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  • BDD Moderators: Keif’ Richards

Can I mix Rx's?

A

Aporia

Bluelighter
Joined
Aug 8, 2011
Messages
164
So I've built myself a nice tolerance to hydrocodone and oxycodone and my question is can I take 4mg of hydromorphone along with 30mg of either hydrocodone or 30mg of oxycodone and be safe?

I have to take at least 40-50mg of oxycodone to feel anything..

Thank you Bl'ers for your knowledge!
 
No don't do it, YOU WILL DIE, nooo!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
 
Thanks!

I checked the conversion chart and from that it seems like 4mg of hydromorphone would be equivalent to 10mg of oxycodone-I thought that one dilauded would be stronger than one percocet. Did I misunderstand the chart?

Another question for those of you more in the habit...can use this in any other way? The nasal root?
 
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I was fucking with you. But to answer your 2nd question: Yes, yes, and YES! Hydromorphone has a horrible BA when taken orally, giving you less than 20% of the drug. But "the nasal root" gives you 30-40%, so it is much more effective. Seriously, oral hydromorphone is a fucking waste. Granted, it is of just a pumped up hydrocodone if you don't inject it, but the safest(and most effective way if you don't IV) is snorting.

Also, 30mg of hydro is not even close to being the same potency as 30mg oxycodone. You can check the converter; 30mg oxycodone = roughly 60-90mg hydrocodone.

And your right, it often suprises people that DD isn't much stronger than oxy oral, but the only reason hydromorphone is popular is because junkies like me bang it!!!
 
I know you were fucking with me. :p<3 It seemed like a silly question I know. I should have been more forthright with ya'll...

I guess what I was really wondering was would taking 4mg of hydromorphone with the hyrdrocodone (which is what I did...gonna save the other 8mg with the 30mg of oxycodone for a noddin night) get me nice and high orally.

I've never IV'd, although it seems tempting and I've been flirting with the idea since oral pills don't really do it for me anymore (I hate the apap in most of the meds around here and methadone isn't that available) I know myself and don't want the habit that would probably come along with it. ;)

The 4mg and the 30mg didn't really do that much to me. I suppose it's because my tolerance is mid level and the hydromorphone is morphine based and morphine doens't do that much to me orally, at least in the quantities I'm use to. My DOC is methadone because I don't have to redose all day long.

I'm thinking of snorting the rest of the hydromorphone that I have...to be honest I've thought about pluggin it but I haven't walked that road yet AND I haven't done the research on whether or not it's a plugable substance. I just would really like one more nice nod before I'm out of my stash. After that I'm back to only once in a while when it comes my way. Had my wisdom teeth out two weeks ago and went through 120 oxycondones in less than a week. Doens't help that I have an inherited high tolerance to most meds (thanks mom lol)

I love Bl and have been reading from a distance for years-mainly the PD forums, but I've been flirting with opiates for the last four years and have managed to keep it at a rec level.

Anyways, before this becomes a social thread I suppose I should end my long winded reply. Thanks for the info lorne. I appreciate it!


ps..if the link you posted is to the same conversion chart that I looked at on BL it states that 30mg of hydro= 20 mg of oxy...codone that is.

<3<3

Now just got to keep to my wine and not take the rest of my meds till this weekend =D
 
Just checked your link..thanks!

not the same one that I saw, so I'm going to read through it.

Okay! The 8mg is going up the nose this weekend!!!! Awesome, can't wait for the nod :)

Thanks again Lorne667 ;)


....so wait...I can snort the oxycodone? I thought all the apap would contraindicate taking it up the nose?
 
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^ No, DO NOT snort the oxy IF it has APAP in it. You see, you can very well snort oxycodone, but only if it's pure oxy with no tylenol. So things like Oxycontin, Roxi's etc. can be snorted, but anything with tylenol, such as percocet, can be.

And no, it really wasn't a dumb question. I forget not everyone has made it a life's goal to know everything possible about drugs; That said, it makes sense, as much as people go on about how good hydromorphone is, it kind of has a reputation among the general public that it is a badass drug, when in reality, you have to inject it. Also, as for your comment about hydromorphone being morphine based, yes, it technically is, BUT it's actually more similar to hydrocodone than any other drug. You see, when you take hydrocodone, it has(virtually) no effects on it's own. But the liver converts a tiny amount of it in-vivo into hydromorphone, which is then absorbed into the brain. So any effects you get from hydro are actually from hydromorphone, it is just that the body has to convert it. Think of it this way: You take 30mg hydrocodone. 5%, or 3mg, gets converted into H-morphone. This 3mg H-morphone then gets straight into the blood stream. And since the converted dose is absorbed straight form the liver, you get almost 100%, which in this case would be equal to 10-12mg oral H-morphone.
Of course, that is just an off example, point is, opiates and opioids, are, to say the least, unique among other drugs, such as psychadelics ;)

Anyway, I am going off boring ya with details when I could have just gave more links. But I am bored and like to spread the knowledge of the opies...
 
You mean either that 10% gets converted or that only 1.5mg gets converted....right LOL (5% of 30 would be 1.5mg..3mg would be 10%..I'm a math junkie too)

From what I've noticed from hydromorphone, it's a completely different high that hydrocodone. Once upon a time the hydromorphone would have gotten me nodding, but now, many years later only one pill dosen't do jack for me. It's good to know that hydrocodone is converted to hydromorphone though, that means that the two should compliment each other...
A question for you since you're so bored and I do like to absorb as much knowledge as I can about my drugs contrary to your thinking that I probably wouldn't (I'm a knowledge junkie as well LOL) does oxycodone do the same? What is the big difference between the two? I remember being perscribed oxycodone first, then having to switch to hydroconde because the oxy wasn't doing anything for me, then the hydro did wonders, for a minute.


And what about mixing hydromorphone with oxycodone? Would it be a waste of my meds or would they complement each other nicely?

I noticed that taking 30mg of hydroC with 4mg of hydroM didn't do much but make me more of a relaxed stoned feeling, not the normal feeling I would associated with opiates.

Would snorting the 8mg of hydromorphone, then orally taking my 30mg of percs compliment each other or would I be wasting my meds combining the two?

I only ask because you say your bored or else I would be using the search engine and I enjoy the converstation <3

btw...on the combo that I took tonight I have the munchies..which is quite odd. I have never felt hungy with an opiate high?
 
Yes you can combine full agonist opiates. That is fine to do.

This is the kind of information you can learn from using the search engine. Otherwise, posting this in Basic Drug Discussion would have worked better.

I'm closing this thread as it is not OD material, and could have been posted in Basic Drug Discussion (BDD), or searched to find the answer.

EDIT

Upon OP request, I'm sending this over to BDD.
 
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Yes, taking the hydromorphone and percs would definitely enchance one another, but if you plan on snorting the H-morphone(which you should ;) ) then swallow the percs first, then wait 20-30 minutes to rail the H-morphone.

And yes, I meant 1.5 mg! I must have been real high to screw up basic math...

And yeah, oxycodone is also converted by the liver, but it is converted into oxymorphone(vs hydrocodone, which is converted into "hydro"-morphone).
But what separates the 2 is that hydrocodone is completely useless on it's own. Thus, ANY effects you get from hydrocodone are from the small portion that is converted into hydromorphone. This makes it a "pro-drug", because it is simply a vessel for it's metabolite, which is responsible for the effects.

Conversely, oxycodone is actually a potent opioid all by itself. ALso, only a tiny amount of oxycodone converts into oxymorphone. Thus, most of oxycodone's effects are actually from oxycodone itself; granted the conversion to oxymorphone provides additional effects, but it is small enough that even if none of it gets converted you will still get most of the effect from oxycodone. Yet if none of your hydrocodone gets converted, you won't feel a thing. That is why you CAN snort oxycodone, but cannot snort hydrocodone(that, and the fact that hydrocodone is always mixed with APAP)

Note that the conversion of the -codones into the -morphones is mediated by the CYP2D6 enyzme. SO people who are defficient in that enyzme will get little to no effect from hydrocodone, but still get full effects from oxycodone. ALso, oxycodone is MUCH more potent per mg than hydro. Yes, some converters say 1.5x the strength, but that is inaccurate. it is more like 2-3x the strength in most people(and let me stress, most people)
 
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