Chlormethiazole can be used safely enough at home, just as long as it is treated with the due respect. Capsules are 192mg each, and intended to be used in replacement of, not along with the booze, just keep in mind to never mix it with depressants. I do take it alongside opioids, but only in clinical doses for seizure control, and I've been opioid tolerant longterm. Even then, it packs a fuck of a punch. Bugger about with it stupidly or carelessly and the above poster's warnings about it showing no tolerance for fuckabouts, is true. But it does do what its meant to do when used as such, and unlike benzos, you get somewhat of an indication of when its going to start taking effect, at least with the capsules, or with the freebase orally, I've never taken the edisylate syrup, no idea what thats like, other than as a general idea of the effects of the drug, its a bugger to salt.
The onset is extremely rapid, once the capsules break, or if you can manage to get past the funky taste and stick the base in some cold drink (nonalcoholic, I mean), kinda how oral ether is used, and toss it back. Stuff hits about as fast IMO as a dose of spirit liquor, in terms of time until onset, minutes from when its actually released if its in capsule form, so its somewhat easier than with benzos to feel one's way to the ideal dose (which should, if using for a taper, stop at the minimum dose required to hold one, and dosing go down slowly over a week or just over, if that isn't too fast.)
Be aware, if tolerance to the other GABAergic was high, that there is one rather unfortunate side effect, that appears to be cumulative over short, sustained high dose intake, and that is most probably a facet of sulfur chemistry all too frequent. What do most people associate with fire and brimstone? well it smells worse than anything they are likely to have 'down there'. Like the devil himself sharted, decided it was too much pollution to add to hell, and had it piped into a donald trump speech, it really is quite foul. And it STINKS, whatever this metabolite is, and it will come out in everything. Its like the sulfur equivalent of tellurium breath, well, at least what I've read about the latter. Never had the experience and never want to, but whatever it is, A-smells bad enough to send people turning and running from 100 meters off in open outside air, and B-will follow you to the ends of the earth, coming out in saliva, piss, sweat, nasal fluid (just where you want something mercaptan-esque to make a nest for the next week or so), and leave traces on most anything you touch that can't be wiped down with bleach or in the case of glassware fouled by overheating the stuff, given a chromic acid bath. Whatever it is, it doesn't show with low dose continual (in my case, 192mg 3xdaily, for years, used for seizure control) use. But if used say, for a high dose taper, or really hit hard recreationally, oh damn, that stink is like the devil's own ghost when it comes out to haunt you. I reckon the only way to get rid of it, bar burying a body in a lake, would be to kill the host and burn the remains.