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Mental Health Coming off Invega (paliperidone) injections, v 5.0

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The paliperidone LAI package insert recommends loading doses that result in plasma concentrations approximately equivalent to those of 6 to 12 mg of oral paliperidone ER.7 The package insert also states bridging with oral antipsychotics is not necessary. However, because 4 mg/d oral risperidone is approximately equivalent to 8 mg/d paliperidone ER, recommended loading doses of paliperidone LAI would yield concentrations approximately equivalent to 3 to 6 mg of oral risperidone.9 Especially if the plasma concentrations are closer to 6 mg of paliperidone ER (3 mg of oral risperidone), this may lead to subtherapeutic concentrations in patients who require doses of oral risperidone ≥4 mg/d.
 
apsucks said:
The paliperidone LAI package insert recommends loading doses that result in plasma concentrations approximately equivalent to those of 6 to 12 mg of oral paliperidone ER.7 The package insert also states bridging with oral antipsychotics is not necessary. However, because 4 mg/d oral risperidone is approximately equivalent to 8 mg/d paliperidone ER, recommended loading doses of paliperidone LAI would yield concentrations approximately equivalent to 3 to 6 mg of oral risperidone.9 Especially if the plasma concentrations are closer to 6 mg of paliperidone ER (3 mg of oral risperidone), this may lead to subtherapeutic concentrations in patients who require doses of oral risperidone ≥4 mg/d.
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150mg paliperidone by xeplion J&J docs is equal to 12mg risperidal oral daily.
 
I don’t feel happy, excitement, nervous, nothing. None of the good emotions I don’t feel. I just feel numb and I’m just getting fatter I hate antipsychotics
 
Someone who has been off Invega from more than 12 months? Anyone recovered or to close to recovery?
 
Has anyone tried studying/going to college while on Invega?

I tried community college last year but sitting in a classroom listening for 2 hours and break then another 3 hours was a soul sucker for me. Having no job, no life, no friends means I have no structure in my life and am not use to doing something for hours at a time like normal people can do...

working life is going to be a real shock to my mind and body but go to do what you got to do....
 
apsucks said:
Wouldn't surprise me if its braindamage...

3th shot i got severe crackling sounds in my brain, colours were changing almost like hallucinations and severe depression hit me in waves accompanied with orthostatic intolerance. Back home my muscles over my whole body started twitching from toe to head like really fast. This shit causes braindamages i don't care if its macro or micro it completely ruins your brain. I don't believe in the half life theory and such low amounts of paliperidon still can have any significant impact. Month 2 my blood lvl was 5ng/ml which is low (most people have these levels after 4 months, the other dude had one shot and had 5ng after 4 months). It will probably be lower now going in the 3th month...therapeutic range is above 20..

First 1.5 months my armpits literally smelled like paliperidon..i could smell it in my nose as well that scent has been replaced by another weird chemical smell probably additives which are just as poisonious and fuck you up as well.

Its brain damage and it takes a long time to recover. This drug nukes your striatum/reward centre is why people cannot get high...some people still unable to get high or drunk 1.5 years later after one shot is just completely disgusting and got nothing do with blood levels of paliperidon. It tapers slowly so these aren't withdrawals either. I don't believe its a simple antagonist which will go back to homeostasis these drugs arent even tested for neurotoxicity. There is no sensitivity in nerves anymore everything feels muted or nerfed, i don't feel hot water in my mouth (literally)

I'm sick and tired of this whole situation im on the verge of killing myself...press the reset button and reincarnate somewhere else.
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Sad Schitts Creek GIF by CBC
 
Ihateinvega00 said:
There is a new injection just got approved and it's called invega hafyera. And I really can't believe this. I already hate my life depressed, it feels like for eternity and I don't know what to do with my life. Any advice someone has for me to make it less suffering. Im sorry if I'm being too personal. It's just because I am miserable and is still suffering after many many years being hopeless
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Im just taking invega sustenna and now they have trinza, then hafyera. Then I guess who knows worse and worse. Please is there anyone that can help me to make it less severe my depression
 
Saiyana said:
Has anyone tried studying/going to college while on Invega?

I tried community college last year but sitting in a classroom listening for 2 hours and break then another 3 hours was a soul sucker for me. Having no job, no life, no friends means I have no structure in my life and am not use to doing something for hours at a time like normal people can do...

working life is going to be a real shock to my mind and body but go to do what you got to do....
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It makes me terrified that it feels literally for eternity that my life is miserable. I've taken invega pill form and injection (sustenna) and both were huge difference. Invega pill forms are better then invega sustenna (cannot be compared) and recently they invented 6 month injection. I don't know what to do with my life. Whenever I went to school I just hated my life, whenever I watched a show it was just no enjoyment. I'm only hopeless.
 
welcome to Bluelight Ihateinvega, was reading about that earlier, an ex coworker was on that, she had parkinsonism and couldnt cut hair anymore really drove her mad not able to do all she loved , will say she stopped self harming, pulling her hair and cutting. i hope you find some peace here or atleast some solace with connection of community
 
Robi said:
welcome to Bluelight Ihateinvega, was reading about that earlier, an ex coworker was on that, she had parkinsonism and couldnt cut hair anymore really drove her mad not able to do all she loved , will say she stopped self harming, pulling her hair and cutting. i hope you find some peace here or atleast some solace with connection of community
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Thanks for your kindness. But I don't think its going to help. I just posted in here because theres nothing else I can do. I didn't take the stronger medications like trinza and especially the other one. And I feel like I have the worst life dver.I just want to not exist anymore ,that's all. But thank you for trying to help and I appreciate it
 
Ihateinvega00 said:
Thanks for your kindness. But I don't think its going to help. I just posted in here because theres nothing else I can do. I didn't take the stronger medications like trinza and especially the other one. And I feel like I have the worst life dver.I just want to not exist anymore ,that's all. But thank you for trying to help and I appreciate it
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thats all? your existence is vital,more than you know sweet of heart, youre going to help someone one day, please, i know the feeling of worst life ever, but thats me and working hard to change it, but im not going thru what you are, we all have been in our own personal hells, and yours is very important to me. i hurt when people reach out and share pain, i feel for you, all i have to offer is kindness, and i know you need more than that, few have shown me compassion(in my life) and i didnt care in my darkest hours, but you hold on, theres always light at the end of the tunnel(even if its a fukkn train) you matter i want whats best for you pls stay in touch
 
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Ihateinvega00 said:
Thanks for your kindness. But I don't think its going to help. I just posted in here because theres nothing else I can do. I didn't take the stronger medications like trinza and especially the other one. And I feel like I have the worst life dver.I just want to not exist anymore ,that's all. But thank you for trying to help and I appreciate it
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So you're being forced to take Invega? Is there no way you can stop it, or at the very least switch to another medication?
 
Hey guys
Before antipsychotics i didn t had psychosis
Anyway i got off the last 50 mg to 0 quetiapine and after a period of max 2 months of being off quetiapine i experienced strong psychosis delusions,paranoia,anxiety witch i didn t had before ap
This time i won t go fast from 50 mg to 0
Im thinking taking 50mg for couple of months till i reach 25 mg
When i reached 25 mg i wanna do an extremely slow taper to 0
I wanna remove 1 mg each month to let time for my brain chemistry to become pre psichiatry drugging
 
Marian.username@gmail said:
Hey guys
Before antipsychotics i didn t had psychosis
Anyway i got off the last 50 mg to 0 quetiapine and after a period of max 2 months of being off quetiapine i experienced strong psychosis delusions,paranoia,anxiety witch i didn t had before ap
This time i won t go fast from 50 mg to 0
Im thinking taking 50mg for couple of months till i reach 25 mg
When i reached 25 mg i wanna do an extremely slow taper to 0
I wanna remove 1 mg each month to let time for my brain chemistry to become pre psichiatry drugging
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Whoa! So sorry to hear that quetiapine basically gave you psychosis, it seems? Why were you prescribed it in the first place?
 
Marian.username@gmail said:
Hey guys
Before antipsychotics i didn t had psychosis
Anyway i got off the last 50 mg to 0 quetiapine and after a period of max 2 months of being off quetiapine i experienced strong psychosis delusions,paranoia,anxiety witch i didn t had before ap
This time i won t go fast from 50 mg to 0
Im thinking taking 50mg for couple of months till i reach 25 mg
When i reached 25 mg i wanna do an extremely slow taper to 0
I wanna remove 1 mg each month to let time for my brain chemistry to become pre psichiatry drugging
Click to expand...
That's what I hate about modern medicine. Shoot first, then aim, ask questions later.
I'm so sorry to read that. Please be careful with the taper!
 
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