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[Combo Sub Thread] MDMA and Stimulants - Meth and adderall and amphet... I'm tweakin

^ How so? You switch from adderall to desoxyn and I'd say there's going to be a lot more "euphoria". He doesn't even mention that though, he refers almost completely to side effects.


Vyvanse is NOT dextroamphetamine, you said it yourself. It is a prodrug, which means it must go through the first phase metabolic process to become active. This is similar to the difference between GBL and GHB or adrafinil from modafinil


Adrafinil was discovered in the late 1970s by scientists working with the French pharmaceutical company Group Lafon. First offered in France in 1986 as an experimental treatment for narcolepsy, Lafon later developed modafinil, the primary metabolite of adrafinil. Modafinil possesses greater selective alpha-1 adrenergic activity than adrafinil, without many of adrafinil's common side-effects (stomach pain, skin irritation, anxiety and (with prolonged use) elevated liver enzymes).[2] This makes it important to monitor the liver of an individual using adrafinil for prolonged periods.

(from wiki)
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I could find reports of GBL having a higher side effect portfolio when compared to GHB as well, in fact EZ test designed a whole reagent around that thought. The point is prodrugs do NOT equal their metabolites, while they will often have almost entirely the same effects (due to turning into the same drug) they are often said to be much "dirtier" by those who use them. Not to mention the point of prodrugs like vyvanse is to make drugs "abuse-proof", which obviously doesn't work but makes it MUCH less than ideal when trying to combine with a drug like MDMA
 
Lol folley I've taken vyvanse on and off 6 years. I have an Rx... I've literally taken bottles and bottles. Nothing dirty about it, feels just like a slower peaking dexedrine, longer lasting peak, slower wearing off.

Also - by no means is vyvanse "abuse-proof" lol. That's ludacris. Trust me it's schedule II and rightfully so it fits there well. Trust me I've been there done that and it's only a step short from orally-consumed methamphetamine. Although I'd take d-methamp any day over d-amp.
 
doing xtc with amphatemine/speed

hey guys i wanted to try out XTC combined with Speed/amphatemine

I got a very good pill a Blue defqon 200 mg of mdma en some speed from my fried that went nuts on it not sure the % tho... i do know its clean for sure.

So how do i start to get the best effect from this?

And what are you supposed to feel from combining these 2 drugs together?
 
Well my friend , this is the oldest ravers combo ever know to man kind and what it will do is make you want to dance talk dance talk dance talk dance talk dance talk dance talk and then dance and talk some more. Both of these drugs are speedy drugs, expect some more side effects than one without the other but they will probably also compliment each other. more euphoria, more speedines, more fun but also a shittier comedown that's for sure :) Blue defqons are pretty strong . What I would do is just take a half and then around two hours later take another half and also snort small lines throught the night. But that's unhealthy and Im pretty unhealthy too.
 
Unhealthy why is it unhealthy then? i know taking drugs is already unhealthy but does this combination make it more worse ?
 
Personally, I'd just take MDMA and mix a decent amount of caffeine for a stimulated roll. Taking two strong stimulants could really give you some shitty after-effects, despite the high being fun. If you've got blue defqons only take 1/2 to 3/4 as they are strong fuckers. Mixing a whole one with speed is a recipe for gurning madness and a difficult comedown. MDMA or speed are both fun and enjoyable on their own. It's better, from a HR perspective, to take either alone.
 
Meth can completely over power an MDMA experience. Caffeine or even pseudo ephedrine would be much better and pseudo was used to cut pills back in the day and make them more "speedy". If you'd like to waste the money on your 200 mg pill then smoke a few tokes of meth and hey MDMA roll is gone. Have seen it happen and been guilty myself. Had some MDMA that I got for some friends and they were all "fuck yeah I love ekkies" took the crystal and couldn't handle it so they smoked up some ice and gave me a toke. Lo and behold MDMA roll vanished and replaced by meth high. My advice take the MDMA and wait until your coming down and then take the speed. A lot of people did this when I was younger as speed was dirt cheap and MDMA expensive as hell. Also your going to have a shattering come down if you do this.
 
Why bother with MDMA when your speeding off your face? Also why PCP? In a pill more likely DXM IMO. PCP will destroy an MDMA roll, I mean it can overpower a fucking meth high and I know this from personal experience even 3 meo pcp will cut through a meth high. Both PCP and 3 meo pcp are NMDA receptor antagonists are a class of anesthetics that work to antagonize, or inhibit the action of, the N-Methyl-D-aspartate receptor (NMDAR). "The regional variation in PCP-induced DA release would be due to the combination of NMDA (N-methyl-D-aspartate) receptor blocking and DA reuptake inhibition by the drug." Nishijima K et al. Differential effects of phencyclidine and methamphetamine on dopamine metabolism in rat frontal cortex and striatum as revealed by in vivo dialysis. Synapse. 1996 Apr;22(4):304-12. Also 3 meo pcp and pcp are quite stimulating vs say K, MXE etc and are powerful drugs that should be used in 5 mg dose of pcp and 10 mg doses for 3 meo pcp. They also have a long subjective half life you'l be coming down of the mdma and back to baseline before the pcp/3 meo pcp is finished with you. Combining these two substances especially if unaware of injesting pcp/3 meo pcp with other drugs can result in some very sketchy experiences.

3 meo pcp and pcp may still have you feeling lucid but you will do random shit because the drug is in control. One friend had 30 odd mg of 3 meo pcp and was lucid enough to realize standing at an open window facing into a busy city street frantically waving his arms as he attempted to remove the negative energy looked ridiculous but he was unable to stop himself. I've had a bad pcp experience and luckily I wasn't flattened by traffic I was that high and entitled I thought traffic moving at 80 km should stop for ME and if not I MUST ATTACK!!! Also went a few rounds with my fridge... Combined in low doses say 5-10 mg 3 meo pcp and 10-15 mg 2cb can be enjoyable but pcp/3 meo are unpredictable at best and at worst a face chomping frenzy (that's someone else's face not your own).

Be very careful with pcp 3 meo pcp, I know pcp is around in the US (usually through "open air markets" or whatever nice pc name ghetto block dealing has) I've seen it here in OZ but 3 meo pcp is very available world wide and I urge caution with this substance. It can be magical and wonderful if respected but disrespect and abuse it at your own peril.
 
it is amazing to me that so many people would feel the need to combine dopaminergics with MDMA. i've never felt nothing remotely close to a lack of energy when rolling, in fact i found MDMA gives the perfect amount of energy, in that i can do whatever you want but still feel tired and remember it's time to take a break from the dancefloor. And i have experience with meth and perscription stims due to ADHD, still get heaps of energy from the good pure crystals.

YMMV i guess.
 
Well thanks for the advice guys i think im not gonna do it. and stick to my XTC pill ! i'd still would love to know how come mixing mdma and speed will make the comedown way worse ?
 
Which stimulant to add?

Dose:
So I'm thinking of giving this combo a try in December 2013:
Dose 1: 5-10 mg Dextroamphetamine/Methamphetamine [strictly no more] + 90mg MDMA
Dose 2: 50mg MDMA

My Life Story:
Let me tell you why I am interested in this combo. I first took ecstasy at raves in 2011. As I was new to the scene I took pills which I thought were 'only' MDMA and I did not test any of my gear at all. While rolling I always felt very energetic and wanting to dance. I also felt talkative and generally loved up.

One day in 2012 I got my hands on some MDMA powder (I took 200mg spread over 100mg doses). Up until this point I probably rolled 3-4 times per year on pills and I took a 3 month break prior to this roll thinking this would do the same job but it didn't (This was my 7th time rolling in 2 years). I still felt relaxed euphoric and loved up.. but it did not feel anywhere near the same chargy and 'wanting to dance' feeling I felt on those pills. Something was missing. Now that I have done more research I have a theory all the pills I took had some sort of stimulant added but I can't narrow it down to which one. It would be either methamphetamine, dextroamphetamine or caffeine.

I also noticed like many have mentioned in this thread, the comedown is worse when you mix stimulants with MDMA compared to taking MDMA alone. Well you're 100% right because coming off pills I always felt like a mix of something needing to get out of my system. Coming off the MDMA powder was much more relaxing, perhaps it was less neurotoxic? Just you know I have never taken any amphetamines on their own before.

TLDR; My questions
I would like to know if anyone has tried mixing different stimulants with MDMA on separate occasions?
Could you compare mixing either methamphetamine or dextroamphetamine with MDMA and explain in detail how these experiences differ?
What do you think of the dose I described? Will it give me that feeling I want?

-To give you my background: I take MDMA 4-5 times per year. This will be my 14th taking MDMA since 2011. My last roll was in June 2013 and I haven't 'lost the magic' yet.
-I still have a spare 400mg of MDMA powder I took in 2012, tested with a kit. I intend on using this.
-Thank you for reading this.. I will definitely let you know how the outcome goes Bluelight.
 
folley said:
plain amphetamine is one thing, but vyvanse is a tweaky, twitchy drug. Just gross. It would ruin the roll IMO
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YMMV; I, for one, find vyvanse smooth and euphoric. I would be more concerned with monoaminergic depletion (maybe just tachyphylaxis of other origins) by the time the roll kicks in). And you're obviously right: vyvanse != dexedrine, sort of like codeine != morphine (well, codeine has SOME intrinsic activity).

SE said:
when the MDMA wears off you won't be able to sleep
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Also, toward the end of the MDMA experience, you have 'reversed' 5ht transporters lacking stores of vesicular 5ht to release, inducing uptake of toxic metabolites. When additional dopamine is released, such toxic metabolites further proliferate.

ebola
 
Going to a rave in a few weeks and got some nice mdma to take with me however I'm looking on getting some phet as well for that extra kick. I'm only gonna have small dabs of it thru the night and see how it goes. Does it compliment mdma nicely in this sort of setting? I have used mdma and phet loads of times on there own but never combined the 2.

I will be taking a small amount about 2 hours before I have the mdma will this effect the mdma buzz and will I feel the come up as much?

I will be taking 150mg of mdma and just small dabs of the speed. They are both of high quality. I don't take any prescription amphetamines or antidepressants I'm just a casual drug user and don't have any addictions etc and I'm aware of the dangers of mixing but I'm experienced enough to know my limits.
 
meloen1 said:
This is the second combination subthread, this time for Stimulant type drugs such as amphetamine and MDMA.


Methamphetamine, amphetamine sulphate, Adderall (a dextroamphetamine saccharate, dextroamphetamine sulfate, racemic amphetamine aspartate monohydrate, and racemic amphetamine sulfate mix), Dexedrine (Dextroamphetamine sulphate) and other classic amphetamines will be the main discussion because they are the most tested and are "safer", but RC stimulants such as 4-FA, MPA, MDPV, a-PVP and other new chemicals may be discussed as well.

Be warned however, as these new RCs are untested and often contain adulterants. You take it upon yourself to look up all interactions before hand and always take extreme caution when combining unresearched drugs.



Cocaine and MDMA could also be discussed, but due to it's unique interaction with MDMA it may deserve it's own thread. Methylphenidate has the same interaction, as does any other dopamine/serotonin/norepinephrine re-uptake inhibitor.





Combining MDMA with amphetamine has been shown to be GREATLY more neurotoxic than taking MDMA or meth/amphet alone, as a large amount of MDMA induced damage to the brain is caused my dopamine related free radicals in the brain entering and destroying serotonin axons/dendrites


Showing that MDMA damage is caused by oxidative stress and free radicals:


Showing that Meth (other amphetamines are extremely similar) also causes this same damage:



Using common sense, we can infer that the two together is going to be MUCH harder on the brain and body than either drug alone. That is shown here:







So, it's a DAMN neurotoxic combo. But there is a reason why it is so bad for you... it feels DAMN good! I'd be lying if I didn't say I didn't really used to like this combo... but it caused an untold amount of damage to my brain and I don't think I'll ever touch it again.


If you do decide to use this combo, dose slightly lower than your normal MDMA dose (say 120mg instead of 150mg) and dose VERY low on the speed. I would never go over 25mg of amphetamine and 15mg of methamphetamine... less is more with this combo. Speed is a very strong drug, and even small amounts will give you the energy you're looking for.





Good luck and happy tweaking ;) Post any experiences and questions here!












OP's original post: First few times I did MDMA I had these intense energetic rolls, where you feel weightless. These have never come back. Although still rolling very nicely, I don''t have that massive energy rush anymore. I often see people stating that taking amphetamine with MDMA reduces the empathy and magic. I like the empathy, but the extreme empathy and hugging is nice, but I would trade some of the empathy for more of a rushlike roll during a rave. So was thinking adding 5-10mg of amphetamine to a cap with 130mg MDMA crystal. What effect does this have on the roll. Will such a low dose of amp still remove all the empathy magic?
Or will it be more euphoric with such a low dose of amp and give a great rush?

I know neurotoxicity is increased, however I think such a small amount of amp will not greatly increase neurotoxicity, as long as you take your 1000mg of vitamin C 5 hours into the roll.
What are you ideas on a roll with amp (a LOW dose, so no high doses), compared to a roll without amp during a rave. Wich is better.
And does a little bit (5mg or 10 at most) greatly increase the hangover?
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For me the nest mix os speed putty n e's coz the base makes the e's buzz much longer n more intense.....n dunno bout others but if im up on MDMA n have line of coke it starts to bring me ryt down from da e buzz :( really pisses me off!!!!!!!!!!!!!!!!!! Just levelin out from a r88 hard md role from mid afternoon 2day and been bumpin MKat since 6pmish n its a nice mix tbh.........surpirsed the hell oout of me but be safe and mixin drugs is not adviseable in any circumstance coz dangers increase!!!!!!!!!!!!!!! stay safe and happy ravin :)
 
take the speed first and wait couple hours b4 takin the roll.....and wen the roll kicks in it will xtend the e buzz by a good few hours.......but u will av a really rubbish comedown after ......take as lil speed as poss for less comedown effects......coz md on its own causes no rteal cumdown but base alone dus and mix e wiv it n the cumdown can b very savage speakin from many years experience mixin speed and e 2gether most weekends for 14 years!!!!!!!!!!!!! stay safe everything in moderation and happy ravin :)
 
The Sulphate/MDMA combo is one I thought was so common, it didn't bare a mention.

I mix a primary stimulant with most entactogens/empathogens - the lovey-dovey, uninhibited gates of conversation may be open; but I wanna tweak/speak every thought at that point.
Though MDMA itself is a rarity in my use - can be years between experiences.
Thus; the novelty it brings to social situations is one I want to make the absolute most of.

Though I would never mix 'Phet with my beloved Evey. The tranquillity of MDE(A) is too perfect to ruin.
 
Is it worth smoking some meth and doing mdma/mda? What effects tend to happen?
 
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