wolf of the steppe
Greenlighter
it may have been asked but does buspars dopamine antagonism chump MDPVs DA affinity....if so this could be a pleasant combo............or horrible
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BDD Moderators: Keif’ Richards
Buspar as a mdpv potentiater
- Thread starter wolf of the steppe
- Start date
grrr8Dane
Bluelighter
Buspirone (Buspar) is not going to potentiate MDPV or produce an additive effect. If anything, it is going to lessen the effects of MDPV.
I think that I understand why you're getting this idea, but can you please explicate? Also, the wording of your question is confusing. By "chump" do you mean "trump"?
I think that I understand why you're getting this idea, but can you please explicate? Also, the wording of your question is confusing. By "chump" do you mean "trump"?
wolf of the steppe
Greenlighter
sorry I meant trump...
What about Bu spar or 5HTP in combination with 4-flouroamphetamine or 4-flouromethamphetamine?
What about Bu spar or 5HTP in combination with 4-flouroamphetamine or 4-flouromethamphetamine?
Sadie
Bluelight Crew
Roger&Me
Bluelight Crew
Seeing as buspirone is a dopamine (D2) antagonist, as well as an a1 and a2 adrenergic antagonist, no -- all of the desirable dopaminergic and noradrenergic effects of the MDPV will be greatly lessened or lost completely. In english, buspirone binds to the receptors that dopamine and norepinephrine interact with but without activating the receptors: blocking those "good" chemicals from bonding at the receptor and causing all the good effects.