N&PD Moderators: Skorpio
coca and mephedrone
Is it possible that the chewing of coca and sodium bicarbonate prior or during mephedrone usage could mitigate some of the negative circulatory problems of meph. I understand coke reduces blood presure and has a calming effect whilst still being a stimulant.
Could anyone definitely indicate againnst the combo, coca leaf is not cocaine.
any major dude
Bluelight Crew
well cocaine, present in coca leaf, is also a vasoconstrictor, so it would likely only worsen things
and...
Absinthium, worm wood, is a cardiac stimulant to improve bloodcirculation.Black indian hemp is also a cardiac stimulant, and possiblevasodialator.Marijuana is a vasodialator.Angelica Root, Dong Quai is a vasodialator.....
seusemgoose
Greenlighter
Damiana son
Phener
Bluelighter
no but it does contain cocaine. Considering cocaine is cardiotoxic + mephedrone is also potentially cardiotoxic - not really a wise harm reduction type combination. Agreed the cocaine in coca leaf is negligible anyway.
These kind of combinations are pointless in view of a potential reduction in toxicity / harm reduction. Just going to make things MORE complicated.
If your going to take mephedrone - just face facts - it will still potentially be toxic on some level (as we all know toxicity unknown/speculative with research chemicals)
any major dude
Bluelight Crew
To negate the vasoconstrictive properties of mephedrone, one could smoke pot & opium (papaverine is also a vasodilator). Alcohol also has blood thinning properties which might somewhat mitigate, in the very short term, vasoconstriction.
So do meph, drink, then smoke some grass with a bit of opium on top. At the very least you won't particularly care about the vasoconstriction by the time you're done.
Or just don't do meph 
adder
Bluelighter
It's not a very good idea to advise mixing blood thickening drug with a vasoconstrictor. Especially if you're planning to use ethanol that once in the system does hell of a lot of things.
I'll just go with this:
any major dude said:
Yes, you don't like this how-the-heck-fucked-up-I-can-get-using-it drug - just don't do it. It's that simple.
any major dude
Bluelight Crew
the above advice was in jest... sort of also, did you mean blood thinner?
And there's been very no human studies of mephedrone, so god only knows how alcohol effects its metabolism. I suppose its possible that there could be some type of cocaethylene-esque by product. By that I meant simply different metabolite when co-administered with ethanol, not something terribly chemically similar to cocaethylene