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Buprenorphine patch for withdrawals

4thDimension

4thDimension

Greenlighter
Joined
Dec 6, 2010
Messages
38
Location
Sydney
Good afternoon, Good Evening and Goodnight,

I need some advice on these patches and I thank you in advance for any help you can give me.

I am on 20mg Norspan patch for my pain. I had a 14 level spinal fusion 2 years ago and it still hurts. Like many others I developed a taste for my opiate medication and began overusing OC. Using around 80mg I.V per day.

I have quit the OC's now and am using the patch for a dual purpose - pain relief and withdrawal relief. Neither is working very well. I have another 20 patch and am wondering if I could put that on so I would be transdermal 40mg buprenorphine.

Using two of these patches, would it be more similar to doses used with subutex? I am somewhat hesitant to stick on the other patch as these things can cause quite severe side effects.
 
*bump*

Hi 4thDimension,

Unusual that nobody has replied to this yet. It's not an area I know anything about I'm sorry, but if you don't get any replies you could try PMing a mod like Leftwing, he's right up on this stuff.
 
i've got an article or two about the transdermal bupe patches being trialled and used for ORT; i think a european country and america have trialled them. i'll drag some info up a bit later today.

fwiw i was on 2 x 20mg patches for pain management for a decent period of time and they worked fantastic. you needn't worry about not being able to use other full agonists for breakthrough pain as the blockade effect comes in at around the 2mg mark. i would use oxycontin, (IM) morphine and codeine on top of the patches for breakthrough pain.

shoot me a pm if you like:)
 
Thanks for the info. I took the extra 20mg patch off as it made me feek as though my head was pulsating and I had extreme vasodilation. I just took some physeptone for withdrawals and it is working brilliantly :)
 
yeah i had an allergic reaction to the silicon matrix adhesive and was suffering migraines as a side effect from the transdermal patches. however, i've never had any problems with headaches when i've used subutex (pure bupe, no naloxone).

i haven't had much of a chance to drag up those studies but will go through my external harddrive either tonight or tomorrow after i finish up at my 2nd day of my new job trial and send them though if you're interested. just let me know:)

good luck with your treatment! once again i'm looking to get onto the buprenorphone program now that i'm situated in a city where there's plenty of PM Dr's as well as ORT Clinics. that or i'll probably end back up on either morphine or oxycontin.
 
The patches deliver those 20 mg over a period of 72 hours so even if you are one of the small number of opiate/opioid addicts who can even gain benefit from buprenorphine at any dosage, the transdermal system is utterly worthless.
 
rachamim was more attacking the transdermal patches.

rachamim - have you've any personal experiencing using them for PM? i have and despite the allergic reaction to the matrix adhesive i had and some problems with the patch staying stuck to my biceps/chest they were brilliant, albeit i did suffer one of the more common headache side effects on it. at those doses you're able to use other meds such as codeine, oxy, morph, etc without the consequences of precipitated withdrawal.
 
Leftwing: When you take Buperex, the form of Buprenorphine given in Opioid Substitution Therapy (MAT) it is released over the course of 24 to 36 hours. When you take the patch it is released over the course of 72 hours. Your serum levels are never going to be at a therapeutic level unless you are perhaps sated on 2 mgs.of Bupe.

No, I gain no benefit from any form of Buprenorphine. It has a metabolic ceiling of 16 mgs. (though some swear they gain effect at up to 24 mgs, recent work in the US dispels it). I have multiple enzymes (like many Middle Easterners) and so it takes a lot to sate me. When I use methadone I dose from 220 to 260 depending upon whether I feel up to going through the whole Trough Test.

Most long term addicts aren't going benefit from it either for the same reason as well as other possible reasons that are being investigated (receptor interaction, etc.,etc).
 
Leftwing: When you take Buperex, the form of Buprenorphine given in Opioid Substitution Therapy (MAT) it is released over the course of 24 to 36 hours. When you take the patch it is released over the course of 72 hours. Your serum levels are never going to be at a therapeutic level unless you are perhaps sated on 2 mgs.of Bupe.
Click to expand...

i'm aware of that.

i have chronic pain and at the max dosage of 2 x 20mg patches it satiated all my needs. i have spondylolisthes l4 through to s1 with nerve damage stemming from that and sclerosis on facet joints, curvature in lower spine too.

buprenorphine is one drug that works extremely well for me for PM. i disagree about you "uttery worthless" comment about the transdermal system through anecdotal, research as well as me own experience, though agree i would prefer subutex in the long run.
 
On Chronic Pain? I think anything that glues onto your receptors is a big problem but how much more so a substance that has fair Antagonism? What will you do for breakthrough pain? If it works for you that is the bottom line but I don't see it becoming popular...then again who would have thought methadone would become a pain med? At least that clusterfuc* has reversed itself.
 
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