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Cannabis and everything... why?

P

Pimp Lazy

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Joined
Jan 5, 2004
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Why does cannabis seem to potentiate everything?

I realize that is a cannabis related question, but I also know that no one in the CD will offer a reasonable response. I know a little bit of cannabinoid pharmacodynamics. Please feel free to go on cannabis related physiology tangents.

Slammin', jammin' and disco-bammingly yours,
~PL~
 
I suspect most psychedelics will do this. Never used heroin on LSD, but I suspect I'd love the hell out of it.

can't anymore, though, but I know I would.
 
Oddly enough I accidentally smoked some black tar thinking it was resin yesterday; I know I know... on both accounts. It's a short story but no one cares to hear it and Yes; Heroin and LSD is wonderful. This question held some special wonder to it yesterday, but I can't for the life of me figure out why at this moment.

Peace,
PL
 
In my experience cannabis creates a tunnel perception effect. The thing you're experiencing and the present moment zooms in and occupies all of your mind and the background fades away (this might also explain the short-term memory problems). Maybe that's what the cannabinoid receptor system regulates.
 
I don't find that cannabis potentiates very much. It mostly clouds/ruins the high of many other drugs.
 
Agreed. Even when I was using, I never smoked cannabis with anything to be honest.

I still think I would have liked heroin and lsd
 
Hammilton said:
I suspect most psychedelics will do this. Never used heroin on LSD, but I suspect I'd love the hell out of it.

can't anymore, though, but I know I would.
Click to expand...

Why can't you? Have you lost the ability to administer heroin to yourself? Don't you mean you shouldn't? And if so, why?

I remember reading that cannabis reduces GABA activity through retrograde signalling? This could account for the potentiation because GABA generally shuts things down as you would know. But this is very wishy washy and just something that I recall reading a while ago, I can't be fucked looking it up again.
 
It was more on the order that when I combine cannabis and any other drug the effects are more than the sum of their parts. I've been looking for why, but I'm not sure there is enough evidence for the in-depth answer I'm looking for. it could just be me and people with similar brains to me; I'm open to that. It used to be if I was on LSD and smoked it was just a waste, but then I seem to have changed and even small amounts of weed send me into orbit.

I thought I couldn't do heroin after my friend died from it, but I proved everybody wrong! You can do heroin too Hammilton! You can doo eet! That being said I did stop using it intentionally after he died in May 2007. I also never IVed it. I don't think anyone should use heroin.

Thanks for the GABA information PS. I can imagine all sorts of reasons why cannabis does what it does, but the specifics are harder to nail down. I guess if I really wanted to know I could put my science degree to use and stop being a musician bum, but that doesn't seem too likely.

So I searched for: cannabis gaba retrograde signaling and voilà! Hurr it be in pärt:

http://www.sciencedirect.com/scienc...serid=10&md5=6f3cd7db6974cbbad8c39f74ccf701a9

Peace,
PL
 
Not everyone can do heroin.

Well, I could do heroin, but it wouldn't do much to me. Being on suboxone medication severely limits the effects one can get from opioid agonists. I tried one time, and the dosage needed to get even a slight effect from heroin was such that my wallet couldn't handle it.
 
I smoke weed with everything. I personally don't feel the high from opiates very much until I smoke. It also seems to induce the nod for me...
 
Yeah I think weed ruins the other highs. Im thinking stoners like their weed with other drugs.

Weed and nitrous il say is an exception. Whoa
 
Hmm, I find pot after opiates sends me into outer space....massive noddery. With a psychedelic, it seems to take over and give me that edgy stoned feeling, so I usually wait til I come down. With stimulants, cannabis usually makes me go kinda crazy....That said, I prefer weed on its own. Feels nice and calming...sometimes at least.
 
pot does play a very unique roll interacting with other drugs. I'm a daily pot smoker and a weekly tripper. A few months ago I quit smoking pot for about 10 days, when I took some LSD. I took 4 or 5 hits of decent acid and for some reason I was unable to trip. Mild body tension, little hints of peripheral visuals but no legit mind warping. I decided that I had to smoke pot to save my trip, so I loaded up a bong and got a N2O balloon ready to exaggerate the rush. Took the biggest bong rip I could followed by several deep breaths of the gas and my mind was catapulted into the center of a vibrating oscillating blindingly bright universe as the pot, N2O and all the LSD kicked in at once. After that the LSD worked full force all night. So for some reason I can't trip without pot.

Another time after i quit pot for a month, I took 4.5 mg of DOC and smoked pot for the first time. It made the DOC trip into one of the most insane and powerful trips of my life, and kept it going full force for over 24 hours!

Another thing that should be considered is that pot is very good at triggering "flashbacks" or exaggerating residual effects of recent psychedelic use. If I smoke good pot I can usually re-create the visuals from my last trip, whatever substance it may be, sometimes even many days later. Or for example my brother had a nightmare trip that traumatized him alot, and whenever he smokes pt even years later now, he gets the same feelings and psychological effects that he had from the trip.

I wonder if pot use preventing dreams has anything to do with this. canabanoids sure are unique!
 
I don't get much of any visuals on moderate dose fungus w/o the herb. I experimented one autumn with a buddy of mine. We obtained about 8g and decided to split it between two weekends, two weeks apart. each time. Both times we both dosed and waited until the body high was in full swing. But for whatever reason, no flowing wood grain or mobile ceiling textures until after we smoked.

The first time, was about 1.5g. We waited 2h 30m after dosage to smoke. Like clockwork, about 30 seconds after the FIRST hit, the visuals popped. The second time, we used about 2.5g (larger dose = more likely to see something). Again, after the body roll was in full swing, and no visuals (slightly less than 3 hours) we went outside under a weeping willow and lit up a bowl. For me, the leaves of the weeping willow instantly turned pink after I let out the first rip. The second rip gave the traditional 'rainbow smoke' I refer to amongst my friends. I tripped for about three more hours (after smoking) each time with fully visual effects.

Conclusion: Must smoke weed with my fungus.
 
ever used heroin on LSD, but I suspect I'd love the hell out of it.
Click to expand...
IME heroin on acid dampens the lsd experience & doesnt enable you to enjoy the full heroin experience since your kinda still liike wwttff is going on? Also, i have to use a lot of chyna white 2 get to where im comfortable for some reason & its not the quality lol. I never tried the combo medium or low doses on that; Go 10+ or go home was my way of thinking.
 
Its the only "drug" that doesn't create objective prejudice, thereby fitting in with everything nicely.

hallucinogens make one too sensitive to combine with anything other than cannabis
 
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