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capped mdma

Just eat it. I tried gumming it and letting it dissolve (even on an empty stomach) and i find that shit just dont work as potently. I snorted it once (after crushin up all them fuckin crystals into a nice powder) n all that did was clog my nose up and burn. Didnt roll. Now what the fuck is up with that? Hahaha stubborn lil chemical
 
I'm gathering that many would prefer swallowing a capsule rather than sublingual administration, but just to be absolutely clear: Is there anybody who would say that
a.) they've had a noticeably better high when letting MDMA dissolve in the mouth vs. swallowing it
b.) they would prefer taking it sublingually to swallowing it because it's worth it despite the horrible taste and/or burning sensation
 
that's a picture of one salmon. i'm talking about certain other salmon.

alasdair

Oh thats cool, I might be willing to accept that as a theory of yours if you provided enough evidence that they grew lungs and claws to be able to climb trees, similar to how I showed a link (that you hypocritically informed me was 100% wrong because "emotions are in the neurons" or some bull shit that is degrading the level of discussion on Bluelight due to having absolutely nothing to back it up) between the two sources of Serotonin, and I also proved how drugs that work on serotonin in the brain often cause changes to the chemicals in the stomach as well.

In addition to the subjective effects (also, I like how you say its MY opinion that snorted MDMA is less loved up, when I didnt even notice this until I read threads about it on here), there is plenty of evidence to say that bombed MDMA is more serotonergic


So really, I have everything I need to support my argument already. It may be a bit spread out and I dont use the best of words, but for you to come here and shoot me down over the fact that I said "MDMA works on serotonin", which it does, when I was TRYING to be vague and explain this to you in as little words as possible, is about as childish as you say Ive been.


You insisted I was wrong from the beginning, probably without understanding what I was even talking about, and now your stubborn ass has to keep trying to drag me down and prove that Im wrong.

You originally did this by saying my facts were wrong, then you went to calling me stupid after I disproved you, now you've switched it up and you're exaggerating things to keep people from the point of what Ive been trying to get across.



But Im not going down that easily. When provided with evidence, it is the rebutting parties job to provide an argument or fact that disproves the theory... I have yet to see anything that disproves this, only evidence supporting it.


Wheres your evidence for your new Salmon?
 
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Mdma mimics certain neurotransmitter in a certain area of the brain... doesnt matter how it gets there, all that matters is how much... experienced users know that snorting is not a very effective method compared to eating it... and it tastes so horrible most never got far woth sublingual lol... my guess is that sublingual would be similar to insuffilated as far as how much is absorbed thru... but you swallow the rest anyway so it all still gets absorbed anyway... part under the tongue and the rest in he digestive tract...

Mdma has been around quite a while and people have tried every roa possible.... if there was some way that worked better than eating it then it would be very popular by now...
 
Exactly, if injecting is the best RoA, then why dont people do that often? Simply put, its because eating it feels better.

But CI, you say that it doesnt matter how it gets there, but how much. I wouldnt really agree with that. Take 2C-x, snorting is much more effective, but the trip is often quite different from oral.

Obviously snorted MDMA is still going to release serotonin, but its just not going to get anywhere near the response from the stomach that oral will
 
2c-x isnt mdma... ketamine works awesome snorting, so does blow but neither work nearly as well eaten.. apples and oranges... i just said mdma isnt that effective snorted...

When a drug gets absorbed that means it gets into the bloodstream and gets pumped everywhere... it doesnt matter wether it absorbs in your mouth, nose, stomach or even foot for that matter... the difference is that some drugs can be absorbed one place but not another... or not as well... some drugs absorb thru mucous membranes well while others dont... same with the stomach and intestines... same with skin... some drugs can be absorbed thru the skin (transdermal patches for example)...

But once they get into the bloodstream, the magic happens when they get into the brain
 
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Well thats because the BA% is much lower orally for both ketamine and cocaine...

Even when enough is taken of those drugs though, the high usually has differences in feeling than when its taken like its supposed to. Take meth as an example too, people often say smoking it is in its own class. If it was just the rush, people would say the same about injection, but you'll find a lot less people saying that.

Hell you might even be able to venture to say that all drugs have an RoA that works best for them, even if others have a higher bioavailability percentage
 
And the BAC for mdma is lower if you snort the same amount as eating... thats my whole point... its not where it goes in... its how much actually gets in... and that depends on 2 main things... dosage and ROA
 
Well but still if you snort less MDMA its still that speedy like high, if you snort more its the same thing, just more.. maybe I dont understand what you're saying?

You honestly don't know what you're talking about. I'm not gonna sit here and write out hundreds of words to explain why because it's clear that you've just refuted everybody else that has tried to do so.

But consider this. Snorting MDMA, or taking it sublingually, for example, provides a faster onset of the drug. Has it occurred to you that this fast onset, due to the higher bioavailabilty of these routes of administration, demonstrate a seemingly different effect that could somewhat be described as "speedier"?

Consider this analogy.. you're smoking a cigarette. You feel an instant spike of relief. Comapare this to say, wearing a nicotine patch.. you don't feel that same relaxed feeling as you do with smoking the tobacco. Yet you are consuming nicotine in both instances, AND HENCE STIMULATING THE NICOTINE RECEPTORS *IN THE BRAIN* however the way that you are consuming it alters the feeling associated with this physiological process.

The "less loved up" feeling you're talking about has absolutely nothing to do with whether serotonin is present within the stomach or not. It's got to do with the rate at which the drug enters the bloodstream and reaches the brain.
 
That kinda coincides withwhat im saying... different ROAs will produce different effects... but... the reason is not because its closer or farther from the brain, its not because its closer or farther to organs that produce or store neurotransmitters... its because different roas have different rates and charachteristics of how the absorbtion occurs... and each drug and roa has its own specific attributes..
 
But consider this. Snorting MDMA, or taking it sublingually, for example, provides a faster onset of the drug. Has it occurred to you that this fast onset, due to the higher bioavailabilty of these routes of administration, demonstrate a seemingly different effect that could somewhat be described as "speedier"?

Except that sublingual and plugging both come up faster, but are still quite "loved up". The high from snorting MDMA is similar to the "speedy" dopaminergic high that happens when you re-dose MDMA too many times in a night.


Its not just because it "hits you faster", if that was true IV MDMA would be like meth

The reason is not because its closer or farther from the brain, its not because its closer or farther to organs that produce or store neurotransmitters.

Where did anyone say that? What Ive been saying is that MDMA is being broken down for absorption into the bloodstream to the brain, by a system controlled by serotonin, that also is directly linked to the brain.

When you snort, it almost completely bypasses that
 
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Iv mdma has a much faster onset than eating it, and somewhat faster than snorting it... but it still takes 10-15mins... this is because mdma doesnt directly stimulate serotonin receptors... it is similar to an ssri... it changes the way your body manages its endogenous neurotransmitters... so it takes a bit... heroin on the other hand mimics the endogenous chemicals and works almost instantly once it hots the blood stream... hence oral or snorted heroin takes longer than iv... just like mdma...
 
Not the entire stomach, but digestion. Which is why sublingual and rectal are good too


Obviously serotonin isnt breaking down food and such itself, but without serotonin the digestive system cannot work. Ill have some more on that tomorrow but Im going to sleep. Ill start that thread in a couple of days


This is important too though
In recent years the link between the nervous system and the digestive system has been recognized. There is a constant exchange of chemicals and electrical messages between the two systems. In fact, many scientists often refer to them as one entity; the brain-gut axis. Therefore, what affects the stomach will directly affect the brain and vice versa.
http://www.pointofreturn.com/gut_health.html
 
Folley - CI is right on target with his explanation. An example of a drug I have done in 3 different ROA's is cocaine, which doesn't heaviy push the SERT's yet provides a uniquely different high whether smoked, snorted, or eaten. Yes serotonin is used in the gut but that has nothing to do with the SERT in the brain. The MDMA does not bind to the serotonin in the gut, the gut sends it to the liver which dumps some of it into the blood it where it binds to the SERT in the brain and causes a flood of serotonin in your brain. Snorting offers a faster come-up, but not necessarily more bioavailability. Yes the gut has serotonin in it and it also shares 1-2% with the brain and the SERT. But the MDMA does not bind with the serotonin in the gut. It binds to the SERT in your brain
 
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