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cocaethylene -not experienced - fun but unexpectedly strong

NikkiNumberNine

Bluelighter
Joined
Jun 18, 2006
Messages
505
Location
Seattle
My drug background: I'm normally a stim-loving girl - meth and adderall - and I sometimes do coke, although overall I'm underwhelmed by it. I mean, it's nice, but just nice, not awesome. And It doesn't fuck me up seriously, just buzzes me a bit.

And I actually very rarely drink alcohol, because I don't care for depressants even as mild as that. So when I say rarely I mean, oh, twice a year. And even then, I don't get shit-faced puking drunk, although it doesn't take much to get me tipsy. A couple glasses of wine will leave me markedly less inhibited in my manner and conversation and somewhat impaired in my fine motor skills. My friends tell me I'm cute, although I think my being cute when I'm drunk is probably as much about the rarity of it as anything. I myself tend to find drunk people unattractive.

But I was at a big party Saturday night, and my host had informed me, before the event, that he had some really good champagne that he'd gotten just for me, because he knows I like good champagne. (Cheap champagne is terrible.)

And there was also some coke, for a few select people. Now I read right here on BlueLight that doing coke and alcohol creates a whole new chemical in your body, cocaethylene, and that piqued my curiosity. I would have thought that a depressant and a stimulant would just work against each other, so I wouldn't have thought to do both in one evening.

So I decided to see what that was like. I did two lines of coke, probably 1.5 inches in length and neither really fat nor really skinny, and drank a fairly large glass of wine, within about a fifteen minute period. (The coke went pretty fast, but the wine was too good to gulp.) I got up and walked around the party and within a few minutes realized, wow, I am pretty fucked up here, definitely more so that either the coke or the champagne alone would account for.

It wasn't like being drunk, exactly. I wasn't unsteady when I walked, like I often am when I drink. (Especially when I'm wearing high heels.) My lips did not get numb, which also often happens when I drink. My eye-hand coordination seemed fine.

Nor was it like a speedy coke-buzz. I did not feel up. I felt a little dissociated, if anything. You know that looking at the world through a distortion lens feeling? Yeah.

I was extremely uninhibited in my manner and conversation, though. You know all those things you know about people, but do not say aloud, because it would be rude? I said several of them, and I only stopped myself with GREAT difficulty from saying more. Whoops. I'm normally a pretty polite person, too. (Luckily no one seem inclined to take serious offense, probably because they'd been drinking too.)

About an hour later, I'd had another glass of wine, and was invited to do some more coke, so I did, two more lines. Oh wow, now I'm really fucked up. Again, no major loss in the walking/talking/putting on lipstick correctly department, but serious distortion lens/uninhibited feeling. And I could definitely not track any complex conversations or handle any kind of crisis that involved a fast response.

(Ladies in particular, be careful with this. I was among trusted friends and no one was trying to get in my pants who shouldn't have been there, but I bet I would have been fairly vulnerable to a predatory type of guy.)

I wasn't euphoric, though, my mood didn't change noticeably. I was in a good mood when I started and I stayed in a good mood, but it wasn't like speed that way.

And damn, it lasted a long time! Coke always wears off fast and usually alcohol, while it affects me quickly, doesn't last very long on me either. If I stop drinking, within an hour I usually feel relatively sober, even though I might not be legally.

But after the second round of coke + wine, the voice in back of my head said, "You should stop now. Or bad things will happen." I always listen to that voice, so I declined any more of anything. But still, I stayed fucked up for several hours after that. It had tapered off somewhat when I went to bed, but I was still feeling impaired, and I woke up after about six hours and thought, damn, I'm still sort of buzzed. I did not have any noticeable comedown/hangover, though.

I admit I'm not sure if I had 3 or 4 glasses of wine, but I know that I only did four lines of coke, and I was way more trashed than either one of those alone would explain. Way. I would advise caution in doing this, because even if you have a high tolerance for either coke or alcohol alone, the combination seems to be way more than the sum of the parts.

Cocaethylene: not something I'd do every day, but an interesting non-stim experience.
 
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yeah i love to mix my coke and alcohol all the time. I love the way it makes me feel, the high you get from coke but none of the anxiety or cravings I get after using.
LOVE LOVE LOVE
it's such a great feeling, reading this post makes me want to do it right now.
Damn I have to wait til tomarrow though because im on X (2 red louis vuttons) right now.
Good trip report though!
 
i was playing beer pong one night.. me and uberdank were winning a few games.. he pulled to aside when another games was goin on that we weren't play and suggestd i go a rail.. i was kinda drunk at the time.. so i did, instantly felt not drunk anymore and really happy..

Yo and booze is ok, but i still hate YO :X
 
isn't cocaethylene an impurity, i remember reading somewere that its one of the few impuritys left when makeing pharmecuetical grade cocaine, don't remember exactly, and ive never heard that mixing alcohol and cocaine does this, kinda cool tho i guess if it does
 
An overview of cocaethylene, an alcohol-derived, psychoactive, cocaine metabolite
by MJ Landry

Cocaethylene is a psychoactive ethyl homologue of cocaine, and is formed exclusively during the coadministration of cocaine and alcohol. Not a natural alkaloid of the coca leaf, cocaethylene can be identified in the urine, blood, hair, and neurological and liver tissue samples of individuals who have consumed both cocaine and alcohol. With a pharmacologic profile similar to cocaine, it can block the dopamine transporter on dopaminergic presynaptic nerve terminals in the brain. It increases dopamine synaptic content, provoking enhanced postsynaptic receptor stimulation, resulting in euphoria, reinforcement, and self-administration. Equipotent to cocaine with regard to dopamine transporter affinity, cocaethylene appears to be far less potent than cocaine with regard to serotonin transporter binding. Lacking the serotonergic-related inhibitory mechanism, cocaethylene appears to be more euphorigenic and rewarding than cocaine. Synthesized and administered cocaethylene has a behavioral stimulation profile similar to cocaine. Cocaethylene has been shown to be less potent and equipotent to cocaine, and alcohol plus cocaine produces more stimulatory locomotor behavior in mice than either drug alone. Equipotent to cocaine with regard to primate reinforcement and self-administration, cocaethylene can substitute for cocaine in drug discrimination studies, and can produce stimulation of operant conditioning in rats. With regard to lethality, cocaethylene has been shown to be more potent than cocaine in mice and rats. The combination of cocaine and alcohol appears to exert more cardiovascular toxicity than either drug alone in humans. Alcohol appears to potentiate cocaine hepatotoxicity in both humans and mice.
 
^^It doesn't... it just does with some stuff. Pure pharmaceutical heroin, even injected cleanly, does very little if any brain or organ damage, for example. And psychedelics are extraordinarily safe substances.

But yeah, alcohol is very toxic even by itself compared to most drugs, and cocaine mixed in is even worse. Fun sometimes, but bad. Bad!
 
I really enjoy dosing up on either coke or meth after I'm trashed on booze. I lose the urge to drink if I do the stimulant first.

And, since this is a harm reduction board...be advised that this is a very unhealthy thing to do. Rough on the heart.
 
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