Can't smoke cannabis after using other drugs - is there any sound correlation?

[Seven-One-Eight]

This question has been puzzling me for a while. I used to think I was the only one who felt this way, but it turns out I'm not. I've talked to a lot of people who can relate to this, and I've seen people discuss it here on BL as well.

After trying psychs, stims, and opiates, I just can't smoke anymore. I get this bummed out feeling that brings along paranoia and irrational fears, something that had never happened when I used to only smoke weed. I used to smoke a couple of times a week, but I quit a few months ago when this problem began to occur. I've now replaced weed with opiates; not exactly the wisest choice, but the feelings just can't compare. Opiates get the job done a million times better these days.

I don't know if this is just some cooincidence or if it actually has some truth behind it. I can't find any studies on it, and I doubt they exist because it's a pretty narrow topic. All I know is this shit sucks. I used to love weed, but now even the slightest thought of it makes me anxious.

 

[Psychedelic Jay]

You are in the same boat as me. I developed an anxiety disorder from weed after doing so many depressants. Weed is strange to me now too. Once I thought I was having a heart attack I was so paranoid. LOL

I can't smoke unless I have a depressant in the mix...

 

[fryingsquirrel]

IDK I've done everything they've bothered to outlaw and quite a few they haven't even heard of yet and I still love the green. But I do know people who have gotten the same affect as you.

 

[Seven-One-Eight]

Yep, we're in the exact same situation. I forgot to mention that smoking with a moderate-high dose of opiates in me is fine, but alone it's unbearable. I hear you with the heart attack feeling, it's definitely happened to me too.

 

[100mgbluepill]

Weed was my first love and it will always be number one in my book. When i took opiates they wouldnt get me as high as i would when i would smoke so i made the combination and i immedietly fell in love. Railing a 40oc and smoking a garcia vega blunt will always be my cup of tea

 

[jebus]

I don't think this is necessarily related to the fact that you have used other drugs. A lot of cannabis users, including ones who never use anything else, will eventually begin to feel the same way you do. I would say that it is possible that using other drugs might speed this process up, if say you were to get used to the 'safety' of an opiate or cocaine or even alcohol high, then the vulnerability that cannabis can produce might seem frightening leading to those symptoms, but I would be hesitant to claim any direct link or correlation between the two.

I think it is just as likely that many cannabis users go on to start using other drugs within a similar sort of time frame after starting cannabis use, the same sort of time frame during which users will begin to notice adverse effects from that use, and so it can be easy to tie the two together when they might not be related at all.

 

[mgrady3]

i've stuck mainly to psychedelics but the green still does it for me

 

[BEEF/N/BROKLY]

I kno OG dustheads in they 30's++ who wont touch weed but ill keep smokin dust... Maybe dey kno mixin make u crazy long term so dey dont, but I dunno its crazy some wont touch it.. I found after smokin dust a lot den stoppin for like a week smokin a blunt makes me go crazy bug out on niggas n shit

 

[Psychedelic Jay]

Cannabinoid receptors can cause a significant hail of anxiety in people with low GABA.

Weed, NMDA antagonist, alcohol, benzos, you name it all cause temporarily lowered GABA levels.

Alcohol and benzos don't cause anxiety because they themselves are agonist of GABA-a receptors.

Weed is a CB-1 and CB-2 receptor agonist, as well as slowing the release of GABA. This is why it can cause super paranoia and anxiety in people who have abused GABA type drugs, or WD from opiate type drugs as well, because they to slow down GABA production.

http://www.ionchannels.org/abstract/pm/9403690
http://en.wikipedia.org/wiki/Cannabinoid_receptor_type_1

 

[k.kat]

This question has been puzzling me for a while. I used to think I was the only one who felt this way, but it turns out I'm not. I've talked to a lot of people who can relate to this, and I've seen people discuss it here on BL as well.

After trying psychs, stims, and opiates, I just can't smoke anymore. I get this bummed out feeling that brings along paranoia and irrational fears, something that had never happened when I used to only smoke weed. I used to smoke a couple of times a week, but I quit a few months ago when this problem began to occur. I've now replaced weed with opiates; not exactly the wisest choice, but the feelings just can't compare. Opiates get the job done a million times better these days.

I don't know if this is just some cooincidence or if it actually has some truth behind it. I can't find any studies on it, and I doubt they exist because it's a pretty narrow topic. All I know is this shit sucks. I used to love weed, but now even the slightest thought of it makes me anxious.

I don't think it has anything to do with stims,
lots of people get this after long term smoking,
just have a big break, (maybe you have got anxiety / depression)
this happened to me few years ago it stated up i couldn't smoke around anyone then eventually i couldn't smoke atoll,
it was horrible as i wanted to smoke, it was weird because the way i felt when i had a smoke was, the best way i can describe it is it was a cross between a bad mushroom trip & a crack comedown horrible (crack was something i only done for a few months and quickly got out of it thank god,)
ended up i had anxiety probs & a previous depression had came back
so took a course of antidepressants & since then i am able to smoke again normally,