Chemically, why doesn't cannabis cause some physical addictions?

[Elven Warriorr]

What does cannabis's chemical composition not have, that tobacco, alcohol, heroin, crystal meth, and cocaine DOES have, which causes those physical addictions to happen?

 

[FnX]

What does cannabis's chemical composition not have, that tobacco, alcohol, heroin, crystal meth, and cocaine DOES have, which causes those physical addictions to happen?

What makes you so convinced that cannabis doesn't cause physical addiction to any degree? If you make some kind of distinctions between physical and mental addictions, could you clarify what exactly physical addiction means to you? This issue has been covered in a multitude of threads in CD already though so I would really recommend using the search engine, might find your answers more efficiently that way.

 

[RobotRipping]

physical addiction is dependence. Cannabis has been well documented to cause physical dependence in chronic users. The withdrawal effects include night sweats, anxiety, irritability, loss of appetite, intense dreams and other minor issues.

Why doesn't it cause a dependence compared to tobacco, alcohol, heroin, methamphetamine or cocaine? well most of those don't cause a huge dependence but rather create more of an addiction. For heroin, alcohol and a bit for methamphetamine and cocaine it has due to with the neurotransmitters released and how the brain responds to it, either by creating too many new receptors in the brain or rewiring the brain causing reinforcing behavior and cravings.

For opiates, your body stops creating as many endongenous opioids and creates more opiate receptors so that when you don't have your normal amount of opiates in your body, you will withdrawal as all those receptors scream out to be bound to and there's nothing there. Alcohol/benzos works similarly. Tobacco, methamphetamine and cocaine are extremely reinforcing drugs (due to dopamine most likely), rewiring the brain to seek out that dopamine flood or rush.

in terms of dependence, opiates are just much much stronger than cannabis, as well is alcohol and bind to parts of the brain that become deeply affected after years of use and it takes a very long time for the brain to return to homeostasis, the cannabinoid system is a bit more forgiving and dopamine release is little in comparison.

anything can be addictive, including bluelight, cheeseburgers, or whatever else. Cannabis can be addictive for some people but for the most part, cannabis is self limiting and people control themselves with cannabis quite well. Addiction being, using a drug despite negative consequences in your life. Cannabis does not create a strong reinforcing behavior (via dopamine) that is seen with methamphetamine/cocaine for example, according to brain imaging studies.

Cannabis does not create a strong physical dependence as it is not completely changing the brain like benzos or opiates do. If you can find a super strong cb1,2 agonist, you may be able to have a massive withdrawal from that but as cannabis stands as a plant, there's not much potential for true addiction or much of a dependence. THC is only a partial agonist and the rest of the cannabinoids help to either prevent massive tolerance build up or addictive behaviors, for whatever reasons, they just don't bind to the cb1,cb2 or other receptors hard enough to cause any real issue.

sorry if some of this doesn't make sense.

 

[Elven Warriorr]

physical addiction is dependence. Cannabis has been well documented to cause physical dependence in chronic users. The withdrawal effects include night sweats, anxiety, irritability, loss of appetite, intense dreams and other minor issues.

Why doesn't it cause a dependence compared to tobacco, alcohol, heroin, methamphetamine or cocaine? well most of those don't cause a huge dependence but rather create more of an addiction. For heroin, alcohol and a bit for methamphetamine and cocaine it has due to with the neurotransmitters released and how the brain responds to it, either by creating too many new receptors in the brain or rewiring the brain causing reinforcing behavior and cravings.

For opiates, your body stops creating as many endongenous opioids and creates more opiate receptors so that when you don't have your normal amount of opiates in your body, you will withdrawal as all those receptors scream out to be bound to and there's nothing there. Alcohol/benzos works similarly. Tobacco, methamphetamine and cocaine are extremely reinforcing drugs (due to dopamine most likely), rewiring the brain to seek out that dopamine flood or rush.

in terms of dependence, opiates are just much much stronger than cannabis, as well is alcohol and bind to parts of the brain that become deeply affected after years of use and it takes a very long time for the brain to return to homeostasis, the cannabinoid system is a bit more forgiving and dopamine release is little in comparison.

anything can be addictive, including bluelight, cheeseburgers, or whatever else. Cannabis can be addictive for some people but for the most part, cannabis is self limiting and people control themselves with cannabis quite well. Addiction being, using a drug despite negative consequences in your life. Cannabis does not create a strong reinforcing behavior (via dopamine) that is seen with methamphetamine/cocaine for example, according to brain imaging studies.

Cannabis does not create a strong physical dependence as it is not completely changing the brain like benzos or opiates do. If you can find a super strong cb1,2 agonist, you may be able to have a massive withdrawal from that but as cannabis stands as a plant, there's not much potential for true addiction or much of a dependence. THC is only a partial agonist and the rest of the cannabinoids help to either prevent massive tolerance build up or addictive behaviors, for whatever reasons, they just don't bind to the cb1,cb2 or other receptors hard enough to cause any real issue.

sorry if some of this doesn't make sense.

Cocaine releases dopamine to 350 units, and meth releases dopamine to over 1000 units.

How many units of dopamine does cannabis release?

 

[Jibult]

Why doesn't it cause a dependence compared to tobacco, alcohol, heroin, methamphetamine or cocaine? well most of those don't cause a huge dependence but rather create more of an addiction.

Dude.

The withdrawals from all five of those substances are terrible. Crazy addictive substances that also can create crippling dependencies.



I'm thinking you typoed or misedited somewhere but I don't really know... Everything else seemed on point.

 

[NeighborhoodThreat]

You asked nearly the exact same question in this thread here. Stop posting the same threads (or very similar threads) over and over again.

Just because you didn't get the answer you wanted in your other thread doesn't give you the right to start another one on the same topic. It clutters up the board.