Jabberwocky
Frumious Bandersnatch
LSD has a higher affinity for HT2a than psilocin. LSD actually has affinity with 8 different serotonin receptor subtypes. It also has affinity for dopamine 1 and 2 subtypes as well as a couple other receptor types (forget which).
I presume (maybe incorrectly, HT2 correct me if I'm wrong?) that some of the psilocin would remain at the HT2a (and 2c) sites. Both chemicals also affect a slightly different profile of receptors, probably in slightly different areas of the brain (although this type of data is just now coming in for drugs like LSD).
Synergism can also occur when one chemical is a monoamine releaser or reuptake inhibitor or if one chemical has MAOI properties or other antagonist properties.
I presume (maybe incorrectly, HT2 correct me if I'm wrong?) that some of the psilocin would remain at the HT2a (and 2c) sites. Both chemicals also affect a slightly different profile of receptors, probably in slightly different areas of the brain (although this type of data is just now coming in for drugs like LSD).
Synergism can also occur when one chemical is a monoamine releaser or reuptake inhibitor or if one chemical has MAOI properties or other antagonist properties.