Bupropion - Experienced - Bupropion, cleaned up and insufflated

[airdusters]

Warning: Do NOT do this unless you have access to anticonvulsant medication. I took 2mg of Xanax and 600mg of Gabapentin before ingesting. High doses of bupropion can cause seizures, especially when insufflated.

Bupropion is a weak NDRI with low oral bioavailability (5% ) that is extensively metabolized by your liver into several metabolites that have almost no affinity for dopamine reuptake inhibition.
So in order to get "high" from it you must use a ROA that bypasses first pass metabolism. Rectal, intranasal, sublingual or intravenous (don't IV this!!!)

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First thing I did was look up the inactive ingredients of my bupropion pill and their solubility in water. Bupropion HCl is extremely soluble in water.


polyethylene glycol - soluble in water
lactose monohydrate - soluble in water
silicon dioxide - soluble in water
hydroxypropyl cellulose - soluble in water


stearic acid - very low solubility in water
Titanium_dioxide - insoluble in water
magnesium stearate - insoluble in water
Microcrystalline cellulose - insoluble in water


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OK, so I can get rid of a decent amount of crap by simply dissolving the pills in water and filtering.

Scraped the coating off ten 150mg Bupropion SR pills with a knife.

Pulverized into a powder. Dissolved powder in a glass cup containing cold water. Not a ton of water, but not so little that its a viscous sludge.

Immediately a large amount of powder sank to the bottom and separated. Poured through a "filter" secured with a rubber band (piece of cloth from a shirt, no coffee filters available) into another cup.

Good amount of gunk remained in the filter. Squeezed liquid out of the filter and into the cup holding the filtered solution. Filtering it a second time proved pointless.

Poured solution into a casserole dish and let evaporate overnight with a small fan blowing gently on it. Left with layer of dry white powder. Some of it crystalline some of it gunky crap.

Scraped, separated crystalline parts as best I could. Insufflated 4 or so small lines. Burns intensely, then numbs. Small rush, vague euphoria, stimulation is noticed. (Note: I have stimulant tolerance)

Heart rate and blood pressure seemed normal. Talkative, more awake. Feels weird. But not bad. Lasted a few hours then bupropion's anticholinergic effects took hold.

Felt like I took 50mg of diphenhydramine. Weak crash from a weak "high".

Worth it? If you're really really bored and have literally nothing else. If you have any sort of stimulant experience or tolerance you will not be impressed with it.

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Summary: Its shit, but better than nothing. Bad for your nose.

Tagged by Xorkoth
substancecode_wellbutrin
substancecode_bupropion
substancecode_antidepressants
substancecode_pharms
explevel_experienced
exptype_neutral
roacode_nasal

 

[Keif' Richards]

I'm not going to lie man. It really irks me that your handle is "Air Dusters". That shit is poisonous and deadly to the Nth degree. I feel like having a handle like that, even if your trying to be comical, is a really bad thing. Some people might look at that and think because this guy does it, maybe it's not so bad. Air Duster and other similar inhalants are not to be grouped together with other drugs of abuse.

Inhalants are in a league entirely of their own. Firstly, Air Duster isn't air at all. It's loaded with highly toxic, compressed gases. They can kill instantly, can literally and I mean literally make you retarded through brain damage and probably possess a whole host of other negative effects that we are unaware of because this shit is too dangerous to even fathom testing its effects on human beings.

I had to get that off my chest.

 

[airdusters]

I'm not going to lie man. It really irks me that your handle is "Air Dusters". That shit is poisonous and deadly to the Nth degree. I feel like having a handle like that, even if your trying to be comical, is a really bad thing. Some people might look at that and think because this guy does it, maybe it's not so bad. Air Duster and other similar inhalants are not to be grouped together with other drugs of abuse.

Inhalants are in a league entirely of their own. Firstly, Air Duster isn't air at all. It's loaded with highly toxic, compressed gases. They can kill instantly, can literally and I mean literally make you retarded through brain damage and probably possess a whole host of other negative effects that we are unaware of because this shit is too dangerous to even fathom testing its effects on human beings.

I had to get that off my chest.

That's fine. I actually got this nick from a World of Warcraft account I bought in like 2008. The login username was 'airdusters'.
If you folks want to change it to something more kosher I'd be cool with it. Doesn't really matter to me what my username is.

 

[opiatekrzy]

Bupropion eww...when I was in prison, that was a popular drug that inmates would snort. I never got into it because it's like idk gives me the chills thinking about it

 

[lazydullard]

I never tried filtering it. I get an effect from 150mg extended release snorted. But it quickly clogs my noses badly and i can't manage to blow it all out.

 

[airdusters]

I never tried filtering it. I get an effect from 150mg extended release snorted. But it quickly clogs my noses badly and i can't manage to blow it all out.

Its hell on your nose even after separating some of the pill fillers. Had bloody mucous for 3 days straight after this little experiment. Personally I'll be sticking with coffee from now on when I'm out of good stims.

 

[MDPV_Psychosis]

I tried using wellbutrin recreationally years ago and I got some limited enjoyment out of doing so. It's important anyone reading this thread understands that abusing wellbutrin can, and often times will, lead to a seizure. It's best to only take it as prescribed.

Snorting the crushed pills gave a small rush and ok high. It was nothing to write home about but I enjoyed it. I wasn't aware of the seizure risk at the time; I used a lot and was lucky nothing bad happened.

I didn't find it to be all that irritating when snorted. It only burned slightly for a short while. Didn't clog up my nose. I guess it can be different for everyone.

It can be prescribed to help with nicotine cravings. For me it was strange, though, while high I chewed a lot more tobacco then I usually do. I felt like I craved nicotine more because the wellbutrin made the tobacco less rewarding/satisfting to use prompting me to chew way more.

I did find a useful use for wellbutrin. I was coming down from a heavy 6 day MDPV binge. I snorted small amounts of wellbutrin every couple of hours. The wellbutrin eased the comedown ALOT. I actually felt somewhat normal, all things considered. I do not know if this was safe to do, but it worked to ease me back down after an especially crazy binge.

 

[kevils92]

So I have a bad habit of doing things to the extreme all the time. I'm prescribed Wellbutrin, (idk what milligram) but whatever it was I took 16 of them, and about an hour in I was dizzy and disoriented, it almost felt like an extremely heavy diphenhydramine trip. Would I do it again? Hell yea but that's just me, I hate being sober so anything is better than nothing

 

[zachamphetamine]

The brand name version of this medication (Wellbutrin XR) does not contain Silicon Dioxide which is the worst of the water-soluble inactives. After I do a CWE on 5-10 150mg pills I scrape the crystaline substance off the plate (looks similar to pure cocaine. Yes, I have used an anhydrous acetone wash to purify 6 grams of coke. I know what 95% pure coke looks like.) Anyway, I load a U-100 syringe with 500-600 mg of pure bupropion and shoot it. I do in fact get a rush. The rush is what you would expect a coke mixed with meth rush to feel like. 30 MINUTES BEFORE I INJECT, I TAKE 3-4 600mg GABAPENTIN TABLETS TO MINIMALIZE THE RISK OF SIZURE!!!!

 

[zachamphetamine]

I'm the same. Be safe and have fun!!

 

[lazydullard]

So I have a bad habit of doing things to the extreme all the time. I'm prescribed Wellbutrin, (idk what milligram) but whatever it was I took 16 of them, and about an hour in I was dizzy and disoriented, it almost felt like an extremely heavy diphenhydramine trip. Would I do it again? Hell yea but that's just me, I hate being sober so anything is better than nothing

I had a pants-pissing seizure on 10 pills oral. But i had been snorting some in the morning too.