Butylone and 6-APB cross tolerance

[shishigami]

If I were to do Butylone and then 6-APB two days later would there be a lot of cross tolerance? Would you recommend saving one of them for later?

Also is an issue with combining MXE and an MAOI?

Thanks for the help, I couldn't find the answers when I searched.

 

[QuasiModo]

You probably couldnt find answers because these are all VERY new substances. Personally i wouldnt do any of that stuff you listed but im a huge cynic when it comes to experimental consumption of novel chemicals.

 

[shishigami]

Any more help on this one?

 

[ebola?]

Insofar as both release serotonin, there should be cross-tolerance.

ebola

 

[greenmeanies]

First question has been answered. Second question is very alarming-- I would keep MXE and MAOI drugs VERY VERY far apart. MXE probably acts as a dopamine reuptake inhibitor (stimulant effects) and that would be a very unfun time if your monoamine oxidases are preoccupied?

 

[phatboy303]

As a fan of Butylone, i have to say that its real beauty is in its interactions. Goes very well with MXE. Generally enhances other chemicals rather than overpower them (like Mephedrone). I've mixed Butylone with 5-APB a few times lately and it works best on the second day of an extended session. Brings out the more psychedelic/visual elements.

I would say there is a possible cross tolerance although I find Butylone pretty consistent in potency even after prolonged use (compared to other chems).

 

[Solipsis]

I've got this idea that butylone is relatively very dopaminergic and noradrenergic looking at it's effects. Couldn't be more different from MDAI for example. That would indicate that cross-tolerance could be limited, but general sympathomimetic cross-tolerance (insofar that they are all stims) yes some diminished reaction is to be expected I guess.