This fentanyl analog availability explosion is just crazy ridiculously out of hand especially being the second wave after the first one created analog act that's failing to do anything to keep this one from happening a and doing the damage they have been doing as it should.... It's outrageous as ours only successfully happening due to the attempts to curb opiate use by reducing the access to pharmaceutical opiates that have been around for the longest time a and have much less risk nearly none when a good doctor is making the effort to really make a good plan for a patient and educating them so they can have enough of an understand that with the opiates the patient can mask the problem of temporary physical pain until the proper non drug treatment methods that without the medication end up being unsuccessful due to the issues that the opiates mask, which prevent the patient from having the ability to maintain the non drug treatment that over time become fixed allowing patients to then tackle getting through likely possible withdrawals while maintaining the strength recovered that the treatment brought about so that one can continue life stronger thanks in part to the opiates that were used at a crucial period to help the patient overcome the pain brought on by the challenges the moon drug treatment methods require that without the opiates the patient would be bound to fail and begin to degrade even further than when they started treatment leading to disability that could've easily been avoided. Then there are those with chronic pain that can never recover to a point to where without medication it is bearable although one can manage with opiates if one understands the proper t regimen of opiates that can be stabiliy used at the same dose without ever fluctuating as to not cause tolerance change leading to times when the regular dose is not effective at all with a regimen such as hydrocodone or oxycodone sustained released for either form as daytime active pain maintenance meds due to their effect that prevents the narcotic sedation from developing as strong (at least in my experience) and using preferably the metabolite morphine based counterpart although any of either morphine, hydromorphone, oxymorphone, and even heroin if it was available everywhere while it's availability as prescribed is limited as an immediate release formulation for breakthrough pain as IMO the mu binding opiates while more likely to cause heavy narcotic/sleep inducing sedation gives the best pain relief provided with a reduction of tightness and tension no other pain med has been able to provide I have found in my experience especially without a lack of size effects that cause any relief provided to become pointless while the opiates that opiates that have more activity focused on the kappa region like hydro/oxycodone creating mu effect by converting to their morphine counterpart while each become more selective to either the my for morphine counterparts and kappa for codeine counterparts as the molecule becomes smaller and smaller as they go from no prefix to hydro then oxy while I believe the best and perfect combo that sustains relief without side effects or even cognition impairment besides the physical dependency is using oxycodone in its 12 hour sustained released form orally 2-4x a day depending on daily and individuals needs while oxymorphone is used as needed 4x-6x by either oral/nasal/IV depending on an individual's preference needs as with a half life of 7-9 hours it is the one opiate of all the opiates that are morphine and codeine base and have basic receptor activity vs extensive in areas other than the opiate region that like oxymorphone have a long enough half life that with immediate release forms the medications they don't leave one withdrawing so quickly after a dose that it prevents the necessary full eight hours rest needed to maintain good health that without a sustained release form oxycodone, hydrocodone, hydromorphone, morphine, heroin, and codeine one could not obtain while dependant as the maximum half life of any of these is four hours.....
Just to not be too off topic with my rant I'll tie it up pointing out that due to fentanyls build as a key to fit as deeply into the opiate receptors and create as powerful an effect with the s smallest amount possible even if it leaves it falling apart so fast that it only has a half hour half life maybe hour at best causing it to be pretty useless for managing pain except in extremely short term yet excruciatingly painful situations such as surgery and woman in labor where as soon as the ultra short term pain ends it will leave the system near immediately and something like hydromorphone that has a very short half life as well can be used to ease out of the ultra powerful fentanyl. Even though it's developed as sublingual and nasal for breakthrough and patches for long term pain I highly doubt anyone really would need it where other basic opiates would handle most pains as long as one found a good dose and maintained minimal dosing without taking doses so close together that they stack and increase the tolerance, but at the same time don't deny fentanyl possibly being the only choice that is strong enough for such severe pain. It just has such a high likelihood of causing an out of control tolerance increase it should be the last resort choice always. The most dangerous thing about this compound is that without any modification it can absorb through the skin so it really needs to be properly formulated and used as it should as oddly the transdermal ROA has highest bioavailability next to IV and requires the lowest dose to cause effect making it extremely dangerous to be around the raw pure powder form of this compound and likely ask of its analogs as well.
To end my rant and ideology no one should attempt self medicating with fentanyl due to it being the riskiest of any opiate due to its unique nature that leads to dosing required so often it disrupts any life and leaves no possibility for a full night's sleep. If anyone does choose to foolishly choose to become a gunnie pig for this fentanyl analog or any even knowing everything I shared above start with the lowest dose as if it was more potent that fentanyl.... learn volumetric dosing... Only handle without exposed skin anywhere and a mask to prevent inhalation as well as working over a removable easy to clean surface to prevent spills that if left and not cleaned can kill an innocent animal or even unfortunate person who might step on the spill barefoot.
I hope everyone stays safe although really the best thing to do is boycott these fent analogs even if they seem like an easy solution for a possible supply that can help maintain for all the reasons above as well as to make them a waste of money to the vendors who irresponsibility make this stuff available as they will not keep wasting effort to carry what doesn't sell. It's only available as sadly there is demand, which is in control of the buyers not the greedy vendors who only respond to demand even if it's not what is desired, but something that is obtained when desires aren't accessible whether or not it truly is a replacement or just something that seems like one only to turn out to be worse than nothing most fentanyl users find out once dependant.
I know my writing is too much and weird, but my message is there, full of heart, and strong even if not that clear.
Just to not be too off topic with my rant I'll tie it up pointing out that due to fentanyls build as a key to fit as deeply into the opiate receptors and create as powerful an effect with the s smallest amount possible even if it leaves it falling apart so fast that it only has a half hour half life maybe hour at best causing it to be pretty useless for managing pain except in extremely short term yet excruciatingly painful situations such as surgery and woman in labor where as soon as the ultra short term pain ends it will leave the system near immediately and something like hydromorphone that has a very short half life as well can be used to ease out of the ultra powerful fentanyl. Even though it's developed as sublingual and nasal for breakthrough and patches for long term pain I highly doubt anyone really would need it where other basic opiates would handle most pains as long as one found a good dose and maintained minimal dosing without taking doses so close together that they stack and increase the tolerance, but at the same time don't deny fentanyl possibly being the only choice that is strong enough for such severe pain. It just has such a high likelihood of causing an out of control tolerance increase it should be the last resort choice always. The most dangerous thing about this compound is that without any modification it can absorb through the skin so it really needs to be properly formulated and used as it should as oddly the transdermal ROA has highest bioavailability next to IV and requires the lowest dose to cause effect making it extremely dangerous to be around the raw pure powder form of this compound and likely ask of its analogs as well.
To end my rant and ideology no one should attempt self medicating with fentanyl due to it being the riskiest of any opiate due to its unique nature that leads to dosing required so often it disrupts any life and leaves no possibility for a full night's sleep. If anyone does choose to foolishly choose to become a gunnie pig for this fentanyl analog or any even knowing everything I shared above start with the lowest dose as if it was more potent that fentanyl.... learn volumetric dosing... Only handle without exposed skin anywhere and a mask to prevent inhalation as well as working over a removable easy to clean surface to prevent spills that if left and not cleaned can kill an innocent animal or even unfortunate person who might step on the spill barefoot.
I hope everyone stays safe although really the best thing to do is boycott these fent analogs even if they seem like an easy solution for a possible supply that can help maintain for all the reasons above as well as to make them a waste of money to the vendors who irresponsibility make this stuff available as they will not keep wasting effort to carry what doesn't sell. It's only available as sadly there is demand, which is in control of the buyers not the greedy vendors who only respond to demand even if it's not what is desired, but something that is obtained when desires aren't accessible whether or not it truly is a replacement or just something that seems like one only to turn out to be worse than nothing most fentanyl users find out once dependant.
I know my writing is too much and weird, but my message is there, full of heart, and strong even if not that clear.
