Codeine Admin Methods...

[Dynamic_Coins]

Hey all, its been a while...looking for some advice on codeine doses. I'm sitting on a bottle of 30mg tabs (pure, no APAP). I've tried it once so far but wasn't particularly impressed with the results. This was the first opiate experience i've had so i'm not used to the buzz, but at peak I felt little more than a mild calm.
A couple hours after eating I took 90mg, 30 min later another 120, and another 30 min later maybe 60 mg more.
Any ideas as to what I should try next? Is oral the best means of administration or is it feasable to rail? Thanks...

 

[Grand Master of Somniferon]

Originally posted by Dynamic_Coins:
Hey all, its been a while...looking for some advice on codeine doses. I'm sitting on a bottle of 30mg tabs (pure, no APAP). I've tried it once so far but wasn't particularly impressed with the results. This was the first opiate experience i've had so i'm not used to the buzz, but at peak I felt little more than a mild calm.
A couple hours after eating I took 90mg, 30 min later another 120, and another 30 min later maybe 60 mg more.
Any ideas as to what I should try next? Is oral the best means of administration or is it feasable to rail? Thanks...
Some schools of thought say that it is best to take it all at once, as the enzyme resposnible for the demethylization of codiene into morphine is also inhibitited by codiene, so after the initial dose, it is pointless to take more for about 4 hours or so. The moral of this story is that you should take the entire dose at once, start with 120 mg, and don't redose for at least 3 hours. Also, stick with oral, unless you wanna stick a turkey baster up your ass.

 

[zorn]

Don't snort those guys... it works but they will clog up your nostrils for a while. Unpleasant, and you don't get much more out of it.
It takes me about 300mg of codeine for optimum effects, with no tolerance... I would try hitting this all at once, on a relatively empty stomach. Also most opioids improve after a few uses, I've found. You might try just relaxing when you're on it -- I find that the effects from any opioid get dramatically stronger if I just let them wash over me, as opposed to if I'm concentrating on doing something else.
However around 5-10% of the population is very resistant to codeine, you might be one of these unlucky folk.

 

[fairnymph]

Some schools of thought say that it is best to take it all at once, as the enzyme resposnible for the demethylization of codiene into morphine is also inhibitited by codiene, so after the initial dose, it is pointless to take more for about 4 hours or so.
This is absolutely spot-on. It is even true that if you are taking codiene for its analgesic (pain-relieving) properties, you should take alot of codeine right away, when you first start feeling the pain. If you wait until the pain is bad, and THEN try to retroactively make up for it by taking more codeine, it is not nearly as effective at covering the pain.
As for zorn's suggestion that you take it on an empty stomach, I do NOT think this is wise. In fact, it is ALWAYS recommended that you take codeine with food and NOT on an empty stomach. MANY people's stomachs are very sensitive to opiates and find that they need a small amount of food and liquid in them to tolerate the codeine and avoid nausea and stomach pain. I suggest eating a plain, carb-based food like a peice of toast or some crackers. I myself do this and I take codeine regularly for pain. If you eat just a bit but not too much the codeine will still hit you plenty hard and your stomach will be happy as well.

 

[zorn]

^^^^ That's actually a good call.... I am mostly immune to opioid nausea and so I forget this. Taking it after a big meal can really slow things down, almost effectively halving the dose for me.

 

[fairnymph]

Oh, and DON'T snort or inject or smoke codeine...orally is really the ONLY way you can do codeine.

 

[Grand Master of Somniferon]

Originally posted by fairnymph:
Oh, and DON'T snort or inject or smoke codeine...orally is really the ONLY way you can do codeine.
You sure about that? I'll bet if you REALLY wanted to, you could mix it into a solution (saline possibly) and squirt it up yer bum. But, I can only see marginal benifits from this, and you would hafta hold in the solution long enough that it could get REALLY uncomfortable.