weekend addiction
Bluelighter
Would using both of these to potentiate clonazepam have any benefit? Any dangers involved?
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Pill2Chill
Bluelight Crew
No dangers. Tagamet is the stronger inhibitor of the two so I don't think there's much point in using both. Though it definitely can't hurt.
The reason Tagamet potentiates (some) benzos is because it's a CYP450 liver enzyme inhibitor, the enzyme that metabolizes clonazepam (and a few other benzos). If you use an inhibitor the enzyme will get 'clogged', which forces more unmetabolized clonazepam to remain active in your system, causing a stronger effect. It'll also take longer for your body to get the clonazepam out of your system as it needs to be metabolized first.
The reason Tagamet potentiates (some) benzos is because it's a CYP450 liver enzyme inhibitor, the enzyme that metabolizes clonazepam (and a few other benzos). If you use an inhibitor the enzyme will get 'clogged', which forces more unmetabolized clonazepam to remain active in your system, causing a stronger effect. It'll also take longer for your body to get the clonazepam out of your system as it needs to be metabolized first.
Psychedelic Jay
Bluelighter
Hell, throw it in a blender... LOL
It's fine as long as you don't put any other drugs on top of it you have no tolerance for.
It's fine as long as you don't put any other drugs on top of it you have no tolerance for.