolar disorder so I'm getting dragged down with the depression of that too which makes my days suck and for that I'm taking 10mg abilify and 1500mg moodstabiliser per day does anyone else have bipolar here?
On a lighter note did anyone experience reduced testicular size since the injections? Mine have got smaller in size significantly since it begun.
On a lighter note did anyone experience reduced testicular size since the injections? Mine have got smaller in size significantly since it begun.
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iridescentblack
Bluelighter
caffeine intolerance, tinnitus (though it's less frequent), fast resting and active heart beat, heart beats very strong when laying down flat on my back, low strength (but not as bad), dry mouth/mouth opens up during sleeping (but it's getting better), and muscle twitches and spasms (though not as common).
Did you used to have loss of emotion and cognitive decline but it got better?
iridescentblack
Bluelighter
@Gdvffh I have some mental issues still lingering like inability to focus and concentrate (but just like a lot of things, those have gotten a lot better), memory issues (usually linked with anxiety where - if I talk about something for a long time and for whatever reason anxiety builds up during that period - I tend to forget what I'm talking about).
I sometimes forget to include these issues because I'm not sure if they are related to spice (synthetic marijuana), the injection medications, or a combination of both. Either way, like I said, the seem to be getting better so it might have been the injection meds or a combination of that and spice.
I sometimes forget to include these issues because I'm not sure if they are related to spice (synthetic marijuana), the injection medications, or a combination of both. Either way, like I said, the seem to be getting better so it might have been the injection meds or a combination of that and spice.
Okay i am just going to put a note of caution in here and say that using Alcohol while suffering from a mental illness much less treating a mental illness with Alcohol is possibly one of the worst things you can possibly do. Along with the standard brain and organ damage Alcohol makes just about every mental illness far worse. As bad a problem as they can cause if not used right Benzos would be a much safer option as atleast they have a place in treating mental illness. I suffer from Bipolar disorder as well as anxiety and have been on Risperidone (of which Paliperidone aka Invega is the only major active metabolite of) alot in the past in oral form but i find both Quetiapine and especially Olanzapine to work much better in treating my symptoms and have less unwanted side effects so these days i take Quetiapine for it.
Alcohol even in fairly low amounts makes all my symptoms far worse and i would say it's the worst drug for me in terms of aggravating symptoms. While stimulants especially Cocaine in IV or Crack form are bad for making my symptoms worse Alcohol is still a bigger offender in this regard as as long as i don't over do it and get a good nights sleep and eat properly i can do stims on occasion without too many consequences. However any amount of Alcohol that actually makes me feel anything (this usually takes atleast 8 drinks) also at the very least fucks my sleep up severely causing insomnia or vivid nightmares and shitty sleep where it feels like i haven't slept at all. Not to mention the increased anxiety and general feeling of feeling fucked up that can last a good day or 2 after ingestion. Some of the worst Mixed states i have had have been due to Alcohol with no other drugs involved.
Aiden21
Bluelighter
android, did you get an invega sustenna injection? And if so, did cocaine return any prior feelings?
Week 34 off the poison
One more week till half life five and things seem to be improving. Starting to try and get more active and working on my fitness slowly. Hopefully I've got no brain damage from the poison and my brain does seem to be getting less groggy as each week passes, still feel a bit dumb, but I'm hoping to be recovered at half life six like decisive.
My plan for today is to get my garden done then be in the beer garden this afternoon chilling with a few joints, not bad considering at Christmas I was almost suicidal and couldn't even face going out, maybe I'll just chill in front of the tv, I'll see what state I'm in after finishing the gardening.
It's a marathon, not a sprint recovering from the poison
One more week till half life five and things seem to be improving. Starting to try and get more active and working on my fitness slowly. Hopefully I've got no brain damage from the poison and my brain does seem to be getting less groggy as each week passes, still feel a bit dumb, but I'm hoping to be recovered at half life six like decisive.
My plan for today is to get my garden done then be in the beer garden this afternoon chilling with a few joints, not bad considering at Christmas I was almost suicidal and couldn't even face going out, maybe I'll just chill in front of the tv, I'll see what state I'm in after finishing the gardening.
It's a marathon, not a sprint recovering from the poison
Here is a post I read on another thread and I can relate to it very well.
Quote:
This isn't very scientific but I can tell you from personal experience that the answer to both of these questions is an emphatic YES! I was a normal college student before it all happened. I got straight A's in school, had lots of friends, and lots of hobbies and interests. One day I decided to quit smoking pot and drinking coffe (both of which I did to a rediculous extent). This resulted in me not being able to sleep for over a week and a subsequent nervous breakdown complete with delusions and possibly hallucinations. I ended up trying to kill myself.
I was hospitalized under the Baker Act, a Florida law which allows the state to incarcerate you in a mental facility for up to three days if you constitute a risk to yourself and others. They were very quick to diagnose me with Bipolar Type II without even talking to me and very minimal observation.
They prescribed me Abilify (ariprizole) which I took religiously. This drug decreased the psychotic symptoms but gave me severe akathesia and made it impossible to sleep. After staying awake 24/7 for almost a month even the effects of the aripirizole couldn't keep me sane. I ended up being forced into the hospital by my parents where I signed a contract which allowed them to keep me until the doctor said I was fit for release. This was the biggest mistake I've made in my entire life.
The hospital took me of the Abilify and put me an injection of Geodon (ziprazidone) and gave me Seroquel (quetiapine) at night which did allow me to sleep. I awoke the next day groggy as Hell and barely able to move. This is the first time I remember feeling like a zombie. I barely read or compose a thought and someone had to help me order my breakfast and dinner for the next day.
For whatever reason they switched me from Geodon (unknown dosage) to Depakote (divalproex) 500mg, Risperdal (risperidon) 3mg, and cogentin (benztropine), twice daily. At night they added Restoril (temazepam) to the mix to knock me out. These medications were supplimented with various medications that were given to me at different times for seemingly no reason and also a few unkown injections.
I spent 23 days in the hospital on this toxic cocktail. It was a living Hell. I was barely able to function on even the most basic level. I couldn't talk, think, do anything. I shuffled around the hospital all day speaking in one word sentences. The simplest tasks such as taking a shower or putting on my clothes became overwhelming chores. I was a complete zombie. I spoke in monotone, had absolutely no emotions, and the cognition of a lesser species. I remember once trying to learn how to play Hearts with some guys in the activity room. This was an exercise in complete futility. Despite all of this, my delusions (which I'm still not comfortable enough to go into) persisted and actually worsened. I still have a piece of paper where I tried to write down a list of tasks to get me through the most basic task: waking up in the morning. It read something like this:
1. Wake up
2. Put on socks
3. Get out of bed
4. Put on shirt
5. Get in shower
My brother said once I when I came to visit I was shuffling around and my pants fell down and I didnt even notice.
The hospital was the most terrible experience of my life. Everything was dictated by threats. "Take this medicine or we're gonna shoot it up your ass." "Eat your food or we're gonna strap you down to a table and shove a tube down your throat." "Take your medicine or we're going to mark you as non-compliant and put you in an institution."
Anyway, I finally got out of the hospital. God knows what criteria upon which they based their decision. I was much worse off leaving than I was entering the hospital. They had taken a normal kid with a severe case of sleep deprivation and turned him into a fucking zombie.
I continued my regimen of anti-psychotics under the supervison of my psychiatrist and my zombie-like state and delusions persisted for months afterward. When it became apparent that I was not getting any better from my medications the psychiatrist switched took me off of the Depakote and put me on Zyprexa (olanzapine) which I took with the Respridal and cogentin. Eventually he took me off of everything and put me on the Zyprexa alone. I started to regain a little bit of my previous cognitive ability but for all intents and purposes I was still a zombie.
It wasn't until I unilaterally took myself off of everything that I started to feel better. I did this despite the fact that my mother threatened me with putting me back into the hospital if I stopped. Well after a while I began to regain my animation and become something that resembled a human again. And, whadayaknow, my delusions started to go away too.
I took myself off of my medication somewhere in August or September. My state has improved to the point that I now percieve reality in the same way I always did before the psychotic episode and I have regained a lot of my cognitive ability. That being said, I have not regained my emotions. I am emotionally less complex than my dog. I can no longer feel love, compassion, happiness, satisfaction, enjoyment, comfort, elation, warmth, empathy. sympathy, fear, anxiety, rage, emotional attachment, or anything like that. I have trouble even telling my own mother I love her because I just don't feel it anymore. I can laugh occassionally but its usually no more than a "heh" and most of the time its more of a conditioned response than anything else. I've lost my sense of humor. I don't go out, I don't talk to my friends anymore, I don't watch televison, and music has no appeal to me anymore whatsoever. I have lost my completely lost my sex drive. I don't feel like I'll ever be able to excel in school again as I seem to have experienced a significant dulling of the intellect. I have a constant headache and ringing in my ears every waking moment. I sleep 12+ hours a night (or day depending on my sleep pattern of the week) and I still wake up feeling like shit.
The only emotions I realy feel anmymore are bitterness, hatred, and sadness. I feel bitter when I see normal people being laughing, being happy, and socializing. I feel hatred towards the hospital staff psychiatrist that ruined my life, and I feel sadness when I am reminded of my previous life and everything that I've lost.
In conclusion these are horrible drugs which took a smart, funny, vibrant young man and completely ruined his life. God only knows how many people are pacing around mental hospitals as a result of this garbage. The people who push this shit should be thrown in jail for murder. They took something from me more valuable than anything else on earth: my soul. I might as well be dead
Quote:
This isn't very scientific but I can tell you from personal experience that the answer to both of these questions is an emphatic YES! I was a normal college student before it all happened. I got straight A's in school, had lots of friends, and lots of hobbies and interests. One day I decided to quit smoking pot and drinking coffe (both of which I did to a rediculous extent). This resulted in me not being able to sleep for over a week and a subsequent nervous breakdown complete with delusions and possibly hallucinations. I ended up trying to kill myself.
I was hospitalized under the Baker Act, a Florida law which allows the state to incarcerate you in a mental facility for up to three days if you constitute a risk to yourself and others. They were very quick to diagnose me with Bipolar Type II without even talking to me and very minimal observation.
They prescribed me Abilify (ariprizole) which I took religiously. This drug decreased the psychotic symptoms but gave me severe akathesia and made it impossible to sleep. After staying awake 24/7 for almost a month even the effects of the aripirizole couldn't keep me sane. I ended up being forced into the hospital by my parents where I signed a contract which allowed them to keep me until the doctor said I was fit for release. This was the biggest mistake I've made in my entire life.
The hospital took me of the Abilify and put me an injection of Geodon (ziprazidone) and gave me Seroquel (quetiapine) at night which did allow me to sleep. I awoke the next day groggy as Hell and barely able to move. This is the first time I remember feeling like a zombie. I barely read or compose a thought and someone had to help me order my breakfast and dinner for the next day.
For whatever reason they switched me from Geodon (unknown dosage) to Depakote (divalproex) 500mg, Risperdal (risperidon) 3mg, and cogentin (benztropine), twice daily. At night they added Restoril (temazepam) to the mix to knock me out. These medications were supplimented with various medications that were given to me at different times for seemingly no reason and also a few unkown injections.
I spent 23 days in the hospital on this toxic cocktail. It was a living Hell. I was barely able to function on even the most basic level. I couldn't talk, think, do anything. I shuffled around the hospital all day speaking in one word sentences. The simplest tasks such as taking a shower or putting on my clothes became overwhelming chores. I was a complete zombie. I spoke in monotone, had absolutely no emotions, and the cognition of a lesser species. I remember once trying to learn how to play Hearts with some guys in the activity room. This was an exercise in complete futility. Despite all of this, my delusions (which I'm still not comfortable enough to go into) persisted and actually worsened. I still have a piece of paper where I tried to write down a list of tasks to get me through the most basic task: waking up in the morning. It read something like this:
1. Wake up
2. Put on socks
3. Get out of bed
4. Put on shirt
5. Get in shower
My brother said once I when I came to visit I was shuffling around and my pants fell down and I didnt even notice.
The hospital was the most terrible experience of my life. Everything was dictated by threats. "Take this medicine or we're gonna shoot it up your ass." "Eat your food or we're gonna strap you down to a table and shove a tube down your throat." "Take your medicine or we're going to mark you as non-compliant and put you in an institution."
Anyway, I finally got out of the hospital. God knows what criteria upon which they based their decision. I was much worse off leaving than I was entering the hospital. They had taken a normal kid with a severe case of sleep deprivation and turned him into a fucking zombie.
I continued my regimen of anti-psychotics under the supervison of my psychiatrist and my zombie-like state and delusions persisted for months afterward. When it became apparent that I was not getting any better from my medications the psychiatrist switched took me off of the Depakote and put me on Zyprexa (olanzapine) which I took with the Respridal and cogentin. Eventually he took me off of everything and put me on the Zyprexa alone. I started to regain a little bit of my previous cognitive ability but for all intents and purposes I was still a zombie.
It wasn't until I unilaterally took myself off of everything that I started to feel better. I did this despite the fact that my mother threatened me with putting me back into the hospital if I stopped. Well after a while I began to regain my animation and become something that resembled a human again. And, whadayaknow, my delusions started to go away too.
I took myself off of my medication somewhere in August or September. My state has improved to the point that I now percieve reality in the same way I always did before the psychotic episode and I have regained a lot of my cognitive ability. That being said, I have not regained my emotions. I am emotionally less complex than my dog. I can no longer feel love, compassion, happiness, satisfaction, enjoyment, comfort, elation, warmth, empathy. sympathy, fear, anxiety, rage, emotional attachment, or anything like that. I have trouble even telling my own mother I love her because I just don't feel it anymore. I can laugh occassionally but its usually no more than a "heh" and most of the time its more of a conditioned response than anything else. I've lost my sense of humor. I don't go out, I don't talk to my friends anymore, I don't watch televison, and music has no appeal to me anymore whatsoever. I have lost my completely lost my sex drive. I don't feel like I'll ever be able to excel in school again as I seem to have experienced a significant dulling of the intellect. I have a constant headache and ringing in my ears every waking moment. I sleep 12+ hours a night (or day depending on my sleep pattern of the week) and I still wake up feeling like shit.
The only emotions I realy feel anmymore are bitterness, hatred, and sadness. I feel bitter when I see normal people being laughing, being happy, and socializing. I feel hatred towards the hospital staff psychiatrist that ruined my life, and I feel sadness when I am reminded of my previous life and everything that I've lost.
In conclusion these are horrible drugs which took a smart, funny, vibrant young man and completely ruined his life. God only knows how many people are pacing around mental hospitals as a result of this garbage. The people who push this shit should be thrown in jail for murder. They took something from me more valuable than anything else on earth: my soul. I might as well be dead
PhuckInvegga
Bluelighter
- Joined
- Mar 15, 2016
- Messages
- 74
Yup, that sums it up pretty well. I feel like my story coincides perfectly. Funny cuz I remember trying to play cards too and feeling so mentally retarded I couldn't even understand texas holdem, a game I already knew.. The mental institutions are such fucked up places, full of threats. They're run by complete cowards who get sick pleasure from forcing this stuff on you, and love to ignore you or in my case smile and ignore you as you desperately plead for no more drugs. Panic and despair flooded my body 24/7. After 2 weeks of feeling this way, trying everything including changing my meds 4 times, refusing them altogether, losing the evaluation and continue to be forced.. The way I felt was so horrible, I knew that God didn't exist because even Satan would've felt sorry and intervened this human torture by now. I stared out the window and said goodbye to the world as I began to accept my fate of suicide, and the sweet relief of death, the only possible escape. Then by some divine intervention they said okay your released, but only if you take Invega. That was 4 months ago.
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I Cant stand my symptoms anymore. I cant... I dont want to make a big show here but the thought of suicide is still so present. NOONE could stand this torture that i am going through. everybody recovers here and I still have anxiety attacks that make me NUTS AS HELL. Panic, fear I cant even walk alone or drive a car alone. I have whining attacks i am not myself anymore. I lost myself. There is nothing I want more than getting my old self back. Today I took sleeping pills cause I couldnt stand my condition. I slept a long time. I wanna die. I Feel the same way as PhuckInvega does. How can God let this happen? Psychiatrie MUST DIE. I felt so lost there, I even lost my mom because she believed the doctors more than her daughter. When I went to the hospital forcefully these psychiatrists laughed at me , I told them I go nuts with medications and that I couldnt stand this torture that is coming from the meds. alway panic, always fear, anxiety, pain, depression. I would give my live for these symptoms to go away but they just dont go away. Plus if something is induced into the muscle it will stay there forever I read this. It will also stay there even if you quit the drug cause the muscle system is different than the belly system when it comes to elimination. 1 year zero improvement. i cant stand it no wmore i lost all hope it will last forever. I am so close to suicide NOONE COULD STAND THIS TORTURE WHAT THESE MEDS DO TO ME NO ONE...not even a slight improvement i am NOT LYING .
I prayed to God but he doesnt help its pure hell. they took a young, funny, beautiful, smart, outgoing, happy girl and turned her into a nothing, not functional person. a person that needs to stand so much that she cant imagine to live anymore . i can no longer feel happy, healthy , excited. i will never heal. here are people that prescribe the same thing and i just want to take my life. these drugs have won it seems like it. 
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